chr5:148,559,083-150,187,748

Trait: Left kidney weight

Best TWAS P=1.07e-09 · Best GWAS P=1.07e-09 conditioned to 1.45e-01

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose Ece1 alternative TSS ENSRNOT00000102078 0.03 920 0.03 4.3e-04 5.28 1.31e-07 0.44 FALSE
Adipose Alpl gene expression ENSRNOG00000013954 0.08 995 0.11 1.3e-12 5.28 1.31e-07 0.43 FALSE
Adipose Ece1 gene expression ENSRNOG00000014241 0.02 1 0.03 8.2e-04 -5.74 9.70e-09 0.1 FALSE
Adipose AABR07073181.1 gene expression ENSRNOG00000021437 0.06 1 0.09 4.5e-10 5.26 1.40e-07 0.34 FALSE
Adipose Ldlrad2 gene expression ENSRNOG00000033503 0.02 1 0.02 1.5e-03 5.23 1.68e-07 0.03 FALSE
Adipose Usp48 isoform ratio ENSRNOT00000031855 0.21 1 0.34 1.6e-38 5.28 1.32e-07 0.35 FALSE
Adipose Usp48 isoform ratio ENSRNOT00000077933 0.19 15 0.26 1.1e-28 -5.33 9.97e-08 0.41 FALSE
Adipose Ece1 isoform ratio ENSRNOT00000102078 0.04 920 0.03 1.2e-04 5.28 1.30e-07 0.45 FALSE
Adipose AABR07073181.1 isoform ratio ENSRNOT00000039341 0.02 1371 0.01 2.6e-02 5.21 1.86e-07 0.36 FALSE
Adipose AABR07073181.1 isoform ratio ENSRNOT00000098496 0.22 28 0.33 3.1e-37 5.26 1.41e-07 0.41 FALSE
Adipose AABR07073181.1 isoform ratio ENSRNOT00000105209 0.23 1371 0.36 6.4e-42 -5.28 1.32e-07 0.39 FALSE
Adipose ENSRNOG00000069740 isoform ratio ENSRNOT00000120115 0.04 1249 0.03 5.6e-04 -5.27 1.33e-07 0.69 FALSE
Adipose Usp48 intron excision ratio chr5:149800971:149810309 0.05 1259 0.04 3.7e-05 -5.17 2.36e-07 0.64 FALSE
Adipose Usp48 intron excision ratio chr5:149810429:149811690 0.05 1259 0.04 2.4e-05 5.12 3.04e-07 0.66 FALSE
Adipose Usp48 intron excision ratio chr5:149833625:149836154 0.25 25 0.4 1.9e-47 -5.47 4.49e-08 0.38 FALSE
Adipose Usp48 intron excision ratio chr5:149833826:149836154 0.26 27 0.4 1.9e-47 5.47 4.56e-08 0.38 FALSE
Adipose Ece1 intron excision ratio chr5:150126242:150133824 0.03 1 0.03 3.8e-04 -5.26 1.44e-07 0.04 FALSE
Adipose Ece1 intron excision ratio chr5:150133272:150133824 0.03 1 0.03 4.0e-04 5.26 1.44e-07 0.04 FALSE
Adipose AABR07073181.1 intron excision ratio chr5:149716950:149718780 0.18 1371 0.23 6.6e-25 5.17 2.29e-07 0.44 FALSE
Adipose AABR07073181.1 intron excision ratio chr5:149716950:149719207 0.26 1371 0.37 1.1e-43 -5.24 1.57e-07 0.4 FALSE
Adipose AABR07073181.1 intron excision ratio chr5:149718830:149719207 0.22 1 0.32 5.0e-36 5.26 1.40e-07 0.34 FALSE
BLA Ece1 gene expression ENSRNOG00000014241 0.14 920 0.1 6.0e-06 -5.29 1.24e-07 0.47 FALSE
BLA Eif4g3 gene expression ENSRNOG00000014368 0.07 807 0.04 5.9e-03 -5.27 1.38e-07 0.4 FALSE
BLA Usp48 isoform ratio ENSRNOT00000031855 0.2 1 0.21 1.0e-11 5.29 1.21e-07 0.37 FALSE
BLA Usp48 isoform ratio ENSRNOT00000077933 0.19 1 0.25 1.4e-13 -5.31 1.09e-07 0.39 FALSE
BLA Usp48 intron excision ratio chr5:149833625:149836154 0.5 1259 0.41 1.3e-23 -5.34 9.06e-08 0.45 FALSE
BLA Usp48 intron excision ratio chr5:149833826:149836154 0.52 1259 0.42 6.4e-24 5.34 9.07e-08 0.46 FALSE
BLA Usp48 mRNA stability ENSRNOG00000013602 0.12 1 0.14 4.4e-08 5.29 1.20e-07 0.35 FALSE
Brain Rap1gap alternative polyA ENSRNOT00000046802 0.05 1 0.08 3.2e-08 -5.91 3.39e-09 0.95 FALSE
