Hub : Traits : dissection: PC 2 of all traits : ← →

chr9:65,337,960-67,403,242

Best TWAS P=1.107444e-08 · Best GWAS P=3.515671e-08 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	BLA	Plekhm3	gene expression	ENSRNOG00000023760	0.05	0.00	blup	1335	0.01	4.9e-02	-4.7	-5.3	1.1e-07	0.98	0.48	0.42	FALSE
2	Brain	Cryga	alternative TSS	ENSRNOT00000019963	0.04	0.04	lasso	27	0.05	1.2e-05	-5.3	-5.2	1.9e-07	0.97	0.55	0.45	FALSE
3	Brain	Cryga	alternative TSS	ENSRNOT00000072983	0.04	0.04	lasso	25	0.05	1.5e-05	-5.3	5.2	1.9e-07	-0.97	0.54	0.45	FALSE
4	Brain	Mettl21a	gene expression	ENSRNOG00000014212	0.05	0.04	enet	329	0.04	2.0e-04	-5.3	-5.4	7.8e-08	0.95	0.48	0.49	TRUE
5	Brain	Idh1	gene expression	ENSRNOG00000015020	0.02	0.02	top1	1	0.02	4.1e-03	-5.4	-5.4	5.4e-08	0.98	0.06	0.04	FALSE
6	Brain	Pikfyve	gene expression	ENSRNOG00000015158	0.05	0.06	enet	61	0.06	2.3e-06	-5.3	5.3	1.3e-07	-0.95	0.53	0.47	FALSE
7	Brain	Plekhm3	gene expression	ENSRNOG00000023760	0.04	0.05	enet	12	0.06	5.3e-06	-5.2	-5.2	2.2e-07	-0.08	0.52	0.48	TRUE
8	IL	Fzd5	gene expression	ENSRNOG00000014678	0.17	0.07	top1	1	0.07	1.0e-02	-5.3	5.3	1.4e-07	-0.97	0.07	0.05	FALSE
9	Liver	Idh1	isoform ratio	ENSRNOT00000020322	0.03	0.00	blup	1626	0.00	9.8e-02	-4.6	5.6	2.2e-08	-0.95	0.40	0.36	FALSE
10	Liver	Idh1	isoform ratio	ENSRNOT00000108404	0.03	0.00	blup	1626	0.01	6.4e-02	-4.6	-5.6	2.0e-08	0.95	0.42	0.39	FALSE
11	NAcc	Pth2r	gene expression	ENSRNOG00000015259	0.14	0.03	blup	2045	0.05	2.6e-02	-4.7	5.6	1.9e-08	-0.84	0.35	0.21	FALSE
12	NAcc2	Pth2r	gene expression	ENSRNOG00000015259	0.11	0.07	blup	2050	0.10	7.6e-06	-4.7	5.7	1.1e-08	-0.87	0.81	0.17	TRUE
13	PL2	Fzd5	gene expression	ENSRNOG00000014678	0.06	0.03	top1	1	0.03	1.2e-02	-5.5	5.5	4.9e-08	-0.97	0.05	0.04	FALSE
14	PL2	Cryga	intron excision ratio	chr9:66486750:66490303	0.10	0.10	top1	1	0.10	3.8e-06	-5.2	5.2	2.5e-07	-0.99	0.26	0.11	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.