Hub : Traits : Left kidney weight : ← →

chr5:148,559,083-150,187,748

Trait: Left kidney weight

Best TWAS P=1.067407e-09 · Best GWAS P=1.067407e-09 conditioned to 0.1451897

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Ece1	alternative TSS	ENSRNOT00000102078	0.03	0.03	blup	920	0.03	4.3e-04	-5.3	5.3	1.3e-07	-0.89	0.54	0.44	FALSE
2	Adipose	Alpl	gene expression	ENSRNOG00000013954	0.08	0.11	blup	995	0.11	1.3e-12	-5.3	5.3	1.3e-07	-0.89	0.57	0.43	FALSE
3	Adipose	Ece1	gene expression	ENSRNOG00000014241	0.02	0.02	top1	1	0.03	8.2e-04	-5.7	-5.7	9.7e-09	0.89	0.04	0.10	FALSE
4	Adipose	AABR07073181.1	gene expression	ENSRNOG00000021437	0.06	0.09	top1	1	0.09	4.5e-10	-5.3	5.3	1.4e-07	-0.88	0.66	0.34	FALSE
5	Adipose	Ldlrad2	gene expression	ENSRNOG00000033503	0.02	0.02	top1	1	0.02	1.5e-03	-5.2	5.2	1.7e-07	-0.88	0.04	0.03	FALSE
6	Adipose	Usp48	isoform ratio	ENSRNOT00000031855	0.21	0.34	top1	1	0.34	1.6e-38	-5.3	5.3	1.3e-07	-0.88	0.65	0.35	FALSE
7	Adipose	Usp48	isoform ratio	ENSRNOT00000077933	0.19	0.26	lasso	15	0.26	1.1e-28	-5.3	-5.3	1.0e-07	0.90	0.59	0.41	FALSE
8	Adipose	Ece1	isoform ratio	ENSRNOT00000102078	0.04	0.03	blup	920	0.03	1.2e-04	-5.3	5.3	1.3e-07	-0.89	0.54	0.45	FALSE
9	Adipose	AABR07073181.1	isoform ratio	ENSRNOT00000039341	0.02	0.00	blup	1371	0.01	2.6e-02	-5.3	5.2	1.9e-07	-0.86	0.46	0.36	FALSE
10	Adipose	AABR07073181.1	isoform ratio	ENSRNOT00000098496	0.22	0.33	lasso	28	0.33	3.1e-37	-5.3	5.3	1.4e-07	-0.89	0.59	0.41	FALSE
11	Adipose	AABR07073181.1	isoform ratio	ENSRNOT00000105209	0.23	0.35	blup	1371	0.36	6.4e-42	-5.3	-5.3	1.3e-07	0.88	0.61	0.39	FALSE
12	Adipose	NA	isoform ratio	ENSRNOT00000120115	0.04	0.01	blup	1249	0.03	5.6e-04	-5.3	-5.3	1.3e-07	0.82	0.26	0.69	FALSE
13	Adipose	Usp48	intron excision ratio	chr5:149800971:149810309	0.05	0.03	blup	1259	0.04	3.7e-05	-5.7	-5.2	2.4e-07	0.82	0.34	0.64	FALSE
14	Adipose	Usp48	intron excision ratio	chr5:149810429:149811690	0.05	0.04	blup	1259	0.04	2.4e-05	-5.7	5.1	3.0e-07	-0.81	0.33	0.66	FALSE
15	Adipose	Usp48	intron excision ratio	chr5:149833625:149836154	0.25	0.39	lasso	25	0.40	1.9e-47	-5.3	-5.5	4.5e-08	0.92	0.62	0.38	FALSE
16	Adipose	Usp48	intron excision ratio	chr5:149833826:149836154	0.26	0.39	lasso	27	0.40	1.9e-47	-5.3	5.5	4.6e-08	-0.92	0.62	0.38	FALSE
17	Adipose	Ece1	intron excision ratio	chr5:150126242:150133824	0.03	0.03	top1	1	0.03	3.8e-04	-5.3	-5.3	1.4e-07	0.89	0.05	0.04	FALSE
