chr3:65,822,892-71,118,704

Trait: Epididymis fat weight

Best TWAS P = 3.71e-10 · Best GWAS P= 1.88e-10 conditioned to 1.00e+00

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose Ifih1 alternative polyA XM_063284355.1 0.07 1648 0.04 6.4e-05 5.23 1.68e-07 0.54 FALSE
Adipose Fign alternative TSS XM_063283273.1 0.04 2493 0.02 2.7e-03 6.08 1.20e-09 0.48 FALSE
Adipose Tank alternative TSS XM_006234273.5 0.04 1 0.02 2.8e-03 -5.56 2.65e-08 0.17 FALSE
Adipose Tank alternative TSS XM_006234273.5 0.04 1 0.02 3.6e-03 -5.57 2.52e-08 0.15 FALSE
Adipose Fign gene expression Fign 0.11 1 0.09 2.0e-10 -6.27 3.71e-10 0.87 TRUE
Adipose Grb14 gene expression Grb14 0.33 35 0.23 1.1e-24 -5.44 5.34e-08 0.18 FALSE
Adipose Tank gene expression Tank 0.21 1462 0.13 5.5e-14 -5.32 1.02e-07 0.83 FALSE
Adipose Ifih1 isoform ratio XM_039105671.2 0.06 90 0.06 2.4e-07 5.35 8.94e-08 0.42 FALSE
Adipose Tank isoform ratio XM_006234274.4 0.08 1 0.03 2.9e-04 5.56 2.65e-08 0.68 FALSE
Adipose Ifih1 mRNA stability Ifih1 0.13 1648 0.14 4.3e-15 -5.22 1.79e-07 0.38 FALSE
BLA Cobll1 gene expression Cobll1 0.08 41 0.05 1.3e-03 5.6 2.10e-08 0.53 FALSE
BLA Gca isoform ratio NM_001106483.4 0.38 1622 0.37 6.5e-21 5.36 8.42e-08 0.5 FALSE
BLA Gca isoform ratio XM_039104486.2 0.46 1622 0.44 1.4e-25 -5.32 1.02e-07 0.43 FALSE
BLA Gca intron excision ratio chr3_67734856_67736020 0.3 1 0.21 1.6e-11 5.35 8.76e-08 0.72 FALSE
BLA Gca intron excision ratio chr3_67734856_67736716 0.34 1 0.28 3.6e-15 -5.35 8.76e-08 0.72 FALSE
BLA Grb14 mRNA stability Grb14 0.37 38 0.38 1.5e-21 5.5 3.90e-08 0.24 FALSE
Brain Ifih1 alternative TSS XM_039105671.2 0.06 1 0.06 4.6e-06 5.3 1.16e-07 0.56 FALSE
Brain Cobll1 gene expression Cobll1 0.05 2442 0.05 1.6e-05 5.69 1.29e-08 0.78 FALSE
Brain Grb14 gene expression Grb14 0.62 390 0.6 4.9e-70 -5.73 9.93e-09 0.24 FALSE
Brain Ifih1 gene expression Ifih1 0.14 5 0.22 9.6e-21 -5.29 1.21e-07 0.37 TRUE
Brain LOC108350383 gene expression LOC108350383 0.04 1 0.05 2.7e-05 -5.23 1.72e-07 0.05 FALSE
Brain Gca isoform ratio NM_001106483.4 0.19 11 0.32 1.5e-30 5.4 6.81e-08 0.38 FALSE
Brain Grb14 isoform ratio NM_031623.2 0.06 2786 0.05 2.9e-05 5.33 9.62e-08 0.62 TRUE
Brain Grb14 intron excision ratio chr3_69997205_70000169 0.02 2786 0.01 2.1e-02 5.65 1.64e-08 0.44 FALSE
Brain LOC108350383 intron excision ratio chr3_68231297_68231717 0.08 1304 0.08 6.6e-08 -5.56 2.72e-08 0.39 FALSE
Brain LOC108350383 intron excision ratio chr3_68231369_68231717 0.04 1304 0.03 1.2e-03 5.48 4.24e-08 0.37 FALSE
Brain Gca mRNA stability Gca 0.12 1 0.15 4.2e-14 -5.23 1.72e-07 0.57 FALSE
