chr3:141,582,335-143,940,882

Trait: Length with tail

Best TWAS P = 9.69e-10 · Best GWAS P= 2.45e-09 conditioned to 1.40e-08

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose Plcb4 alternative TSS NM_024353.2 0.08 1407 0.01 1.0e-02 -5.55 2.82e-08 0.36 FALSE
Adipose Plcb4 gene expression Plcb4 0.13 1 0.09 2.4e-10 -5.25 1.55e-07 0.59 FALSE
Adipose Plcb4 isoform ratio XM_063283133.1 0.05 1 0.06 9.7e-08 5.32 1.02e-07 0.67 TRUE
Adipose Plcb4 isoform ratio XM_063283135.1 0.03 4 0.04 7.8e-05 -5.48 4.32e-08 0.58 TRUE
Adipose Plcb4 intron excision ratio chr3_143493493_143559809 0.65 56 0.53 1.0e-68 -5.24 1.62e-07 0.54 FALSE
Adipose Plcb4 mRNA stability Plcb4 0.06 28 0.05 1.6e-06 -5.4 6.74e-08 0.53 FALSE
BLA Plcb4 alternative TSS XM_039104319.2 0.12 1407 0.05 1.0e-03 6.11 9.69e-10 0.51 TRUE
BLA Plcb4 alternative TSS XM_039104319.2 0.09 1407 0.05 1.5e-03 6.03 1.62e-09 0.52 FALSE
BLA Plcb4 gene expression Plcb4 0.31 52 0.2 8.5e-11 -5.34 9.31e-08 0.63 FALSE
BLA Plcb4 intron excision ratio chr3_143493493_143559809 0.05 47 0.03 9.5e-03 -6.07 1.25e-09 0.24 FALSE
Brain Plcb4 alternative TSS XM_039104319.2 0.57 48 0.39 1.2e-38 5.38 7.43e-08 0.65 FALSE
Brain Plcb4 alternative TSS XM_039104319.2 0.56 41 0.42 8.7e-42 5.38 7.58e-08 0.67 TRUE
Brain Plcb4 alternative TSS XM_039104325.2 0.23 1 0.2 9.5e-19 -5.22 1.81e-07 0.55 FALSE
Brain Lamp5 gene expression Lamp5 0.07 29 0.03 6.2e-04 5.68 1.32e-08 0.07 FALSE
Brain Plcb4 gene expression Plcb4 0.56 1 0.5 9.7e-53 -5.21 1.90e-07 0.54 FALSE
Brain Plcb4 isoform ratio XM_006235085.5 0.21 98 0.14 4.0e-13 -5.53 3.15e-08 0.58 FALSE
Brain Plcb1 intron excision ratio chr3_143138850_143150657 0.03 1107 0.03 1.3e-03 5.37 7.72e-08 0.25 FALSE
Brain Plcb1 intron excision ratio chr3_143138850_143222448 0.02 1107 0.01 2.3e-02 -5.53 3.13e-08 0.33 FALSE
Brain Plcb4 intron excision ratio chr3_143493493_143559809 0.44 44 0.25 1.3e-23 -5.25 1.55e-07 0.55 FALSE
Brain Plcb4 intron excision ratio chr3_143517457_143559809 0.02 1407 0.02 3.1e-03 -5.27 1.40e-07 0.44 FALSE
Brain Plcb4 intron excision ratio chr3_143523533_143559809 0.5 1407 0.32 2.6e-30 5.56 2.64e-08 0.57 FALSE
IC Plcb4 alternative TSS XM_039104319.2 0.43 1 0.33 2.0e-14 5.29 1.22e-07 0.64 FALSE
IC Plcb4 isoform ratio XM_006235085.5 0.12 1 0.06 1.6e-03 -5.3 1.14e-07 0.05 FALSE
