chr10:89,400,319-95,911,835

Trait: Bone: minimum diameter

Best TWAS P=2.80e-09 · Best GWAS P=2.31e-08 conditioned to NaN

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose Cep112 alternative polyA XM_039085647.1 0.03 2155 0.02 1.6e-03 5.19 2.11e-07 0.39 FALSE
Adipose Cep112 alternative polyA XM_039085653.1 0.07 2155 0.07 2.3e-08 -5.36 8.39e-08 0.43 FALSE
Adipose Ddx5 alternative polyA XM_008768313.3 0.06 1 0.02 1.1e-03 5.32 1.03e-07 0.24 FALSE
Adipose Arsg alternative TSS NM_001047877.2 0.08 40 0.05 3.1e-06 -5.45 5.04e-08 0.46 FALSE
Adipose Arsg alternative TSS XM_006247601.4 0.07 9 0.06 2.3e-07 -5.56 2.76e-08 0.55 FALSE
Adipose Arsg alternative TSS XM_008768369.2 0.04 2838 0.01 2.3e-02 -5.5 3.80e-08 0.52 FALSE
Adipose Arsg alternative TSS XM_006247601.4 0.06 9 0.05 4.3e-06 -5.44 5.24e-08 0.55 FALSE
Adipose Arsg alternative TSS XM_008768369.2 0.04 2838 0.02 2.6e-03 -5.56 2.68e-08 0.49 FALSE
Adipose LOC102550334 alternative TSS XR_005490503.1 0.08 2163 0.01 1.0e-02 5.23 1.67e-07 0.2 FALSE
Adipose Arsg gene expression Arsg 0.36 2838 0.24 8.1e-27 5.34 9.18e-08 0.55 TRUE
Adipose C10h17orf58 gene expression C10h17orf58 0.33 51 0.42 7.2e-51 -5.52 3.41e-08 0.68 FALSE
Adipose Kcnh6 gene expression Kcnh6 0.04 34 0.02 3.8e-03 5.18 2.25e-07 0.1 TRUE
Adipose LOC120095195 gene expression LOC120095195 0.02 1 0.02 1.6e-03 -5.35 8.66e-08 0.07 FALSE
Adipose Polg2 gene expression Polg2 0.03 1 0.01 1.0e-02 5.37 7.84e-08 0.05 FALSE
Adipose Smurf2 gene expression Smurf2 0.25 1 0.24 8.8e-27 5.28 1.30e-07 0.76 FALSE
Adipose Taco1 gene expression Taco1 0.05 1 0.04 2.3e-05 5.47 4.49e-08 0.47 FALSE
Adipose Tanc2 gene expression Tanc2 0.19 1 0.19 4.3e-21 -5.46 4.69e-08 0.83 FALSE
Adipose Arsg isoform ratio XR_005489859.1 0.06 2838 0.03 1.6e-04 -5.42 6.11e-08 0.54 FALSE
Adipose Cep112 isoform ratio XM_039085653.1 0.06 2155 0.05 2.3e-06 -5.34 9.08e-08 0.4 FALSE
Adipose Cep112 isoform ratio XR_005489759.1 0.04 2155 0.02 1.2e-03 -5.32 1.03e-07 0.38 FALSE
Adipose Ddx5 isoform ratio NM_001007613.1 0.06 17 0.03 2.4e-04 5.23 1.71e-07 0.38 FALSE
Adipose Helz isoform ratio XM_006247565.4 0.02 1771 0.01 3.6e-02 -5.31 1.11e-07 0.38 FALSE
Adipose Icam2 intron excision ratio chr10_91313564_91313641 0.05 1 0.05 7.0e-06 -5.4 6.78e-08 0.62 FALSE
Adipose Icam2 intron excision ratio chr10_91313731_91315221 0.07 1 0.08 2.6e-09 5.48 4.35e-08 0.78 FALSE
