Best TWAS P=9.64e-14 · Best GWAS P=5.37e-16 conditioned to 6.24e-265
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLA | LOC102547233 | gene expression | LOC102547233 | 0.6 | 16 | 0.37 | 5.8e-21 | -6.76 | 1.39e-11 | 0.03 | FALSE |
| BLA | LOC102549521 | gene expression | LOC102549521 | 0.11 | 1 | 0.03 | 6.0e-03 | -5.46 | 4.72e-08 | 0.04 | FALSE |
| Brain | LOC102549596 | alternative polyA | XR_005490525.1 | 0.22 | 1 | 0.12 | 4.2e-11 | -5.83 | 5.52e-09 | 0.05 | FALSE |
| Brain | LOC102549596 | alternative polyA | XR_005490526.1 | 0.22 | 1 | 0.12 | 3.3e-11 | 5.83 | 5.52e-09 | 0.05 | FALSE |
| Brain | LOC102547233 | alternative TSS | XR_594922.2 | 0.25 | 77 | 0.12 | 1.5e-11 | -6.77 | 1.32e-11 | 0.64 | TRUE |
| Brain | LOC102547233 | gene expression | LOC102547233 | 0.4 | 1 | 0.37 | 2.4e-36 | 7.04 | 1.97e-12 | 0.06 | FALSE |
| Brain | LOC103693474 | gene expression | LOC103693474 | 0.07 | 1 | 0.06 | 1.7e-06 | 7.07 | 1.50e-12 | 0.07 | TRUE |
| Brain | LOC102549596 | isoform ratio | XR_005490526.1 | 0.19 | 1 | 0.08 | 5.9e-08 | 5.83 | 5.52e-09 | 0.05 | TRUE |
| Brain | LOC102549596 | isoform ratio | XR_357971.4 | 0.18 | 34 | 0.09 | 2.9e-08 | -5.72 | 1.07e-08 | 0.04 | FALSE |
| IL | LOC102547233 | gene expression | LOC102547233 | 0.82 | 1 | 0.46 | 1.1e-12 | 7.04 | 1.93e-12 | 0.06 | TRUE |
| LHb | LOC102547233 | gene expression | LOC102547233 | 0.36 | 74 | 0.15 | 2.2e-04 | 7.45 | 9.64e-14 | 0.58 | TRUE |
| NAcc | LOC102547233 | gene expression | LOC102547233 | 0.16 | 13 | 0.15 | 1.3e-16 | -7.11 | 1.17e-12 | 0 | FALSE |
| NAcc | LOC102549596 | isoform ratio | XR_357971.4 | 0.03 | 1 | 0.05 | 3.1e-06 | -5.67 | 1.39e-08 | 0.03 | FALSE |
| NAcc | LOC102549596 | intron excision ratio | chr10_98049905_98057892 | 0.05 | 1 | 0.03 | 2.6e-04 | -5.83 | 5.52e-09 | 0.03 | TRUE |
| OFC | LOC102547233 | gene expression | LOC102547233 | 0.39 | 1 | 0.15 | 1.6e-04 | 7.04 | 1.93e-12 | 0.05 | FALSE |
| PL | LOC102547233 | alternative TSS | XR_005490522.1 | 0.1 | 43 | 0.07 | 9.6e-08 | 6.74 | 1.58e-11 | 0.08 | FALSE |
| PL | LOC102547233 | alternative TSS | XR_594922.2 | 0.08 | 68 | 0.05 | 8.5e-06 | -6.68 | 2.46e-11 | 0.35 | FALSE |
| PL | LOC102547233 | gene expression | LOC102547233 | 0.66 | 61 | 0.46 | 3.0e-56 | 6.05 | 1.46e-09 | 0.03 | FALSE |
| PL | LOC102549521 | gene expression | LOC102549521 | 0.23 | 25 | 0.12 | 1.3e-13 | -5.34 | 9.39e-08 | 0.01 | FALSE |
| PL | LOC103693474 | gene expression | LOC103693474 | 0.11 | 2692 | 0.07 | 6.1e-08 | -5.28 | 1.26e-07 | 0 | FALSE |
| PL | LOC102549596 | intron excision ratio | chr10_98049905_98057892 | 0.04 | 1 | 0.01 | 1.0e-02 | -5.35 | 8.91e-08 | 0.03 | TRUE |