Best TWAS P=1.81667e-07 · Best GWAS P=8.922668e-08 conditioned to 1
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Fign | gene expression | ENSRNOG00000004679 | 0.10 | 0.07 | blup | 2436 | 0.08 | 4.9e-09 | 5.2 | -5.2 | 2.1e-07 | -0.95 | 0.48 | 0.52 | FALSE |
| 2 | Liver | Fign | gene expression | ENSRNOG00000004679 | 0.05 | 0.03 | blup | 2436 | 0.04 | 1.2e-05 | 4.7 | -5.2 | 1.8e-07 | -0.93 | 0.62 | 0.37 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.