Adipose Pecam1 intron excision ratio chr10_91591524_91614529 0.06 1 0.05 3.1e-06 -5.57 2.53e-08 0.89 FALSE
Adipose Ddx5 mRNA stability Ddx5 0.06 12 0.08 1.4e-09 -5.48 4.15e-08 0.44 FALSE
Adipose Psmd12 mRNA stability Psmd12 0.05 1 0.05 1.9e-06 -5.37 7.71e-08 0.73 FALSE
Adipose Scn4a mRNA stability Scn4a 0.04 1 0.03 5.1e-04 5.41 6.24e-08 0.62 FALSE
BLA Helz alternative polyA XM_039085638.1 0.09 2037 0.03 6.7e-03 -5.27 1.36e-07 0.34 TRUE
BLA Fam20a alternative TSS XM_039086179.1 0.22 2993 0.16 6.0e-09 5.54 2.99e-08 0.63 FALSE
BLA Pecam1 alternative TSS XM_039085778.1 0.19 154 0.22 4.1e-12 -5.42 5.85e-08 0.5 FALSE
BLA Ace gene expression Ace 0.16 37 0.18 1.0e-09 -5.57 2.55e-08 0.42 FALSE
BLA C10h17orf58 gene expression C10h17orf58 0.52 406 0.42 1.9e-24 5.36 8.45e-08 0.74 FALSE
BLA Dcaf7 gene expression Dcaf7 0.06 12 0.05 1.7e-03 5.51 3.57e-08 0.21 FALSE
BLA Fam20a gene expression Fam20a 0.25 2993 0.14 3.8e-08 -5.49 4.10e-08 0.64 FALSE
BLA LOC120095203 gene expression LOC120095203 0.27 2596 0.27 6.7e-15 5.41 6.20e-08 0.53 FALSE
BLA Strada gene expression Strada 0.31 53 0.37 5.3e-21 -5.32 1.04e-07 0.38 FALSE
BLA Wipi1 gene expression Wipi1 0.61 39 0.48 9.7e-29 5.41 6.43e-08 0.62 FALSE
BLA Helz isoform ratio XM_006247562.4 0.07 2037 0.03 1.6e-02 -5.18 2.19e-07 0.32 FALSE
BLA Fam20a intron excision ratio chr10_94656158_94696599 0.11 2993 0.11 2.8e-06 -5.26 1.45e-07 0.09 FALSE
BLA Marchf10 intron excision ratio chr10_90333190_90335149 0.15 86 0.07 1.3e-04 5.24 1.64e-07 0.32 FALSE
BLA Bptf mRNA stability Bptf 0.04 1851 0.01 5.4e-02 5.37 7.79e-08 0.54 TRUE
BLA Strada mRNA stability Strada 0.08 1 0.1 9.2e-06 -5.43 5.77e-08 0.51 FALSE
Brain Ddx5 alternative polyA NM_001007613.1 0.06 1 0.05 9.2e-06 -5.29 1.21e-07 0.67 FALSE
Brain Ddx5 alternative polyA XM_008768313.3 0.06 1 0.06 1.5e-06 5.29 1.21e-07 0.68 FALSE
Brain Psmd12 alternative polyA NM_001005875.1 0.15 28 0.19 4.5e-17 5.38 7.55e-08 0.51 FALSE
Brain Psmd12 alternative polyA XM_039085636.1 0.15 30 0.18 9.7e-17 -5.39 7.08e-08 0.5 FALSE
Brain C10h17orf58 gene expression C10h17orf58 0.42 25 0.52 1.4e-56 -5.31 1.13e-07 0.74 FALSE
Brain LOC120095203 gene expression LOC120095203 0.31 2596 0.31 3.7e-29 5.25 1.50e-07 0.54 FALSE
Brain Scn4a gene expression Scn4a 0.42 15 0.4 1.3e-39 5.38 7.39e-08 0.73 FALSE
Brain Wipi1 gene expression Wipi1 0.74 2923 0.61 2.4e-71 5.65 1.63e-08 0.61 FALSE