IC Plcb4 intron excision ratio chr3_143493493_143559809 0.33 9 0.32 3.9e-14 -5.29 1.25e-07 0.64 TRUE
IL Plcb1 gene expression Plcb1 0.22 1107 0.11 1.3e-03 5.36 8.12e-08 0.27 FALSE
IL Plcb4 gene expression Plcb4 0.56 1 0.3 6.7e-08 -5.29 1.22e-07 0.32 FALSE
LHb Plcb4 gene expression Plcb4 0.31 1 0.14 2.9e-04 -5.22 1.81e-07 0.06 FALSE
Liver Plcb1 gene expression Plcb1 0.05 33 0.04 6.2e-05 -5.21 1.91e-07 0.24 FALSE
Liver Hao1 mRNA stability Hao1 0.39 47 0.27 9.0e-30 5.25 1.52e-07 0.14 TRUE
NAcc Plcb4 alternative TSS XM_039104319.2 0.08 1 0.06 2.7e-09 5.22 1.75e-07 0.56 FALSE
NAcc Plcb4 alternative TSS XM_039104319.2 0.06 1 0.05 6.6e-08 5.23 1.70e-07 0.56 FALSE
NAcc Plcb4 gene expression Plcb4 0.11 24 0.14 1.0e-20 -5.44 5.31e-08 0.65 FALSE
NAcc Plcb1 intron excision ratio chr3_143138850_143222448 0.04 1 0.03 6.2e-05 -5.62 1.91e-08 0.78 FALSE
NAcc Plcb4 intron excision ratio chr3_143493493_143559809 0.1 20 0.06 8.1e-09 -5.27 1.36e-07 0.54 FALSE
OFC Plcb4 gene expression Plcb4 0.52 238 0.46 1.6e-12 -5.46 4.79e-08 0.61 FALSE
PL Plcb4 alternative TSS XM_039104317.2 0.03 1 0.03 1.4e-04 -5.27 1.37e-07 0.06 FALSE
PL Plcb4 alternative TSS XM_039104319.2 0.14 5 0.11 1.4e-11 5.35 8.98e-08 0.57 FALSE
PL Plcb4 alternative TSS XM_039104317.2 0.02 1 0.02 1.8e-03 -5.22 1.75e-07 0.04 FALSE
PL Plcb4 alternative TSS XM_039104319.2 0.16 8 0.12 1.7e-13 5.48 4.28e-08 0.58 TRUE
PL Plcb4 alternative TSS XM_039104325.2 0.05 1 0.03 1.8e-04 -5.22 1.81e-07 0.08 FALSE
PL Plcb1 intron excision ratio chr3_143138850_143150657 0.02 1107 0.01 9.9e-03 5.44 5.30e-08 0.26 FALSE
PL Plcb4 intron excision ratio chr3_143493493_143559809 0.16 1407 0.09 3.3e-10 -6.02 1.73e-09 0.57 FALSE
pVTA Plcb4 alternative TSS XM_039104325.2 0.1 14 0.13 1.7e-10 -5.42 5.97e-08 0.63 FALSE
pVTA Plcb4 alternative TSS XM_039104319.2 0.38 46 0.39 2.3e-33 5.4 6.67e-08 0.67 FALSE
pVTA Plcb4 alternative TSS XM_039104325.2 0.13 65 0.13 2.2e-10 -5.37 7.89e-08 0.63 FALSE
pVTA Plcb4 gene expression Plcb4 0.1 1 0.06 1.5e-05 -5.29 1.20e-07 0.43 FALSE
pVTA Plcb4 isoform ratio XM_063283134.1 0.08 1407 0.08 2.8e-07 6.07 1.26e-09 0.62 FALSE
pVTA Plcb4 intron excision ratio chr3_143517457_143559809 0.02 1 0.02 1.1e-02 -5.33 1.00e-07 0.05 FALSE
pVTA Plcb4 intron excision ratio chr3_143523533_143559809 0.25 66 0.29 1.3e-23 5.38 7.54e-08 0.66 FALSE