Best TWAS P=7.599883e-08 · Best GWAS P=0.0002091998 conditioned to 1.345238e-06
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Liver | Grhpr | mRNA stability | ENSRNOG00000012794 | 0.02 | 0.02 | enet | 86 | 0.04 | 4.9e-05 | -1.6 | 5.4 | 7.6e-08 | 0.19 | 0.26 | 0.02 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.