Best TWAS P=2.643196e-08 · Best GWAS P=1.484284e-06 conditioned to 0.9094585
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | BLA | Icam2 | isoform ratio | ENSRNOT00000035474 | 0.09 | 0.05 | enet | 29 | 0.05 | 0.00089 | 4.1 | 5.6 | 2.6e-08 | 0.85 | 0.43 | 0.55 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.