Hub : Traits : Left kidney weight : ← : →

chr5:153,715,252-155,471,100

Trait: Left kidney weight

Best TWAS P = 3.10e-10 · Best GWAS P= 3.45e-10 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Ece1	alternative TSS	XM_006239276.5	0.02	929	0.01	6.8e-03	5.64	1.71e-08	0.39	FALSE
Adipose	Alpl	gene expression	Alpl	0.08	1	0.12	1.0e-13	5.6	2.10e-08	0.37	FALSE
Adipose	Hspg2	gene expression	Hspg2	0.05	1	0.08	3.2e-09	5.6	2.10e-08	0.37	FALSE
Adipose	Ldlrad2	gene expression	Ldlrad2	0.04	1294	0.05	1.1e-06	5.57	2.55e-08	0.47	FALSE
Adipose	Ece1	isoform ratio	NM_053596.2	0.02	929	0.01	9.8e-03	5.58	2.42e-08	0.4	FALSE
Adipose	Ece1	isoform ratio	XM_006239276.5	0.02	929	0.01	1.0e-02	5.65	1.63e-08	0.39	FALSE
Adipose	Ece1	isoform ratio	XM_063288516.1	0.03	929	0.03	2.9e-04	-5.65	1.64e-08	0.49	FALSE
Adipose	Hspg2	isoform ratio	NM_001427438.1	0.27	57	0.39	1.5e-46	-5.66	1.52e-08	0.41	FALSE
Adipose	Hspg2	isoform ratio	XM_063287775.1	0.27	1376	0.39	2.5e-46	5.76	8.66e-09	0.41	FALSE
Adipose	Ece1	intron excision ratio	chr5_155409587_155417171	0.03	49	0.03	5.2e-04	-5.49	3.96e-08	0.46	FALSE
Adipose	Ece1	intron excision ratio	chr5_155416616_155417171	0.03	49	0.03	4.9e-04	5.49	3.99e-08	0.46	FALSE
Adipose	Hspg2	intron excision ratio	chr5_155000329_155002158	0.18	1376	0.22	1.7e-24	5.35	9.01e-08	0.47	FALSE
Adipose	Hspg2	intron excision ratio	chr5_155000329_155002585	0.26	1376	0.38	1.5e-44	-5.56	2.71e-08	0.44	FALSE
Adipose	Hspg2	intron excision ratio	chr5_155002208_155002585	0.22	45	0.32	2.0e-36	5.56	2.66e-08	0.44	FALSE
Adipose	LOC134487019	intron excision ratio	chr5_155334432_155360200	0.03	19	0.03	6.4e-04	-5.9	3.70e-09	0.54	FALSE
Adipose	Usp48	intron excision ratio	chr5_155084347_155093685	0.04	1261	0.02	2.8e-03	-6.15	7.74e-10	0.54	FALSE
Adipose	Usp48	intron excision ratio	chr5_155093805_155095066	0.05	1261	0.02	1.6e-03	6.14	8.50e-10	0.53	FALSE
BLA	Ece1	gene expression	Ece1	0.14	929	0.1	8.2e-06	-5.6	2.12e-08	0.51	FALSE
BLA	Usp48	gene expression	Usp48	0.11	1	0.03	7.8e-03	5.41	6.19e-08	0.04	FALSE
Brain	Rap1gap	alternative polyA	XM_017593410.3	0.02	1	0.04	1.1e-04	5.61	2.06e-08	0.05	FALSE
Brain	Rap1gap	alternative polyA	XM_063287788.1	0.02	1	0.04	5.3e-05	-5.61	2.06e-08	0.06	FALSE
Brain	Zbtb40	alternative polyA	XM_039110414.2	0.03	1	0.02	3.4e-03	-5.63	1.84e-08	0.04	FALSE
Brain	Zbtb40	alternative polyA	XM_063288073.1	0.03	1276	0.02	3.3e-03	6.12	9.25e-10	0.42	FALSE