Brain Rap1gap alternative polyA ENSRNOT00000116365 0.05 1 0.08 6.0e-08 5.91 3.39e-09 0.95 FALSE
Brain Alpl gene expression ENSRNOG00000013954 0.07 3 0.09 2.2e-08 5.87 4.43e-09 0.47 FALSE
Brain Usp48 isoform ratio ENSRNOT00000031855 0.33 441 0.48 1.1e-50 5.34 9.27e-08 0.39 FALSE
Brain Usp48 isoform ratio ENSRNOT00000077933 0.32 9 0.48 6.5e-50 -5.91 3.41e-09 0.46 FALSE
Brain Usp48 isoform ratio ENSRNOT00000112285 0.09 1259 0.13 3.9e-12 -5.28 1.29e-07 0.4 FALSE
Brain Usp48 intron excision ratio chr5:149833625:149836154 0.43 444 0.58 1.7e-65 -5.29 1.23e-07 0.39 FALSE
Brain Usp48 intron excision ratio chr5:149833826:149836154 0.43 21 0.58 5.5e-65 5.27 1.35e-07 0.39 FALSE
Brain Rap1gap intron excision ratio chr5:149933815:149934662 0.02 1 0.02 9.9e-03 -5.9 3.54e-09 0.08 FALSE
Brain Rap1gap mRNA stability ENSRNOG00000013825 0.09 1124 0.12 4.3e-11 -5.22 1.83e-07 0.4 FALSE
Eye Wnt4 gene expression ENSRNOG00000013166 0.56 1 0 2.9e-01 5.89 3.79e-09 0.06 FALSE
Eye Usp48 gene expression ENSRNOG00000013602 0.67 1259 0.09 1.8e-02 5.38 7.53e-08 0.36 FALSE
Eye Usp48 isoform ratio ENSRNOT00000031855 0.68 1259 0.16 2.0e-03 5.34 9.05e-08 0.43 FALSE
Eye Usp48 isoform ratio ENSRNOT00000077933 0.67 1259 0.17 1.4e-03 -5.26 1.45e-07 0.46 FALSE
Eye Usp48 intron excision ratio chr5:149833625:149836154 0.49 1259 0.08 2.5e-02 -5.36 8.45e-08 0.28 FALSE
Eye Usp48 intron excision ratio chr5:149833826:149836154 0.49 1259 0.05 5.6e-02 5.33 9.57e-08 0.28 FALSE
IL Usp48 gene expression ENSRNOG00000013602 0.11 1 0.11 1.5e-03 5.44 5.25e-08 0.06 FALSE
IL Rap1gap gene expression ENSRNOG00000013825 0.11 1 0.12 9.4e-04 5.29 1.21e-07 0.06 FALSE
IL Usp48 isoform ratio ENSRNOT00000031855 0.21 1 0.19 2.1e-05 5.29 1.23e-07 0.07 FALSE
IL Usp48 isoform ratio ENSRNOT00000077933 0.29 3 0.31 3.0e-08 -5.29 1.22e-07 0.53 FALSE
IL Usp48 intron excision ratio chr5:149833625:149836154 0.42 5 0.47 8.6e-13 -5.28 1.28e-07 0.54 FALSE
IL Usp48 intron excision ratio chr5:149833826:149836154 0.42 5 0.46 1.1e-12 5.27 1.34e-07 0.54 FALSE
LHb Rap1gap gene expression ENSRNOG00000013825 0.28 1 0.29 1.3e-07 5.28 1.31e-07 0.15 FALSE
LHb Zbtb40 gene expression ENSRNOG00000022039 0.21 1221 0.2 1.8e-05 -5.09 3.51e-07 0.7 FALSE
LHb Usp48 isoform ratio ENSRNOT00000031855 0.27 1253 0.29 1.1e-07 5.32 1.03e-07 0.53 FALSE
LHb Usp48 intron excision ratio chr5:149833625:149836154 0.45 1 0.51 4.0e-14 -5.28 1.32e-07 0.35 FALSE
LHb Usp48 intron excision ratio chr5:149833826:149836154 0.43 1253 0.49 1.6e-13 5.33 9.91e-08 0.54 FALSE
Liver Rap1gap gene expression ENSRNOG00000013825 0.2 194 0.22 1.1e-23 5.86 4.67e-09 0.51 FALSE
Liver Alpl gene expression ENSRNOG00000013954 0.17 995 0.26 2.0e-28 5.22 1.80e-07 0.43 FALSE
Liver Ece1 gene expression ENSRNOG00000014241 0.07 1 0.02 1.5e-03 -5.9 3.66e-09 0.31 FALSE
Liver AABR07073181.1 gene expression ENSRNOG00000021437 0.04 1 0.03 7.2e-04 5.26 1.44e-07 0.09 FALSE
Liver Usp48 isoform ratio ENSRNOT00000031855 0.06 1 0.11 5.8e-12 5.27 1.36e-07 0.34 FALSE
Liver Usp48 isoform ratio ENSRNOT00000077933 0.18 1 0.22 1.5e-23 -5.23 1.68e-07 0.3 FALSE
