Best TWAS P=1.475546e-07 · Best GWAS P=5.779253e-08 conditioned to 1
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | OFC | Ca8 | gene expression | ENSRNOG00000005669 | 0.81 | 0.55 | top1 | 1 | 0.55 | 1.3e-15 | -5.1 | -5.1 | 3.4e-07 | 0.94 | 0.25 | 0.75 | FALSE |
| 2 | PL | Ca8 | gene expression | ENSRNOG00000005669 | 0.55 | 0.22 | enet | 23 | 0.25 | 2.2e-19 | -5.0 | -5.3 | 1.5e-07 | 0.94 | 0.23 | 0.76 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.