Brain	Zbtb40	alternative polyA	XM_039110414.2	0.03	1276	0.02	7.7e-03	-6.29	3.10e-10	0.66	TRUE
Brain	Zbtb40	alternative polyA	XM_063288073.1	0.02	1276	0.02	3.5e-03	6.11	9.96e-10	0.41	FALSE
Brain	Eif4g3	alternative TSS	XM_017593294.3	0.08	809	0.07	1.8e-07	-5.56	2.66e-08	0.56	FALSE
Brain	Eif4g3	alternative TSS	XM_039109672.2	0.08	809	0.07	5.4e-07	5.5	3.72e-08	0.55	FALSE
Brain	Eif4g3	alternative TSS	XM_017593294.3	0.05	809	0.05	3.8e-05	-5.55	2.83e-08	0.55	FALSE
Brain	Eif4g3	alternative TSS	XM_039109672.2	0.11	809	0.1	1.8e-09	5.55	2.90e-08	0.56	FALSE
Brain	Alpl	gene expression	Alpl	0.07	1	0.1	3.7e-09	6.22	5.03e-10	0.96	FALSE
Brain	Usp48	gene expression	Usp48	0.06	1261	0.09	8.0e-09	5.78	7.47e-09	0.47	FALSE
Brain	Eif4g3	isoform ratio	XM_039109671.2	0.06	34	0.04	8.2e-05	5.57	2.58e-08	0.56	TRUE
Brain	Eif4g3	isoform ratio	XM_063287469.1	0.05	809	0.05	3.9e-05	5.55	2.88e-08	0.55	FALSE
Brain	Rap1gap	isoform ratio	XM_063287788.1	0.07	1142	0.09	1.4e-08	-5.62	1.89e-08	0.48	FALSE
Brain	Zbtb40	isoform ratio	XM_063288073.1	0.02	1276	0.01	4.6e-02	6.21	5.40e-10	0.45	FALSE
Brain	Rap1gap	mRNA stability	Rap1gap	0.14	49	0.21	1.4e-19	-5.59	2.30e-08	0.46	FALSE
Eye	Rap1gap	gene expression	Rap1gap	0.62	1142	0.13	4.8e-03	5.73	1.03e-08	0.29	FALSE
Eye	Usp48	gene expression	Usp48	0.67	1261	0.15	2.6e-03	6.01	1.85e-09	0.37	FALSE
Eye	Usp48	mRNA stability	Usp48	0.52	1261	0.21	4.3e-04	-5.9	3.59e-09	0.34	FALSE
IC	Cdc42	alternative polyA	NM_171994.5	0.09	1	0.07	7.1e-04	5.66	1.54e-08	0.05	FALSE
IC	Cdc42	alternative polyA	XM_008764287.4	0.1	1	0.07	5.0e-04	-5.66	1.54e-08	0.05	FALSE
IC	Ece1	gene expression	Ece1	0.2	929	0.17	1.6e-07	-5.7	1.20e-08	0.44	FALSE
IC	Hspg2	gene expression	Hspg2	0.06	1	0.08	2.3e-04	-5.83	5.40e-09	0.07	FALSE
IC	Usp48	gene expression	Usp48	0.07	1261	0.07	5.3e-04	5.54	2.95e-08	0.55	FALSE
IC	Cdc42	isoform ratio	NM_171994.5	0.09	1	0.07	6.1e-04	5.66	1.54e-08	0.05	FALSE
IL	Usp48	gene expression	Usp48	0.17	1	0.16	1.5e-04	6.09	1.13e-09	0.13	FALSE
IL	Zbtb40	gene expression	Zbtb40	0.22	1276	0.26	7.4e-07	-5.8	6.63e-09	0.03	FALSE
LHb	C1qc	gene expression	C1qc	0.33	1152	0.29	1.0e-07	-5.36	8.38e-08	0.55	TRUE
LHb	Rap1gap	gene expression	Rap1gap	0.25	1142	0.27	4.6e-07	5.62	1.90e-08	0.49	FALSE
LHb	Zbtb40	mRNA stability	Zbtb40	0.39	1	0.1	2.0e-03	-5.71	1.13e-08	0.06	FALSE
Liver	Wnt4	alternative TSS	NM_053402.2	0.02	1	0	2.7e-01	5.62	1.96e-08	0.03	FALSE