18	Adipose	Ece1	intron excision ratio	chr5:150133272:150133824	0.03	0.03	top1	1	0.03	4.0e-04	-5.3	5.3	1.4e-07	-0.89	0.05	0.04	FALSE
19	Adipose	AABR07073181.1	intron excision ratio	chr5:149716950:149718780	0.18	0.22	blup	1371	0.23	6.6e-25	-5.2	5.2	2.3e-07	-0.88	0.56	0.44	FALSE
20	Adipose	AABR07073181.1	intron excision ratio	chr5:149716950:149719207	0.26	0.36	blup	1371	0.37	1.1e-43	-5.2	-5.2	1.6e-07	0.89	0.60	0.40	FALSE
21	Adipose	AABR07073181.1	intron excision ratio	chr5:149718830:149719207	0.22	0.32	top1	1	0.32	5.0e-36	-5.3	5.3	1.4e-07	-0.88	0.66	0.34	FALSE
22	BLA	Ece1	gene expression	ENSRNOG00000014241	0.14	0.09	blup	920	0.10	6.0e-06	-5.3	-5.3	1.2e-07	0.89	0.52	0.47	FALSE
23	BLA	Eif4g3	gene expression	ENSRNOG00000014368	0.07	0.03	blup	807	0.04	5.9e-03	-5.3	-5.3	1.4e-07	0.89	0.32	0.40	FALSE
24	BLA	Usp48	isoform ratio	ENSRNOT00000031855	0.20	0.21	top1	1	0.21	1.0e-11	-5.3	5.3	1.2e-07	-0.89	0.63	0.37	FALSE
25	BLA	Usp48	isoform ratio	ENSRNOT00000077933	0.19	0.25	top1	1	0.25	1.4e-13	-5.3	-5.3	1.1e-07	0.89	0.61	0.39	FALSE
26	BLA	Usp48	intron excision ratio	chr5:149833625:149836154	0.50	0.40	blup	1259	0.41	1.3e-23	-5.3	-5.3	9.1e-08	0.88	0.55	0.45	FALSE
27	BLA	Usp48	intron excision ratio	chr5:149833826:149836154	0.52	0.40	blup	1259	0.42	6.4e-24	-5.3	5.3	9.1e-08	-0.88	0.54	0.46	FALSE
28	BLA	Usp48	mRNA stability	ENSRNOG00000013602	0.12	0.14	top1	1	0.14	4.4e-08	-5.3	5.3	1.2e-07	-0.89	0.59	0.35	FALSE
29	Brain	Rap1gap	alternative polyA	ENSRNOT00000046802	0.05	0.08	top1	1	0.08	3.2e-08	-5.9	-5.9	3.4e-09	0.89	0.05	0.95	FALSE
30	Brain	Rap1gap	alternative polyA	ENSRNOT00000116365	0.05	0.08	top1	1	0.08	6.0e-08	-5.9	5.9	3.4e-09	-0.89	0.05	0.95	FALSE
31	Brain	Alpl	gene expression	ENSRNOG00000013954	0.07	0.08	lasso	3	0.09	2.2e-08	-5.9	5.9	4.4e-09	-0.90	0.53	0.47	FALSE
32	Brain	Usp48	isoform ratio	ENSRNOT00000031855	0.33	0.44	enet	441	0.48	1.1e-50	-5.2	5.3	9.3e-08	-0.90	0.61	0.39	FALSE
33	Brain	Usp48	isoform ratio	ENSRNOT00000077933	0.32	0.46	lasso	9	0.48	6.5e-50	-5.9	-5.9	3.4e-09	0.89	0.54	0.46	FALSE
34	Brain	Usp48	isoform ratio	ENSRNOT00000112285	0.09	0.12	blup	1259	0.13	3.9e-12	-5.2	-5.3	1.3e-07	0.86	0.60	0.40	FALSE
35	Brain	Usp48	intron excision ratio	chr5:149833625:149836154	0.43	0.54	enet	444	0.58	1.7e-65	-5.2	-5.3	1.2e-07	0.89	0.61	0.39	FALSE
36	Brain	Usp48	intron excision ratio	chr5:149833826:149836154	0.43	0.54	lasso	21	0.58	5.5e-65	-5.2	5.3	1.3e-07	-0.89	0.61	0.39	FALSE