Brain C10h17orf58 isoform ratio XM_039086648.1 0.04 2008 0.01 5.4e-02 5.28 1.31e-07 0.53 FALSE
Brain Ddx5 isoform ratio NM_001007613.1 0.08 14 0.07 8.7e-07 5.5 3.70e-08 0.72 FALSE
Brain Ddx5 isoform ratio XM_039085631.1 0.06 2198 0.04 1.0e-04 -5.37 8.08e-08 0.72 FALSE
Brain Prkar1a isoform ratio XM_008768311.2 0.03 2945 0.01 6.3e-02 5.24 1.57e-07 0.37 FALSE
Brain Psmd12 isoform ratio NM_001005875.1 0.09 1 0.11 4.1e-10 -5.38 7.55e-08 0.75 FALSE
Brain Psmd12 isoform ratio XM_039085636.1 0.09 1 0.1 7.0e-10 5.38 7.55e-08 0.75 FALSE
Brain Tex2 isoform ratio NM_001100554.1 0.05 8 0.05 4.3e-05 5.56 2.69e-08 0.35 FALSE
Brain Tex2 isoform ratio XM_006247647.3 0.05 2268 0.05 2.9e-05 5.41 6.23e-08 0.46 FALSE
Brain LOC120095188 intron excision ratio chr10_90474854_90527932 0.04 2540 0.04 2.8e-04 5.45 5.00e-08 0.4 FALSE
Brain Bptf mRNA stability Bptf 0.12 1 0.13 3.6e-12 -5.26 1.42e-07 0.73 FALSE
Brain Taco1 mRNA stability Taco1 0.14 37 0.18 1.0e-16 -5.46 4.74e-08 0.69 FALSE
Eye Pitpnc1 isoform ratio XM_039087431.1 0.38 210 0.18 1.1e-03 5.44 5.39e-08 0.37 FALSE
IL Milr1 alternative polyA XM_039086726.1 0.23 1 0.04 4.4e-02 5.46 4.73e-08 0.06 FALSE
IL Psmd12 alternative polyA XM_039085636.1 0.14 8 0.07 7.8e-03 -5.31 1.08e-07 0.33 TRUE
IL Cyb561 alternative TSS XM_039086163.1 0.29 17 0.06 1.3e-02 -5.52 3.40e-08 0.34 FALSE
IL C10h17orf58 gene expression C10h17orf58 0.34 2008 0.25 1.3e-06 -5.53 3.27e-08 0.61 FALSE
IL Helz gene expression Helz 0.21 104 0.15 1.7e-04 5.41 6.15e-08 0.4 FALSE
IL Smurf2 gene expression Smurf2 0.53 32 0.36 1.9e-09 5.44 5.33e-08 0.55 FALSE
IL Strada gene expression Strada 0.35 26 0.11 1.4e-03 5.37 8.06e-08 0.42 FALSE
IL Wipi1 gene expression Wipi1 0.37 2923 0.1 2.7e-03 5.41 6.30e-08 0.42 FALSE
IL Axin2 isoform ratio XM_039085704.1 0.18 2034 0.1 2.0e-03 -5.21 1.91e-07 0.26 FALSE
IL Pecam1 mRNA stability Pecam1 0.23 26 0.13 4.1e-04 -5.38 7.28e-08 0.41 FALSE
IL Strada mRNA stability Strada 0.34 1 0.3 5.8e-08 -5.45 5.10e-08 0.42 FALSE
LHb Cyb561 alternative TSS NM_001107056.3 0.39 2144 0.16 1.1e-04 -5.79 6.84e-09 0.27 FALSE
LHb Cyb561 alternative TSS XM_039086165.1 0.36 2144 0.16 1.3e-04 5.8 6.52e-09 0.27 FALSE
LHb Bptf gene expression Bptf 0.35 1 0.1 2.5e-03 5.52 3.36e-08 0.08 FALSE
LHb Scn4a gene expression Scn4a 0.58 4 0.24 2.2e-06 5.51 3.59e-08 0.7 FALSE
LHb Wipi1 gene expression Wipi1 0.61 2923 0.29 1.6e-07 5.36 8.27e-08 0.6 FALSE
