Hub : Traits : Epididymis fat weight : ← →

chr1:257,530,505-260,518,987

Trait: Epididymis fat weight

Best TWAS P=5.441885e-32 · Best GWAS P=2.027242e-32 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Dennd10	gene expression	ENSRNOG00000010230	0.03	0.03	top1	1	0.03	2.5e-04	-8.9	-8.9	7.5e-19	0.69	0.24	0.02	FALSE
2	Adipose	Prdx3	gene expression	ENSRNOG00000010958	0.19	0.22	lasso	34	0.22	1.6e-23	-7.1	-7.3	4.0e-13	0.53	1.00	0.00	FALSE
3	Adipose	Grk5	gene expression	ENSRNOG00000011439	0.17	0.20	lasso	24	0.22	8.6e-24	-9.7	9.6	1.3e-21	-0.73	1.00	0.00	FALSE
4	Adipose	Ces2c	gene expression	ENSRNOG00000036571	0.11	0.03	blup	596	0.07	2.3e-08	-5.1	6.8	9.7e-12	-0.56	0.98	0.01	FALSE
5	Adipose	NA	gene expression	ENSRNOG00000065260	0.17	0.12	top1	1	0.12	3.2e-13	-6.1	-6.1	1.3e-09	0.61	1.00	0.00	FALSE
6	Adipose	NA	gene expression	ENSRNOG00000065957	0.02	0.00	blup	2197	0.01	1.2e-02	-6.1	-5.6	1.8e-08	0.34	0.57	0.03	TRUE
7	Adipose	Pdzd8	mRNA stability	ENSRNOG00000009460	0.04	0.00	blup	1998	0.01	7.6e-02	-10.5	7.4	1.4e-13	-0.50	0.42	0.04	TRUE
8	Adipose	Fam204a	mRNA stability	ENSRNOG00000009830	0.03	0.01	enet	64	0.01	5.4e-02	-5.1	6.7	2.0e-11	-0.51	0.45	0.07	FALSE
9	Adipose	Cacul1	mRNA stability	ENSRNOG00000009954	0.09	0.03	enet	62	0.04	5.6e-05	-3.1	7.6	2.7e-14	-0.74	0.96	0.04	FALSE
10	BLA	Rab11fip2	gene expression	ENSRNOG00000009523	0.11	0.05	top1	1	0.05	1.1e-03	-8.1	-8.1	4.9e-16	0.71	0.12	0.04	FALSE
11	BLA	Cacul1	gene expression	ENSRNOG00000009954	0.23	0.16	top1	1	0.16	9.5e-09	-6.1	6.1	1.4e-09	-0.43	0.94	0.00	FALSE
12	BLA	Ces2c	gene expression	ENSRNOG00000036571	0.26	0.19	lasso	16	0.20	1.1e-10	-9.0	9.0	3.2e-19	-0.71	0.93	0.07	FALSE
13	BLA	Sfxn4	gene expression	ENSRNOG00000036572	0.07	0.02	top1	1	0.02	2.1e-02	-11.4	11.4	4.4e-30	-0.83	0.06	0.04	FALSE
14	BLA	NA	gene expression	ENSRNOG00000065260	0.36	0.23	top1	1	0.23	1.9e-12	-6.1	-6.1	1.4e-09	0.22	1.00	0.00	TRUE
15	BLA	Cacul1	isoform ratio	ENSRNOT00000084760	0.07	0.00	top1	1	0.00	2.4e-01	-9.8	-9.8	8.2e-23	0.69	0.07	0.04	FALSE
16	Brain	Rab11fip2	gene expression	ENSRNOG00000009523	0.09	0.05	lasso	2	0.06	3.6e-06	-8.7	-8.4	6.5e-17	-0.46	0.96	0.04	FALSE
17	Brain	Fam204a	gene expression	ENSRNOG00000009830	0.19	0.17	top1	1	0.17	1.3e-15	-5.2	5.2	2.0e-07	-0.69	1.00	0.00	FALSE
18	Brain	Prlhr	gene expression	ENSRNOG00000009922	0.03	0.01	blup	1906	0.01	1.4e-02	-5.5	8.5	1.9e-17	-0.77	0.44	0.25	FALSE
19	Brain	Cacul1	gene expression	ENSRNOG00000009954	0.16	0.15	blup	1783	0.15	4.8e-14	-6.4	7.4	1.4e-13	-0.69	1.00	0.00	FALSE
20	Brain	Nanos1	gene expression	ENSRNOG00000025060	0.03	0.01	enet	58	0.01	2.2e-02	-9.0	-10.1	9.1e-24	0.86	0.55	0.29	FALSE
21	Brain	Ces2c	gene expression	ENSRNOG00000036571	0.20	0.28	blup	597	0.29	3.4e-27	-9.0	8.8	9.0e-19	-0.70	1.00	0.00	FALSE