Liver Usp48 intron excision ratio chr5:149833625:149836154 0.3 1 0.41 4.4e-49 -5.23 1.68e-07 0.3 FALSE
Liver Usp48 intron excision ratio chr5:149833826:149836154 0.28 1 0.4 6.3e-47 5.23 1.68e-07 0.3 FALSE
NAcc Rap1gap alternative TSS ENSRNOT00000046802 0.22 1 0.21 1.7e-15 5.29 1.23e-07 0.37 FALSE
NAcc Usp48 gene expression ENSRNOG00000013602 0.07 1257 0.06 2.2e-05 -5.13 2.93e-07 0.53 FALSE
NAcc Rap1gap gene expression ENSRNOG00000013825 0.04 1 0.03 5.1e-03 -5.85 5.04e-09 0.16 FALSE
NAcc Ece1 gene expression ENSRNOG00000014241 0.19 920 0.1 9.3e-08 -5.21 1.84e-07 0.47 FALSE
NAcc Usp48 isoform ratio ENSRNOT00000077933 0.3 29 0.34 1.9e-26 -5.23 1.66e-07 0.37 FALSE
NAcc Usp48 isoform ratio ENSRNOT00000112285 0.05 1257 0.03 2.9e-03 -5.12 3.07e-07 0.44 FALSE
NAcc Rap1gap isoform ratio ENSRNOT00000046802 0.1 1 0.1 4.6e-08 5.29 1.23e-07 0.49 FALSE
NAcc Rap1gap isoform ratio ENSRNOT00000098228 0.14 1 0.14 1.5e-10 -5.29 1.23e-07 0.48 FALSE
NAcc Usp48 intron excision ratio chr5:149833625:149836154 0.5 49 0.56 6.4e-50 -5.25 1.49e-07 0.37 FALSE
NAcc Usp48 intron excision ratio chr5:149833826:149836154 0.42 42 0.55 4.0e-48 5.25 1.51e-07 0.37 FALSE
NAcc Rap1gap intron excision ratio chr5:149914780:149920646 0.16 1 0.15 4.1e-11 5.17 2.38e-07 0.23 FALSE
NAcc Rap1gap intron excision ratio chr5:149918394:149920646 0.17 1 0.15 3.3e-11 -5.17 2.38e-07 0.23 FALSE
NAcc Usp48 mRNA stability ENSRNOG00000013602 0.04 1 0.03 2.1e-03 6.1 1.07e-09 0.22 TRUE
NAcc Rap1gap mRNA stability ENSRNOG00000013825 0.07 1123 0.07 5.5e-06 -5.17 2.40e-07 0.6 FALSE
OFC Rap1gap gene expression ENSRNOG00000013825 0.15 1120 0.05 2.9e-02 5.19 2.13e-07 0.35 FALSE
OFC Ece1 gene expression ENSRNOG00000014241 0.41 917 0.11 1.4e-03 -5.19 2.07e-07 0.42 FALSE
OFC Usp48 isoform ratio ENSRNOT00000031855 0.21 1 0.2 1.3e-05 5.28 1.32e-07 0.08 FALSE
OFC Usp48 isoform ratio ENSRNOT00000077933 0.21 1 0.25 1.3e-06 -5.28 1.31e-07 0.1 FALSE
OFC Usp48 intron excision ratio chr5:149833625:149836154 0.47 1 0.41 6.6e-11 -5.31 1.11e-07 0.36 FALSE
OFC Usp48 intron excision ratio chr5:149833826:149836154 0.47 1 0.42 4.5e-11 5.31 1.11e-07 0.35 FALSE
OFC Eif4g3 mRNA stability ENSRNOG00000014368 0.2 1 0.12 1.1e-03 -5.26 1.44e-07 0.06 FALSE
PL Usp48 gene expression ENSRNOG00000013602 0.08 1 0.09 3.3e-07 6.1 1.07e-09 0.98 FALSE
PL Rap1gap gene expression ENSRNOG00000013825 0.06 1 0.04 1.1e-03 5.8 6.70e-09 0.07 FALSE
PL Ece1 gene expression ENSRNOG00000014241 0.08 920 0.05 8.5e-05 -5.28 1.27e-07 0.48 FALSE
PL Usp48 isoform ratio ENSRNOT00000031855 0.16 1 0.23 8.4e-18 5.32 1.03e-07 0.41 FALSE
PL Usp48 isoform ratio ENSRNOT00000077933 0.27 37 0.36 3.2e-28 -5.23 1.67e-07 0.4 FALSE
PL Usp48 intron excision ratio chr5:149833625:149836154 0.41 50 0.47 1.9e-39 -5.24 1.61e-07 0.38 FALSE
PL Usp48 intron excision ratio chr5:149833826:149836154 0.37 191 0.44 7.0e-37 5.23 1.73e-07 0.38 FALSE
PL Usp48 mRNA stability ENSRNOG00000013602 0.07 1257 0.05 1.1e-04 5.27 1.38e-07 0.46 FALSE
PL Rap1gap mRNA stability ENSRNOG00000013825 0.05 1 0.05 6.4e-05 -5.8 6.70e-09 0.52 FALSE