LHb Marchf10 isoform ratio XR_005489857.1 0.29 124 0.13 4.9e-04 5.74 9.61e-09 0.32 FALSE
LHb Taco1 mRNA stability Taco1 0.17 1 0.15 1.9e-04 5.35 8.67e-08 0.07 FALSE
Liver LOC120095200 alternative polyA XR_005490497.1 0.2 2144 0.17 9.9e-19 5.51 3.51e-08 0.55 FALSE
Liver LOC120095200 alternative polyA XR_005490496.1 0.21 164 0.22 7.6e-24 -5.49 3.96e-08 0.55 FALSE
Liver Rgs9 alternative polyA NM_019224.2 0.06 4 0.04 2.2e-05 -5.94 2.80e-09 0.35 TRUE
Liver Rgs9 alternative polyA XM_039085765.1 0.06 2496 0.04 5.1e-05 5.74 9.28e-09 0.42 FALSE
Liver Abca6 alternative TSS XM_039087447.1 0.3 17 0.24 6.7e-26 -5.27 1.38e-07 0.45 FALSE
Liver Abca9 alternative TSS XM_039087440.1 0.03 3128 0.01 9.4e-03 -5.49 4.04e-08 0.19 FALSE
Liver Icam2 alternative TSS NM_001007725.1 0.34 17 0.29 8.7e-33 -5.48 4.14e-08 0.7 FALSE
Liver Icam2 alternative TSS XM_039086420.1 0.07 10 0.03 2.5e-04 5.22 1.80e-07 0.68 FALSE
Liver Ace gene expression Ace 0.08 2130 0.07 2.7e-08 -5.61 2.01e-08 0.61 FALSE
Liver LOC120095301 gene expression LOC120095301 0.04 2056 0.02 2.1e-03 -5.24 1.63e-07 0.59 FALSE
Liver Icam2 isoform ratio NM_001007725.1 0.19 1 0.14 1.5e-15 5.4 6.78e-08 0.7 FALSE
Liver Icam2 isoform ratio XM_006247627.4 0.05 1 0.04 3.7e-05 -5.45 5.10e-08 0.46 FALSE
Liver Icam2 isoform ratio XM_008768379.3 0.04 2147 0.02 3.6e-03 5.33 9.96e-08 0.66 FALSE
Liver Nol11 isoform ratio XR_005490485.1 0.04 1 0.03 4.4e-04 -5.27 1.40e-07 0.31 FALSE
Liver Wipi1 isoform ratio XM_039086173.1 0.08 2918 0.06 6.0e-07 5.45 4.94e-08 0.55 FALSE
Liver Icam2 intron excision ratio chr10_91313731_91315221 0.3 26 0.27 4.2e-30 -5.5 3.77e-08 0.7 TRUE
Liver Wipi1 intron excision ratio chr10_94553836_94564588 0.06 2918 0.03 7.5e-04 -5.62 1.95e-08 0.45 FALSE
Liver Map3k3 mRNA stability Map3k3 0.03 1 0.02 2.8e-03 5.45 5.10e-08 0.06 FALSE
Liver Psmd12 mRNA stability Psmd12 0.02 1800 0.03 3.3e-04 5.3 1.14e-07 0.47 FALSE
Liver Taco1 mRNA stability Taco1 0.09 1897 0.11 6.0e-12 -5.68 1.31e-08 0.69 FALSE
NAcc Ddx5 alternative polyA NM_001007613.1 0.04 1 0.03 2.9e-04 -5.45 5.00e-08 0.55 FALSE
NAcc Ddx5 alternative polyA XM_008768313.3 0.03 1 0.02 1.2e-03 5.53 3.28e-08 0.38 FALSE
NAcc Psmd12 alternative polyA XM_039085636.1 0.07 1 0.1 1.9e-11 5.23 1.72e-07 0.58 FALSE
NAcc Ace gene expression Ace 0.09 1 0.08 1.1e-09 5.4 6.58e-08 0.68 FALSE
NAcc C10h17orf58 gene expression C10h17orf58 0.52 186 0.57 5.5e-80 5.45 5.05e-08 0.76 FALSE