IC Grb14 alternative TSS XM_039105749.2 0.1 2786 0.02 3.5e-02 -5.52 3.39e-08 0.48 FALSE
IC Cobll1 gene expression Cobll1 0.09 2442 0.01 8.1e-02 5.22 1.81e-07 0.48 FALSE
IC Kcnh7 gene expression Kcnh7 0.12 1304 0.1 5.3e-05 5.23 1.66e-07 0.16 FALSE
IC Tank gene expression Tank 0.15 1 0.06 2.2e-03 5.36 8.34e-08 0.07 FALSE
IC Grb14 isoform ratio XM_039105749.2 0.08 2786 0.01 1.1e-01 -5.53 3.26e-08 0.39 FALSE
IC LOC108350383 intron excision ratio chr3_68231297_68231717 0.13 1 0.08 2.6e-04 -5.46 4.90e-08 0.1 FALSE
IC Kcnh7 mRNA stability Kcnh7 0.1 1304 0.04 7.4e-03 5.28 1.30e-07 0.33 TRUE
IL Fign alternative TSS XM_063283273.1 0.2 1 0.11 1.4e-03 5.21 1.93e-07 0.05 FALSE
IL Fign gene expression Fign 0.18 2493 0.07 8.6e-03 -5.97 2.31e-09 0.31 FALSE
IL Gca isoform ratio XM_039104486.2 0.35 1622 0.19 2.6e-05 -5.26 1.46e-07 0.44 FALSE
IL Gca intron excision ratio chr3_67734856_67736020 0.29 1622 0.09 3.5e-03 5.22 1.75e-07 0.42 FALSE
IL Gca intron excision ratio chr3_67734856_67736716 0.29 1622 0.09 3.3e-03 -5.22 1.82e-07 0.41 FALSE
IL Gca mRNA stability Gca 0.26 1 0.13 5.3e-04 -5.26 1.43e-07 0.06 FALSE
IL Grb14 mRNA stability Grb14 0.73 26 0.43 1.2e-11 5.44 5.34e-08 0.25 FALSE
IL Tank mRNA stability Tank 0.3 1462 0.06 1.4e-02 5.32 1.03e-07 0.46 TRUE
LHb Grb14 gene expression Grb14 0.34 1 0.22 5.3e-06 -5.75 8.76e-09 0.1 FALSE
LHb Cobll1 mRNA stability Cobll1 0.22 1 0.04 3.2e-02 -5.48 4.18e-08 0.05 FALSE
LHb Grb14 mRNA stability Grb14 0.4 1 0.25 9.7e-07 5.32 1.06e-07 0.06 FALSE
Liver LOC134486366 alternative TSS XR_010065195.1 0.05 1 0.04 1.7e-05 -5.4 6.55e-08 0.03 FALSE
Liver LOC134486366 alternative TSS XR_010065197.1 0.05 1 0.04 2.9e-05 5.4 6.55e-08 0.03 FALSE
Liver Fign gene expression Fign 0.06 1 0.05 3.9e-06 -6.11 9.72e-10 0.59 FALSE
Liver Slc38a11 gene expression Slc38a11 0.07 1 0.03 9.8e-05 5.82 5.94e-09 0.24 FALSE
Liver Grb14 mRNA stability Grb14 0.39 12 0.4 2.1e-47 5.33 9.88e-08 0.19 FALSE
NAcc Tank alternative polyA XM_006234273.5 0.05 10 0.02 4.5e-04 5.43 5.60e-08 0.78 FALSE
NAcc Tank alternative polyA XM_039104358.2 0.12 1 0.06 2.1e-09 -5.39 7.23e-08 0.8 FALSE
NAcc Fign alternative TSS XM_008761889.4 0.01 1 0.02 5.7e-04 -5.55 2.85e-08 0.03 FALSE
NAcc Grb14 alternative TSS NM_031623.2 0.06 2786 0.06 3.7e-09 5.61 2.01e-08 0.76 FALSE
NAcc Cobll1 gene expression Cobll1 0.03 5 0.05 2.4e-08 6.09 1.14e-09 0.82 TRUE
NAcc Fign gene expression Fign 0.04 26 0.05 4.5e-08 6.24 4.43e-10 0.56 FALSE
NAcc LOC134486367 gene expression LOC134486367 0.12 18 0.14 2.5e-20 5.91 3.50e-09 0.69 FALSE
NAcc Cobll1 isoform ratio XM_039106332.2 0.02 1 0.02 1.3e-03 -5.95 2.75e-09 0.21 FALSE
