Best TWAS P=1.756313e-07 · Best GWAS P=5.587292e-08 conditioned to 8.685797e-126
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | IL | Cyp26a1 | gene expression | ENSRNOG00000016750 | 0.31 | 0.18 | blup | 2500 | 0.21 | 9.5e-06 | 4.9 | 5.1 | 3.0e-07 | 0.94 | 0.38 | 0.61 | FALSE |
| 2 | Liver | Exoc6 | gene expression | ENSRNOG00000036601 | 0.06 | 0.05 | top1 | 1 | 0.05 | 2.6e-06 | 5.2 | -5.2 | 1.8e-07 | -0.90 | 0.08 | 0.91 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.