NAcc Cacng4 gene expression Cacng4 0.14 1 0.15 4.5e-17 -5.21 1.93e-07 0.56 FALSE
NAcc Ccdc47 gene expression Ccdc47 0.04 2067 0.04 3.2e-05 5.65 1.57e-08 0.69 FALSE
NAcc Ddx42 gene expression Ddx42 0.02 1 0.02 3.3e-03 5.46 4.70e-08 0.09 FALSE
NAcc LOC108352143 gene expression LOC108352143 0.05 3 0.06 6.0e-07 -5.63 1.83e-08 0.65 FALSE
NAcc Mrc2 gene expression Mrc2 0.25 85 0.09 1.4e-10 -5.22 1.81e-07 0.24 FALSE
NAcc Prkar1a gene expression Prkar1a 0.03 21 0.02 8.4e-04 -5.37 7.92e-08 0.6 FALSE
NAcc Psmd12 gene expression Psmd12 0.02 2001 0.02 2.3e-03 -5.24 1.57e-07 0.52 FALSE
NAcc Scn4a gene expression Scn4a 0.42 15 0.43 1.4e-54 5.47 4.48e-08 0.74 FALSE
NAcc Strada gene expression Strada 0.15 29 0.23 1.7e-26 -5.23 1.66e-07 0.15 FALSE
NAcc Tanc2 gene expression Tanc2 0.23 1 0.12 1.5e-13 5.28 1.29e-07 0.65 FALSE
NAcc Wipi1 gene expression Wipi1 0.64 48 0.54 5.1e-74 5.53 3.18e-08 0.62 FALSE
NAcc Ddx5 isoform ratio NM_001007613.1 0.02 2198 0.01 4.0e-02 5.48 4.31e-08 0.62 FALSE
NAcc Fam20a isoform ratio XM_039086179.1 0.07 2993 0.06 5.7e-08 5.34 9.42e-08 0.19 FALSE
NAcc Psmd12 isoform ratio NM_001005875.1 0.05 12 0.08 3.7e-09 5.46 4.66e-08 0.49 FALSE
NAcc Dcaf7 mRNA stability Dcaf7 0.07 1 0.06 1.4e-07 -5.42 5.94e-08 0.7 FALSE
NAcc Limd2 mRNA stability Limd2 0.02 1 0.01 1.4e-02 5.38 7.62e-08 0.05 FALSE
NAcc Strada mRNA stability Strada 0.08 76 0.13 2.4e-14 -5.18 2.22e-07 0.12 FALSE
NAcc Taco1 mRNA stability Taco1 0.2 25 0.12 2.4e-13 5.25 1.50e-07 0.68 TRUE
OFC Ace gene expression Ace 0.45 34 0.27 4.7e-07 -5.61 2.08e-08 0.64 FALSE
OFC Mettl2 gene expression Mettl2 0.75 265 0.36 1.5e-09 -5.25 1.52e-07 0.17 FALSE
OFC Marchf10 isoform ratio XR_005489857.1 0.36 308 0.14 3.4e-04 5.25 1.54e-07 0.22 FALSE
OFC Strada isoform ratio NM_001415111.1 0.18 12 0.08 5.2e-03 5.45 5.08e-08 0.56 FALSE
PL Fam20a alternative polyA NM_001012237.2 0.05 2993 0.03 1.4e-04 -5.29 1.22e-07 0.17 FALSE
PL Fam20a alternative polyA XM_039086178.1 0.05 2993 0.04 3.8e-05 5.29 1.21e-07 0.18 FALSE
PL Psmd12 alternative polyA NM_001005875.1 0.11 2001 0.17 6.4e-18 5.37 7.88e-08 0.5 FALSE
PL Psmd12 alternative polyA XM_039085636.1 0.11 2001 0.17 3.5e-18 -5.37 7.74e-08 0.52 FALSE
PL Fam20a alternative TSS XM_039086179.1 0.11 2993 0.14 1.2e-15 5.31 1.11e-07 0.64 FALSE
PL Marchf10 alternative TSS XM_017597337.2 0.03 2477 0.02 1.9e-03 5.6 2.12e-08 0.52 FALSE