37	Brain	Rap1gap	intron excision ratio	chr5:149933815:149934662	0.02	0.02	top1	1	0.02	9.9e-03	-5.9	-5.9	3.5e-09	0.89	0.04	0.08	FALSE
38	Brain	Rap1gap	mRNA stability	ENSRNOG00000013825	0.09	0.11	blup	1124	0.12	4.3e-11	-5.2	-5.2	1.8e-07	0.87	0.60	0.40	FALSE
39	Eye	Wnt4	gene expression	ENSRNOG00000013166	0.56	0.00	top1	1	0.00	2.9e-01	-5.9	5.9	3.8e-09	-0.87	0.08	0.06	FALSE
40	Eye	Usp48	gene expression	ENSRNOG00000013602	0.67	0.04	blup	1259	0.09	1.8e-02	-5.6	5.4	7.5e-08	-0.89	0.32	0.36	FALSE
41	Eye	Usp48	isoform ratio	ENSRNOT00000031855	0.68	0.13	blup	1259	0.16	2.0e-03	-5.9	5.3	9.1e-08	-0.89	0.42	0.43	FALSE
42	Eye	Usp48	isoform ratio	ENSRNOT00000077933	0.67	0.00	blup	1259	0.17	1.4e-03	-5.6	-5.3	1.4e-07	0.84	0.43	0.46	FALSE
43	Eye	Usp48	intron excision ratio	chr5:149833625:149836154	0.49	0.01	blup	1259	0.08	2.5e-02	-5.9	-5.4	8.4e-08	0.88	0.28	0.28	FALSE
44	Eye	Usp48	intron excision ratio	chr5:149833826:149836154	0.49	0.02	blup	1259	0.05	5.6e-02	-5.9	5.3	9.6e-08	-0.89	0.27	0.28	FALSE
45	IL	Usp48	gene expression	ENSRNOG00000013602	0.11	0.11	top1	1	0.11	1.5e-03	-5.4	5.4	5.2e-08	-0.89	0.07	0.06	FALSE
46	IL	Rap1gap	gene expression	ENSRNOG00000013825	0.11	0.12	top1	1	0.12	9.4e-04	-5.3	5.3	1.2e-07	-0.89	0.06	0.06	FALSE
47	IL	Usp48	isoform ratio	ENSRNOT00000031855	0.21	0.19	top1	1	0.19	2.1e-05	-5.3	5.3	1.2e-07	-0.89	0.10	0.07	FALSE
48	IL	Usp48	isoform ratio	ENSRNOT00000077933	0.29	0.29	lasso	3	0.31	3.0e-08	-5.3	-5.3	1.2e-07	0.89	0.47	0.53	FALSE
49	IL	Usp48	intron excision ratio	chr5:149833625:149836154	0.42	0.45	lasso	5	0.47	8.6e-13	-5.3	-5.3	1.3e-07	0.89	0.46	0.54	FALSE
50	IL	Usp48	intron excision ratio	chr5:149833826:149836154	0.42	0.45	lasso	5	0.46	1.1e-12	-5.3	5.3	1.3e-07	-0.89	0.47	0.54	FALSE
51	LHb	Rap1gap	gene expression	ENSRNOG00000013825	0.28	0.29	top1	1	0.29	1.3e-07	-5.3	5.3	1.3e-07	-0.89	0.26	0.15	FALSE
52	LHb	Zbtb40	gene expression	ENSRNOG00000022039	0.21	0.18	blup	1221	0.20	1.8e-05	-5.3	-5.1	3.5e-07	0.77	0.22	0.70	FALSE
53	LHb	Usp48	isoform ratio	ENSRNOT00000031855	0.27	0.26	blup	1253	0.29	1.1e-07	-4.0	5.3	1.0e-07	-0.89	0.47	0.53	FALSE
54	LHb	Usp48	intron excision ratio	chr5:149833625:149836154	0.45	0.51	top1	1	0.51	4.0e-14	-5.3	-5.3	1.3e-07	0.88	0.65	0.35	FALSE
55	LHb	Usp48	intron excision ratio	chr5:149833826:149836154	0.43	0.49	blup	1253	0.49	1.6e-13	-5.3	5.3	9.9e-08	-0.88	0.47	0.54	FALSE
