Best TWAS P=1.44e-08 · Best GWAS P=7.60e-08 conditioned to 4.06e-01
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Adipose | AABR07029596.1 | alternative TSS | ENSRNOT00000058907 | 0.05 | 1 | 0.04 | 1.9e-05 | 5.31 | 1.10e-07 | 0.83 | FALSE |
| Adipose | AABR07029596.1 | alternative TSS | ENSRNOT00000114988 | 0.05 | 1 | 0.04 | 2.0e-05 | -5.31 | 1.10e-07 | 0.83 | FALSE |
| Adipose | AABR07029596.1 | isoform ratio | ENSRNOT00000058907 | 0.03 | 1 | 0.03 | 5.0e-04 | 5.2 | 1.98e-07 | 0.3 | FALSE |
| Adipose | AABR07029596.1 | isoform ratio | ENSRNOT00000114988 | 0.03 | 7 | 0.03 | 7.3e-04 | -5.2 | 2.00e-07 | 0.64 | FALSE |
| BLA | Septin8 | intron excision ratio | chr10:37701775:37712417 | 0.06 | 14 | 0.05 | 1.8e-03 | 5.19 | 2.12e-07 | 0.65 | FALSE |
| BLA | Shroom1 | mRNA stability | ENSRNOG00000007431 | 0.18 | 1 | 0.05 | 8.2e-04 | 5.3 | 1.15e-07 | 0.35 | FALSE |
| Brain | Aff4 | mRNA stability | ENSRNOG00000006965 | 0.06 | 26 | 0.01 | 4.4e-02 | 5.67 | 1.44e-08 | 0.62 | TRUE |
| Liver | AABR07029596.1 | gene expression | ENSRNOG00000046195 | 0.05 | 1 | 0.02 | 1.4e-03 | -5.3 | 1.15e-07 | 0.34 | FALSE |
| Liver | ENSRNOG00000069239 | gene expression | ENSRNOG00000069239 | 0.02 | 1 | 0.01 | 2.0e-02 | -5.3 | 1.15e-07 | 0.07 | FALSE |