Hub : Traits : tautz: manual_spc15 : ←

chr10:92,191,656-96,071,622

Best TWAS P=6.138346e-09 · Best GWAS P=1.700519e-07 conditioned to NaN

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Wipi1	gene expression	ENSRNOG00000003827	0.38	0.20	blup	2914	0.23	5.9e-25	5.0	-5.8	6.1e-09	-0.81	0.42	0.58	TRUE
2	Adipose	Arsg	gene expression	ENSRNOG00000003931	0.28	0.18	lasso	39	0.19	2.6e-20	4.7	-5.5	4.9e-08	-0.73	0.46	0.54	FALSE
3	Adipose	Abca8a	intron excision ratio	chr10:95005301:95007077	0.02	0.00	blup	3105	0.01	1.5e-02	-4.1	-5.5	4.0e-08	-0.54	0.49	0.18	FALSE
4	Adipose	Abca9	intron excision ratio	chr10:95005301:95007077	0.02	0.00	blup	3137	0.01	1.6e-02	-4.1	-5.5	3.5e-08	-0.55	0.49	0.18	FALSE
5	BLA	Fam20a	gene expression	ENSRNOG00000003969	0.21	0.14	enet	171	0.16	7.8e-09	4.9	5.5	4.4e-08	0.62	0.41	0.59	FALSE
6	BLA	Prkar1a	gene expression	ENSRNOG00000049876	0.12	0.05	blup	2933	0.06	4.5e-04	4.9	-5.4	6.2e-08	-0.73	0.41	0.57	FALSE
7	BLA	NA	gene expression	ENSRNOG00000065020	0.14	0.05	blup	2869	0.11	1.4e-06	-3.2	-5.5	4.2e-08	-0.50	0.81	0.16	FALSE
8	BLA	Prkar1a	isoform ratio	ENSRNOT00000094613	0.17	0.08	blup	2933	0.11	2.1e-06	4.7	-5.5	3.6e-08	-0.86	0.50	0.49	FALSE
9	BLA	Fam20a	intron excision ratio	chr10:94656158:94696599	0.10	0.04	blup	2985	0.06	2.8e-04	-3.9	5.6	2.1e-08	0.61	0.82	0.15	FALSE
10	Brain	Apoh	gene expression	ENSRNOG00000003566	0.09	0.02	blup	2366	0.03	8.7e-04	4.7	-5.2	2.2e-07	-0.83	0.30	0.59	FALSE
11	Brain	AABR07030630.1	gene expression	ENSRNOG00000052124	0.22	0.13	blup	2263	0.16	1.5e-14	-4.0	5.5	4.6e-08	0.73	0.93	0.07	FALSE
12	Brain	Map2k6	mRNA stability	ENSRNOG00000004437	0.18	0.09	enet	35	0.22	5.2e-20	4.5	-5.6	2.1e-08	-0.50	0.60	0.40	TRUE
13	Eye	AABR07030630.1	gene expression	ENSRNOG00000052124	0.59	0.21	blup	2263	0.33	4.7e-06	4.8	5.5	3.0e-08	0.79	0.32	0.61	FALSE
14	IL	Abca8a	gene expression	ENSRNOG00000004147	0.24	0.07	blup	3103	0.13	6.3e-04	-4.6	-5.4	5.7e-08	-0.61	0.64	0.23	FALSE
15	IL	Abca8	mRNA stability	ENSRNOG00000004040	0.25	0.09	blup	3018	0.13	5.4e-04	4.6	-5.3	1.4e-07	-0.72	0.67	0.27	FALSE
16	LHb	Map2k6	gene expression	ENSRNOG00000004437	0.15	0.02	blup	2808	0.06	1.9e-02	-3.8	5.5	3.4e-08	0.53	0.43	0.22	FALSE
17	LHb	Abca8a	intron excision ratio	chr10:95005301:95007077	0.17	0.05	blup	3101	0.09	4.8e-03	4.7	-5.7	1.6e-08	-0.76	0.44	0.26	FALSE
18	Liver	Prkca	gene expression	ENSRNOG00000003491	0.65	0.15	lasso	52	0.26	2.0e-28	-4.3	-5.3	1.5e-07	-0.66	0.93	0.07	TRUE
19	Liver	Rgs9	gene expression	ENSRNOG00000003800	0.16	0.08	blup	2491	0.12	6.0e-13	4.9	5.4	7.7e-08	0.61	0.47	0.53	FALSE
20	Liver	NA	gene expression	ENSRNOG00000067823	0.52	0.13	lasso	52	0.22	8.8e-24	-4.0	-5.5	3.2e-08	-0.76	0.72	0.27	TRUE
21	NAcc	Apoh	gene expression	ENSRNOG00000003566	0.32	0.13	blup	2360	0.19	4.4e-05	4.6	-5.3	1.0e-07	-0.74	0.34	0.63	TRUE
22	NAcc	Wipi1	gene expression	ENSRNOG00000003827	0.46	0.19	lasso	7	0.29	3.7e-07	4.9	-5.2	1.8e-07	0.69	0.49	0.50	TRUE
23	NAcc2	Wipi1	gene expression	ENSRNOG00000003827	0.61	0.39	lasso	30	0.48	4.9e-29	4.9	-5.3	9.4e-08	-0.52	0.42	0.58	TRUE
24	NAcc2	AABR07030630.1	gene expression	ENSRNOG00000052124	0.09	0.01	blup	2263	0.06	3.4e-04	-4.0	5.4	8.5e-08	0.73	0.47	0.46	FALSE
25	NAcc2	Abca8	mRNA stability	ENSRNOG00000004040	0.11	0.02	blup	3022	0.04	5.1e-03	-4.6	-5.3	1.1e-07	-0.55	0.75	0.23	FALSE
26	OFC	Wipi1	gene expression	ENSRNOG00000003827	0.31	0.00	blup	2907	0.02	1.0e-01	4.9	-5.3	1.3e-07	-0.60	0.47	0.45	FALSE
27	OFC	Map2k6	gene expression	ENSRNOG00000004437	0.44	0.22	blup	2809	0.31	4.1e-08	-4.6	5.1	3.2e-07	0.52	0.61	0.38	TRUE
28	PL	Wipi1	gene expression	ENSRNOG00000003827	0.50	0.12	blup	2907	0.19	2.3e-05	-3.9	-5.3	1.2e-07	-0.53	0.48	0.46	FALSE
29	PL	Abca8a	gene expression	ENSRNOG00000004147	0.42	0.19	blup	3103	0.28	2.5e-07	4.5	-5.6	2.0e-08	-0.68	0.64	0.34	TRUE
30	PL2	Prkar1a	alternative TSS	ENSRNOT00000119272	0.35	0.17	enet	77	0.22	6.4e-12	-4.1	5.4	7.7e-08	0.68	0.85	0.14	FALSE
31	PL2	Wipi1	gene expression	ENSRNOG00000003827	0.41	0.30	lasso	16	0.35	4.1e-20	4.9	-5.3	1.3e-07	-0.71	0.42	0.58	FALSE
32	PL2	Map2k6	mRNA stability	ENSRNOG00000004437	0.11	0.02	blup	2814	0.07	1.3e-04	4.6	-5.3	1.4e-07	-0.42	0.54	0.31	FALSE
33	PL2	Abca9	mRNA stability	ENSRNOG00000059326	0.06	0.00	blup	3139	0.04	1.7e-03	-4.1	5.5	3.4e-08	0.55	0.49	0.14	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.