PL Ace gene expression Ace 0.18 24 0.28 9.8e-31 -5.49 4.09e-08 0.69 FALSE
PL C10h17orf58 gene expression C10h17orf58 0.43 97 0.51 1.1e-64 5.52 3.43e-08 0.76 FALSE
PL Ccdc47 gene expression Ccdc47 0.08 6 0.05 1.2e-06 5.33 9.94e-08 0.46 FALSE
PL Ern1 gene expression Ern1 0.04 2323 0.04 1.0e-05 5.34 9.43e-08 0.34 FALSE
PL Fam20a gene expression Fam20a 0.32 2993 0.27 1.4e-29 -5.42 6.09e-08 0.65 TRUE
PL Icam2 gene expression Icam2 0.04 2153 0.03 1.1e-04 5.19 2.05e-07 0.38 FALSE
PL Mrc2 gene expression Mrc2 0.11 16 0.12 2.9e-13 5.32 1.03e-07 0.37 FALSE
PL Strada gene expression Strada 0.21 13 0.32 1.7e-36 5.18 2.18e-07 0.16 FALSE
PL Wipi1 gene expression Wipi1 0.47 2923 0.42 1.4e-50 5.58 2.38e-08 0.62 FALSE
PL C10h17orf58 isoform ratio XM_039086648.1 0.03 24 0.03 5.8e-04 -5.22 1.83e-07 0.66 FALSE
PL Psmd12 isoform ratio NM_001005875.1 0.08 8 0.1 1.6e-11 5.26 1.48e-07 0.51 FALSE
PL Psmd12 isoform ratio XM_039085636.1 0.09 10 0.11 1.3e-11 -5.33 9.87e-08 0.55 FALSE
PL Cyb561 intron excision ratio chr10_90884535_90888604 0.09 12 0.1 2.2e-11 -5.69 1.25e-08 0.07 FALSE
PL Map3k3 intron excision ratio chr10_91078047_91080296 0.03 1 0 9.5e-02 5.47 4.41e-08 0.06 FALSE
PL Bptf mRNA stability Bptf 0.07 17 0.09 4.3e-10 5.4 6.62e-08 0.74 FALSE
PL Cep95 mRNA stability Cep95 0.03 1 0.04 4.0e-05 -5.54 3.01e-08 0.8 FALSE
PL Dcaf7 mRNA stability Dcaf7 0.1 1 0.08 2.1e-09 -5.48 4.37e-08 0.76 FALSE
PL Pecam1 mRNA stability Pecam1 0.12 42 0.17 3.6e-18 -5.31 1.11e-07 0.54 FALSE
PL Taco1 mRNA stability Taco1 0.09 11 0.1 1.4e-10 -5.24 1.57e-07 0.68 FALSE
pVTA Cyb561 alternative TSS XM_008768357.3 0.23 7 0.06 1.9e-03 5.41 6.27e-08 0.12 FALSE
pVTA LOC108352148 gene expression LOC108352148 0.08 11 0.03 2.1e-02 5.37 7.69e-08 0.3 FALSE
pVTA LOC120095203 gene expression LOC120095203 0.2 2596 0.12 6.6e-06 5.42 5.85e-08 0.53 FALSE
pVTA Tex2 gene expression Tex2 0.24 2237 0.24 1.1e-10 5.42 6.09e-08 0.41 FALSE
pVTA Cyb561 intron excision ratio chr10_90884535_90888604 0.21 2113 0.08 2.1e-04 5.29 1.20e-07 0.08 FALSE
pVTA Marchf10 intron excision ratio chr10_90333190_90336385 0.1 28 0.02 3.8e-02 -5.23 1.72e-07 0.14 FALSE
pVTA Taco1 mRNA stability Taco1 0.07 1 0.1 5.7e-05 5.47 4.63e-08 0.19 FALSE
RMTg Strada intron excision ratio chr10_91117571_91123739 0.09 1969 0.05 1.7e-02 5.58 2.45e-08 0.41 FALSE
RMTg Mettl2 mRNA stability Mettl2 0.17 4 0.11 7.3e-04 -5.32 1.04e-07 0.19 FALSE