22	Brain	Sfxn4	gene expression	ENSRNOG00000036572	0.09	0.08	lasso	36	0.09	2.2e-08	-5.1	7.4	1.0e-13	-0.57	1.00	0.00	FALSE
23	Brain	NA	gene expression	ENSRNOG00000065260	0.37	0.39	top1	1	0.39	3.9e-38	-6.2	-6.2	4.2e-10	0.53	1.00	0.00	FALSE
24	Brain	Cacul1	isoform ratio	ENSRNOT00000050617	0.14	0.11	top1	1	0.11	3.3e-10	-11.5	11.5	1.4e-30	-0.95	0.52	0.48	FALSE
25	Brain	Cacul1	isoform ratio	ENSRNOT00000084760	0.12	0.10	enet	5	0.11	5.6e-10	-11.5	-10.0	2.2e-23	-0.47	0.12	0.88	FALSE
26	Brain	Zfp950	isoform ratio	ENSRNOT00000047883	0.04	0.03	blup	954	0.05	9.3e-06	-9.4	8.1	8.3e-16	-0.62	0.98	0.02	TRUE
27	Brain	Cacul1	intron excision ratio	chr1:259677583:259686255	0.12	0.08	enet	36	0.10	1.6e-09	-11.0	10.6	3.9e-26	-0.25	0.15	0.85	FALSE
28	Brain	NA	intron excision ratio	chr1:258565051:258626309	0.03	0.05	top1	1	0.05	1.1e-05	6.8	-6.8	1.4e-11	0.42	0.18	0.03	FALSE
29	Brain	Cacul1	mRNA stability	ENSRNOG00000009954	0.03	0.01	top1	1	0.01	2.3e-02	-6.2	6.2	5.2e-10	-0.66	0.07	0.03	FALSE
30	Eye	NA	gene expression	ENSRNOG00000065260	0.45	0.18	top1	1	0.18	9.5e-04	-10.3	-10.3	6.3e-25	0.91	0.10	0.06	FALSE
31	IL	Ces2c	gene expression	ENSRNOG00000036571	0.35	0.35	top1	1	0.35	2.3e-09	-9.0	9.0	2.5e-19	-0.72	0.50	0.03	FALSE
32	IL	Sfxn4	gene expression	ENSRNOG00000036572	0.19	0.13	top1	1	0.13	5.3e-04	-9.1	9.1	1.3e-19	-0.79	0.08	0.05	FALSE
33	IL	NA	gene expression	ENSRNOG00000065260	0.38	0.26	top1	1	0.26	4.6e-07	-6.3	-6.3	2.7e-10	0.76	0.25	0.04	FALSE
34	LHb	Ces2c	gene expression	ENSRNOG00000036571	0.25	0.12	blup	594	0.19	2.3e-05	-9.1	8.4	6.8e-17	-0.66	0.58	0.31	FALSE
35	Liver	Rab11fip2	gene expression	ENSRNOG00000009523	0.03	0.00	blup	2371	0.01	1.3e-02	-4.8	-9.0	1.6e-19	0.80	0.37	0.29	FALSE
36	Liver	Cacul1	gene expression	ENSRNOG00000009954	0.23	0.16	lasso	15	0.16	1.3e-17	-6.1	6.1	1.3e-09	-0.58	1.00	0.00	FALSE
37	Liver	Nanos1	gene expression	ENSRNOG00000025060	0.03	0.02	top1	1	0.02	1.2e-03	-7.1	-7.1	1.8e-12	0.70	0.07	0.03	FALSE
38	Liver	Zfp950	gene expression	ENSRNOG00000032668	0.03	0.01	top1	1	0.01	7.7e-03	-10.3	-10.3	4.8e-25	0.75	0.03	0.03	FALSE
39	Liver	NA	gene expression	ENSRNOG00000065260	0.29	0.23	lasso	21	0.23	1.1e-25	-6.1	-6.0	1.9e-09	0.57	1.00	0.00	FALSE
40	Liver	Cacul1	isoform ratio	ENSRNOT00000050617	0.03	0.02	top1	1	0.02	1.3e-03	-11.3	11.3	9.3e-30	-0.94	0.07	0.03	FALSE
41	Liver	Cacul1	isoform ratio	ENSRNOT00000084760	0.03	0.01	blup	1780	0.02	4.5e-03	-11.4	-10.0	1.0e-23	0.83	0.30	0.45	FALSE
42	Liver	Cacul1	mRNA stability	ENSRNOG00000009954	0.03	0.01	top1	1	0.01	1.4e-02	-11.8	11.8	5.4e-32	-0.94	0.05	0.09	TRUE
43	NAcc	Shtn1	alternative TSS	ENSRNOT00000104427	0.11	0.07	enet	156	0.09	6.2e-07	-1.5	-5.7	1.1e-08	0.56	0.99	0.00	FALSE