56	Liver	Rap1gap	gene expression	ENSRNOG00000013825	0.20	0.20	enet	194	0.22	1.1e-23	-5.3	5.9	4.7e-09	-0.92	0.49	0.51	FALSE
57	Liver	Alpl	gene expression	ENSRNOG00000013954	0.17	0.24	blup	995	0.26	2.0e-28	-5.2	5.2	1.8e-07	-0.87	0.57	0.43	FALSE
58	Liver	Ece1	gene expression	ENSRNOG00000014241	0.07	0.02	top1	1	0.02	1.5e-03	-5.9	-5.9	3.7e-09	0.89	0.04	0.31	FALSE
59	Liver	AABR07073181.1	gene expression	ENSRNOG00000021437	0.04	0.03	top1	1	0.03	7.2e-04	-5.3	5.3	1.4e-07	-0.88	0.16	0.09	FALSE
60	Liver	Usp48	isoform ratio	ENSRNOT00000031855	0.06	0.11	top1	1	0.11	5.8e-12	-5.3	5.3	1.4e-07	-0.88	0.66	0.34	FALSE
61	Liver	Usp48	isoform ratio	ENSRNOT00000077933	0.18	0.22	top1	1	0.22	1.5e-23	-5.2	-5.2	1.7e-07	0.88	0.70	0.30	FALSE
62	Liver	Usp48	intron excision ratio	chr5:149833625:149836154	0.30	0.41	top1	1	0.41	4.4e-49	-5.2	-5.2	1.7e-07	0.88	0.70	0.30	FALSE
63	Liver	Usp48	intron excision ratio	chr5:149833826:149836154	0.28	0.40	top1	1	0.40	6.3e-47	-5.2	5.2	1.7e-07	-0.88	0.70	0.30	FALSE
64	NAcc	Rap1gap	alternative TSS	ENSRNOT00000046802	0.22	0.21	top1	1	0.21	1.7e-15	-5.3	5.3	1.2e-07	-0.89	0.63	0.37	FALSE
65	NAcc	Usp48	gene expression	ENSRNOG00000013602	0.07	0.05	blup	1257	0.06	2.2e-05	-5.4	-5.1	2.9e-07	0.87	0.47	0.53	FALSE
66	NAcc	Rap1gap	gene expression	ENSRNOG00000013825	0.04	0.03	top1	1	0.03	5.1e-03	-5.8	-5.8	5.0e-09	0.89	0.04	0.16	FALSE
67	NAcc	Ece1	gene expression	ENSRNOG00000014241	0.19	0.09	blup	920	0.10	9.3e-08	-5.2	-5.2	1.8e-07	0.89	0.53	0.47	FALSE
68	NAcc	Usp48	isoform ratio	ENSRNOT00000077933	0.30	0.30	lasso	29	0.34	1.9e-26	-5.2	-5.2	1.7e-07	0.89	0.63	0.37	FALSE
69	NAcc	Usp48	isoform ratio	ENSRNOT00000112285	0.05	0.03	blup	1257	0.03	2.9e-03	-4.6	-5.1	3.1e-07	0.87	0.44	0.44	FALSE
70	NAcc	Rap1gap	isoform ratio	ENSRNOT00000046802	0.10	0.10	lasso	1	0.10	4.6e-08	-5.3	5.3	1.2e-07	-0.89	0.51	0.49	FALSE
71	NAcc	Rap1gap	isoform ratio	ENSRNOT00000098228	0.14	0.13	lasso	1	0.14	1.5e-10	-5.3	-5.3	1.2e-07	0.89	0.52	0.48	FALSE
72	NAcc	Usp48	intron excision ratio	chr5:149833625:149836154	0.50	0.53	lasso	49	0.56	6.4e-50	-5.2	-5.3	1.5e-07	0.89	0.63	0.37	FALSE
73	NAcc	Usp48	intron excision ratio	chr5:149833826:149836154	0.42	0.51	lasso	42	0.55	4.0e-48	-5.2	5.3	1.5e-07	-0.89	0.63	0.37	FALSE
74	NAcc	Rap1gap	intron excision ratio	chr5:149914780:149920646	0.16	0.15	top1	1	0.15	4.1e-11	-5.2	5.2	2.4e-07	-0.89	0.76	0.23	FALSE
