Best TWAS P = 1.04e-07 · Best GWAS P= 1.67e-07 conditioned to 1.00e+00
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Brain | Podxl | mRNA stability | Podxl | 0.05 | 56 | 0.03 | 4.5e-04 | 5.25 | 1.51e-07 | 0.86 | FALSE |
| Liver | Copg2 | intron excision ratio | chr4_60394334_60414271 | 0.04 | 2097 | 0.03 | 2.4e-04 | -5.27 | 1.35e-07 | 0.62 | FALSE |
| Liver | Mest | mRNA stability | Mest | 0.07 | 7 | 0.09 | 4.2e-10 | 5.32 | 1.04e-07 | 0.67 | TRUE |