44	NAcc	Prlhr	gene expression	ENSRNOG00000009922	0.14	0.09	blup	1904	0.11	2.3e-08	-11.8	10.6	2.1e-26	-0.94	0.15	0.85	FALSE
45	NAcc	Cacul1	gene expression	ENSRNOG00000009954	0.11	0.05	top1	1	0.05	7.3e-05	-6.4	6.4	2.0e-10	-0.78	0.16	0.03	FALSE
46	NAcc	Zfp950	gene expression	ENSRNOG00000032668	0.05	0.01	lasso	15	0.02	7.3e-03	-7.5	8.7	2.4e-18	-0.79	0.39	0.32	FALSE
47	NAcc	Ces2c	gene expression	ENSRNOG00000036571	0.22	0.17	blup	597	0.22	5.3e-16	-9.0	8.2	2.1e-16	-0.65	1.00	0.00	FALSE
48	NAcc	Sfxn4	gene expression	ENSRNOG00000036572	0.07	0.04	top1	1	0.04	3.8e-04	-10.3	10.3	6.7e-25	-0.86	0.06	0.03	FALSE
49	NAcc	NA	gene expression	ENSRNOG00000065260	0.36	0.29	lasso	30	0.30	5.7e-23	-6.4	-6.1	1.1e-09	-0.56	1.00	0.00	TRUE
50	NAcc	Cacul1	isoform ratio	ENSRNOT00000050617	0.05	0.05	blup	1781	0.05	9.6e-05	-11.4	11.2	3.9e-29	-0.94	0.35	0.60	FALSE
51	NAcc	Cacul1	isoform ratio	ENSRNOT00000084760	0.05	0.05	blup	1781	0.05	1.6e-04	-11.1	-11.2	3.5e-29	0.94	0.36	0.59	FALSE
52	OFC	Rab11fip2	gene expression	ENSRNOG00000009523	0.30	0.23	lasso	17	0.27	5.1e-07	-11.7	-11.5	1.3e-30	0.98	0.36	0.64	FALSE
53	OFC	Cacul1	gene expression	ENSRNOG00000009954	0.45	0.24	blup	1782	0.41	9.5e-11	-6.0	9.0	1.9e-19	-0.80	0.41	0.59	FALSE
54	OFC	Ces2c	gene expression	ENSRNOG00000036571	0.38	0.42	top1	1	0.42	3.6e-11	-9.1	9.1	8.3e-20	-0.71	0.91	0.01	FALSE
55	OFC	Sfxn4	gene expression	ENSRNOG00000036572	0.41	0.18	enet	17	0.26	7.0e-07	-9.0	9.9	4.9e-23	-0.81	0.96	0.02	FALSE
56	OFC	NA	gene expression	ENSRNOG00000065260	0.33	0.13	enet	42	0.21	1.0e-05	-5.1	-6.0	2.2e-09	0.48	0.89	0.04	FALSE
57	OFC	Rab11fip2	mRNA stability	ENSRNOG00000009523	0.16	0.19	top1	1	0.19	2.9e-05	-11.7	-11.7	1.3e-31	0.89	0.12	0.12	FALSE
58	PL	Rab11fip2	gene expression	ENSRNOG00000009523	0.06	0.04	enet	76	0.05	1.5e-04	-11.4	-11.6	3.6e-31	0.91	0.36	0.64	FALSE
59	PL	Cacul1	gene expression	ENSRNOG00000009954	0.24	0.16	enet	45	0.18	2.4e-13	-6.4	7.8	4.7e-15	-0.77	1.00	0.00	FALSE
60	PL	Ces2c	gene expression	ENSRNOG00000036571	0.39	0.38	top1	1	0.38	3.4e-30	-9.0	9.0	3.2e-19	-0.71	1.00	0.00	FALSE
61	PL	Sfxn4	gene expression	ENSRNOG00000036572	0.17	0.05	enet	158	0.10	9.5e-08	-8.9	8.5	2.1e-17	-0.68	0.94	0.06	FALSE
62	PL	NA	gene expression	ENSRNOG00000065957	0.12	0.07	top1	1	0.07	9.6e-06	7.9	-7.9	3.7e-15	0.59	0.49	0.02	FALSE
63	PL	NA	gene expression	ENSRNOG00000068145	0.06	0.03	lasso	13	0.04	6.9e-04	7.7	-9.1	1.0e-19	0.76	0.46	0.41	TRUE
64	PL	Cacul1	isoform ratio	ENSRNOT00000050617	0.03	0.02	top1	1	0.02	1.8e-02	-11.1	11.1	1.7e-28	-0.90	0.06	0.03	FALSE
65	PL	Zfp950	intron excision ratio	chr1:260237329:260247276	0.03	0.01	blup	954	0.02	1.2e-02	-11.0	9.6	6.0e-22	-0.78	0.26	0.46	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.