75	NAcc	Rap1gap	intron excision ratio	chr5:149918394:149920646	0.17	0.15	top1	1	0.15	3.3e-11	-5.2	-5.2	2.4e-07	0.89	0.76	0.23	FALSE
76	NAcc	Usp48	mRNA stability	ENSRNOG00000013602	0.04	0.03	top1	1	0.03	2.1e-03	-6.1	6.1	1.1e-09	-0.89	0.04	0.22	TRUE
77	NAcc	Rap1gap	mRNA stability	ENSRNOG00000013825	0.07	0.07	blup	1123	0.07	5.5e-06	-6.0	-5.2	2.4e-07	0.85	0.40	0.60	FALSE
78	OFC	Rap1gap	gene expression	ENSRNOG00000013825	0.15	0.03	blup	1120	0.05	2.9e-02	-5.2	5.2	2.1e-07	-0.86	0.34	0.35	FALSE
79	OFC	Ece1	gene expression	ENSRNOG00000014241	0.41	0.08	blup	917	0.11	1.4e-03	-5.3	-5.2	2.1e-07	0.88	0.37	0.42	FALSE
80	OFC	Usp48	isoform ratio	ENSRNOT00000031855	0.21	0.20	top1	1	0.20	1.3e-05	-5.3	5.3	1.3e-07	-0.89	0.12	0.08	FALSE
81	OFC	Usp48	isoform ratio	ENSRNOT00000077933	0.21	0.25	top1	1	0.25	1.3e-06	-5.3	-5.3	1.3e-07	0.89	0.16	0.10	FALSE
82	OFC	Usp48	intron excision ratio	chr5:149833625:149836154	0.47	0.41	top1	1	0.41	6.6e-11	-5.3	-5.3	1.1e-07	0.89	0.56	0.36	FALSE
83	OFC	Usp48	intron excision ratio	chr5:149833826:149836154	0.47	0.42	top1	1	0.42	4.5e-11	-5.3	5.3	1.1e-07	-0.89	0.55	0.35	FALSE
84	OFC	Eif4g3	mRNA stability	ENSRNOG00000014368	0.20	0.12	top1	1	0.12	1.1e-03	-5.3	-5.3	1.4e-07	0.89	0.05	0.06	FALSE
85	PL	Usp48	gene expression	ENSRNOG00000013602	0.08	0.09	top1	1	0.09	3.3e-07	-6.1	6.1	1.1e-09	-0.89	0.02	0.98	FALSE
86	PL	Rap1gap	gene expression	ENSRNOG00000013825	0.06	0.04	top1	1	0.04	1.1e-03	-5.8	5.8	6.7e-09	-0.89	0.04	0.07	FALSE
87	PL	Ece1	gene expression	ENSRNOG00000014241	0.08	0.04	blup	920	0.05	8.5e-05	-4.7	-5.3	1.3e-07	0.89	0.51	0.48	FALSE
88	PL	Usp48	isoform ratio	ENSRNOT00000031855	0.16	0.23	top1	1	0.23	8.4e-18	-5.3	5.3	1.0e-07	-0.89	0.59	0.41	FALSE
89	PL	Usp48	isoform ratio	ENSRNOT00000077933	0.27	0.33	lasso	37	0.36	3.2e-28	-5.2	-5.2	1.7e-07	0.89	0.60	0.40	FALSE
90	PL	Usp48	intron excision ratio	chr5:149833625:149836154	0.41	0.43	lasso	50	0.47	1.9e-39	-5.2	-5.2	1.6e-07	0.89	0.62	0.38	FALSE
91	PL	Usp48	intron excision ratio	chr5:149833826:149836154	0.37	0.40	enet	191	0.44	7.0e-37	-5.2	5.2	1.7e-07	-0.89	0.62	0.38	FALSE
92	PL	Usp48	mRNA stability	ENSRNOG00000013602	0.07	0.03	blup	1257	0.05	1.1e-04	-5.3	5.3	1.4e-07	-0.86	0.54	0.46	FALSE
93	PL	Rap1gap	mRNA stability	ENSRNOG00000013825	0.05	0.05	top1	1	0.05	6.4e-05	-5.8	-5.8	6.7e-09	0.88	0.07	0.52	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.