Hub : Traits : Pavlov. Cond. index score : →

chr1:151,194,048-154,174,144

Trait: Pavlov. Cond. index score

Best TWAS P=2.315924e-07 · Best GWAS P=9.701427e-07 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Thap12	mRNA stability	ENSRNOG00000053923	0.09	0.03	blup	1517	0.05	2.1e-06	-4.8	-5.2	2.4e-07	0.88	0.38	0.62	FALSE
2	BLA	Capn5	mRNA stability	ENSRNOG00000014251	0.10	0.02	blup	1520	0.07	1.8e-04	-4.2	5.1	3.1e-07	-0.83	0.36	0.59	FALSE
3	Brain	Dgat2	gene expression	ENSRNOG00000016573	0.28	0.26	lasso	8	0.28	8.2e-26	-4.7	-5.1	3.1e-07	0.93	0.36	0.64	FALSE
4	Brain	Capn5	mRNA stability	ENSRNOG00000014251	0.17	0.16	lasso	31	0.18	2.1e-16	-4.8	5.1	3.0e-07	-0.90	0.20	0.80	FALSE
5	LHb	Rsf1	gene expression	ENSRNOG00000024194	0.58	0.04	lasso	5	0.08	5.9e-03	3.9	5.1	3.4e-07	-0.68	0.21	0.26	FALSE
6	NAcc	Thap12	mRNA stability	ENSRNOG00000053923	0.12	0.07	blup	1517	0.09	4.6e-07	-4.5	-5.2	2.3e-07	0.94	0.28	0.72	TRUE
7	PL	Emsy	gene expression	ENSRNOG00000015560	0.05	0.01	blup	1469	0.02	1.1e-02	-4.6	-5.2	2.3e-07	0.89	0.38	0.42	FALSE
8	PL	Thap12	gene expression	ENSRNOG00000053923	0.11	0.05	lasso	14	0.08	1.0e-06	4.2	5.1	2.8e-07	-0.84	0.53	0.47	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.