NAcc Grb14 isoform ratio NM_031623.2 0.08 2786 0.06 3.5e-10 5.42 6.00e-08 0.78 FALSE
NAcc LOC134486367 isoform ratio XR_010065198.1 0.07 2343 0.06 6.1e-10 5.3 1.18e-07 0.51 FALSE
NAcc Tank isoform ratio XM_039104358.2 0.1 19 0.06 2.8e-09 -5.31 1.08e-07 0.82 FALSE
NAcc Grb14 intron excision ratio chr3_70017203_70090309 0.04 2786 0.03 8.2e-06 5.43 5.54e-08 0.72 FALSE
NAcc Tank intron excision ratio chr3_66571619_66573417 0.04 1 0.03 3.8e-05 -5.51 3.57e-08 0.83 FALSE
NAcc Tank intron excision ratio chr3_66573535_66574956 0.05 5 0.03 5.2e-05 -5.44 5.24e-08 0.81 FALSE
NAcc Slc4a10 mRNA stability Slc4a10 0.02 1 0.03 8.7e-05 -5.26 1.45e-07 0.16 FALSE
OFC Fap gene expression Fap 0.14 1732 0.11 1.7e-03 5.27 1.39e-07 0.34 FALSE
OFC Fign gene expression Fign 0.33 2493 0.18 3.9e-05 -6.08 1.21e-09 0.38 FALSE
OFC Grb14 gene expression Grb14 0.33 55 0.2 1.7e-05 -5.57 2.59e-08 0.57 FALSE
OFC Gca isoform ratio NM_001106483.4 0.55 1622 0.38 5.3e-10 5.28 1.26e-07 0.42 FALSE
OFC Gca isoform ratio XM_039104486.2 0.54 1622 0.37 7.6e-10 -5.29 1.21e-07 0.42 TRUE
OFC Gca intron excision ratio chr3_67734856_67736020 0.41 1 0.38 4.7e-10 5.26 1.43e-07 0.52 FALSE
OFC Gca intron excision ratio chr3_67734856_67736716 0.46 1 0.41 8.5e-11 -5.26 1.43e-07 0.56 FALSE
OFC Gca mRNA stability Gca 0.2 1 0.17 6.7e-05 -5.46 4.80e-08 0.13 FALSE
PL Fap gene expression Fap 0.05 1732 0.05 3.3e-06 5.26 1.41e-07 0.45 FALSE
PL Gca gene expression Gca 0.08 22 0.1 1.1e-10 -5.44 5.43e-08 0.45 FALSE
PL LOC108350383 gene expression LOC108350383 0.03 1304 0.03 8.5e-04 -5.22 1.76e-07 0.18 FALSE
PL Tank gene expression Tank 0.04 1 0.03 3.1e-04 5.46 4.80e-08 0.2 FALSE
PL Gca isoform ratio XM_063283272.1 0.03 1622 0.03 2.2e-04 5.24 1.59e-07 0.43 FALSE
PL Slc4a10 intron excision ratio chr3_67354934_67357618 0.05 1 0.05 6.9e-06 -5.32 1.03e-07 0.52 FALSE
PL Slc4a10 intron excision ratio chr3_67357734_67358508 0.03 1 0.03 8.5e-04 5.25 1.55e-07 0.06 FALSE
pVTA Cobll1 gene expression Cobll1 0.08 1 0.07 1.2e-06 5.57 2.62e-08 0.5 FALSE
pVTA Grb14 gene expression Grb14 0.6 117 0.39 1.8e-33 -5.34 9.34e-08 0.8 TRUE
pVTA Gca isoform ratio NM_001106483.4 0.04 1622 0.01 1.9e-02 5.29 1.19e-07 0.42 FALSE
pVTA Gca isoform ratio XM_039104486.2 0.07 1622 0.07 2.2e-06 -5.22 1.81e-07 0.41 FALSE
pVTA Gca intron excision ratio chr3_67734856_67736020 0.05 1622 0.04 4.9e-04 5.22 1.79e-07 0.42 FALSE
pVTA Gca intron excision ratio chr3_67734856_67736716 0.09 1622 0.09 5.6e-08 -5.22 1.82e-07 0.4 FALSE
pVTA LOC108350383 intron excision ratio chr3_68231369_68231717 0.03 1304 0.02 6.5e-03 5.55 2.92e-08 0.41 FALSE
pVTA Grb14 mRNA stability Grb14 0.19 2786 0.23 1.3e-18 5.38 7.44e-08 0.22 FALSE