Liver	Alpl	gene expression	Alpl	0.16	1006	0.25	3.5e-27	5.78	7.66e-09	0.44	FALSE
Liver	Ece1	gene expression	Ece1	0.04	929	0.03	3.4e-04	-5.55	2.89e-08	0.54	FALSE
Liver	Hspg2	gene expression	Hspg2	0.03	2	0.03	1.0e-04	5.54	3.02e-08	0.46	FALSE
Liver	Zbtb40	gene expression	Zbtb40	0.09	27	0.07	3.0e-08	-5.22	1.77e-07	0	FALSE
NAcc	Rap1gap	alternative TSS	XM_063287781.1	0.19	1142	0.28	3.3e-43	-5.41	6.15e-08	0.41	FALSE
NAcc	Rap1gap	alternative TSS	XM_063287781.1	0.2	1142	0.3	7.9e-47	-5.45	5.03e-08	0.41	FALSE
NAcc	Rap1gap	alternative TSS	XM_063287786.1	0.06	1142	0.08	1.1e-12	5.59	2.33e-08	0.42	FALSE
NAcc	Zbtb40	alternative TSS	NM_001191871.1	0.02	35	0.02	1.2e-03	5.46	4.69e-08	0.21	TRUE
NAcc	Alpl	gene expression	Alpl	0.03	1006	0.03	2.1e-05	-5.58	2.39e-08	0.43	FALSE
NAcc	Ece1	gene expression	Ece1	0.15	75	0.2	3.2e-29	-5.68	1.32e-08	0.52	FALSE
NAcc	Rap1gap	gene expression	Rap1gap	0.12	18	0.1	1.4e-15	-5.68	1.37e-08	0.41	FALSE
NAcc	Rap1gap	isoform ratio	XM_017593412.3	0.17	1142	0.26	6.0e-40	-5.41	6.25e-08	0.39	FALSE
NAcc	Rap1gap	isoform ratio	XM_017593413.2	0.13	1142	0.15	7.9e-22	5.24	1.63e-07	0.42	FALSE
NAcc	Rap1gap	intron excision ratio	chr5_155177288_155198058	0.01	1142	0.01	3.9e-03	5.45	5.16e-08	0.35	FALSE
NAcc	Rap1gap	intron excision ratio	chr5_155198151_155204017	0.18	1142	0.27	2.4e-41	5.5	3.88e-08	0.38	FALSE
NAcc	Rap1gap	intron excision ratio	chr5_155201765_155204017	0.19	1142	0.28	4.5e-42	-5.53	3.22e-08	0.39	FALSE
NAcc	Rap1gap	mRNA stability	Rap1gap	0.09	16	0.12	2.6e-18	-5.44	5.38e-08	0.41	FALSE
PL	Ece1	gene expression	Ece1	0.09	929	0.07	3.4e-08	-5.49	4.07e-08	0.58	FALSE
PL	Usp48	gene expression	Usp48	0.09	1	0.13	7.1e-14	5.63	1.76e-08	0.41	FALSE
PL	Hspg2	isoform ratio	XM_063287775.1	0.02	1376	0.01	1.5e-02	5.9	3.56e-09	0.26	FALSE
PL	Rap1gap	mRNA stability	Rap1gap	0.11	1142	0.11	3.1e-12	-5.69	1.24e-08	0.57	FALSE
pVTA	Ece1	alternative TSS	NM_053596.2	0.05	929	0.04	1.5e-04	-5.48	4.36e-08	0.41	FALSE
pVTA	Ece1	alternative TSS	XM_063288516.1	0.04	929	0.03	1.1e-03	-5.63	1.83e-08	0.41	FALSE
pVTA	Alpl	gene expression	Alpl	0.03	1	0.03	1.5e-03	5.62	1.96e-08	0.04	FALSE
pVTA	Ece1	gene expression	Ece1	0.24	929	0.22	6.1e-18	-5.74	9.61e-09	0.42	FALSE
pVTA	Ece1	isoform ratio	XM_006239276.5	0.04	929	0.03	3.3e-03	5.71	1.11e-08	0.49	FALSE
pVTA	Rap1gap	intron excision ratio	chr5_155217183_155218030	0.03	1142	0.03	3.9e-03	-5.44	5.31e-08	0.42	FALSE