Hub : Traits : Extensor digitorum longus weight : ← : →

chr2:90,475,129-95,023,945

Trait: Extensor digitorum longus weight

Best TWAS P=7.20e-14 · Best GWAS P=1.02e-13 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Snx16	alternative TSS	XM_039103035.1	0.03	1	0.01	7.5e-03	-6.93	4.23e-12	0.04	FALSE
Adipose	Fabp12	gene expression	Fabp12	0.09	1	0.06	1.2e-07	6.4	1.57e-10	0.06	FALSE
Adipose	Hey1	gene expression	Hey1	0.04	1	0	1.1e-01	7.32	2.49e-13	0.03	FALSE
Adipose	LOC102553210	gene expression	LOC102553210	0.07	2122	0.03	2.5e-04	6.45	1.12e-10	0.58	FALSE
Adipose	LOC120100773	gene expression	LOC120100773	0.08	1	0.01	8.8e-03	5.54	2.96e-08	0.03	FALSE
Adipose	Snx16	isoform ratio	XM_006232135.4	0.03	2048	0.02	3.9e-03	-5.86	4.72e-09	0.28	FALSE
Adipose	Snx16	intron excision ratio	chr2_91354845_91356529	0.04	2048	0.02	2.2e-03	-5.95	2.67e-09	0.42	FALSE
Adipose	Fabp4	mRNA stability	Fabp4	0.08	1	0.05	1.9e-06	-6.92	4.51e-12	0.66	FALSE
Adipose	Impa1	mRNA stability	Impa1	0.36	162	0.14	8.2e-16	-5.19	2.08e-07	0.01	FALSE
Adipose	LOC103691511	mRNA stability	LOC103691511	0.13	2068	0.06	1.0e-06	-5.88	4.10e-09	0.26	FALSE
Adipose	LOC120093158	mRNA stability	LOC120093158	0.19	1916	0.12	5.0e-13	6.27	3.65e-10	0.49	FALSE
Adipose	Tpd52	mRNA stability	Tpd52	0.04	2108	0.01	2.3e-02	-6.06	1.32e-09	0.31	TRUE
BLA	Fabp4	gene expression	Fabp4	0.43	28	0.25	1.9e-13	6.46	1.07e-10	0.43	FALSE
BLA	Fabp5	gene expression	Fabp5	0.21	1	0.12	3.9e-07	-6.65	2.90e-11	0.15	FALSE
BLA	Hey1	gene expression	Hey1	0.08	2629	0.03	1.4e-02	7.15	8.67e-13	0.4	FALSE
BLA	Pag1	gene expression	Pag1	0.12	1	0.04	2.8e-03	6.42	1.37e-10	0.04	FALSE
BLA	Pmp2	gene expression	Pmp2	0.1	1	0.04	2.6e-03	-6.92	4.65e-12	0.05	FALSE
BLA	Tpd52	gene expression	Tpd52	0.24	1	0.13	1.5e-07	5.57	2.50e-08	0	TRUE
BLA	Tpd52	mRNA stability	Tpd52	0.1	2109	0.02	2.6e-02	-5.5	3.80e-08	0.12	FALSE
Brain	Zfp704	alternative TSS	XM_039103595.1	0.03	2	0.01	5.0e-02	6.88	5.88e-12	0.2	FALSE
Brain	Fabp4	gene expression	Fabp4	0.19	1917	0.08	1.5e-07	6.75	1.45e-11	0.56	FALSE
Brain	Fabp5	gene expression	Fabp5	0.22	2075	0.11	2.2e-10	6.65	2.96e-11	0.74	FALSE
Brain	LOC120093158	gene expression	LOC120093158	0.1	2	0.03	9.4e-04	6.34	2.25e-10	0.48	FALSE
Brain	Zbtb10	gene expression	Zbtb10	0.16	1	0.08	4.5e-08	-7.39	1.46e-13	0.72	FALSE
Brain	Snx16	isoform ratio	NM_022289.3	0.05	2050	0.02	9.2e-03	6.59	4.35e-11	0.43	FALSE
Brain	Snx16	isoform ratio	XM_006232135.4	0.09	2050	0.05	8.9e-06	-5.65	1.61e-08	0.46	FALSE
Brain	Zfp704	isoform ratio	XM_039103595.1	0.05	11	0.02	4.5e-03	7.23	4.70e-13	0.26	FALSE
Brain	Snx16	intron excision ratio	chr2_91354845_91356529	0.13	2050	0.06	1.8e-06	-6.21	5.20e-10	0.59	FALSE
Brain	Snx16	intron excision ratio	chr2_91355443_91356529	0.04	2050	0.01	4.1e-02	6.04	1.53e-09	0.26	FALSE
Brain	Tpd52	intron excision ratio	chr2_92804650_92812941	0.04	2	0.03	1.4e-03	-6.55	5.71e-11	0.25	FALSE
Brain	Tpd52	intron excision ratio	chr2_92805700_92811676	0.05	2109	0.02	4.0e-03	-7.25	4.06e-13	0.47	FALSE
Brain	Impa1	mRNA stability	Impa1	0.31	1989	0.11	1.4e-10	6.17	6.86e-10	0.44	TRUE
Brain	Mrps28	mRNA stability	Mrps28	0.08	2056	0.02	4.8e-03	6.94	3.97e-12	0.44	FALSE
Brain	Tpd52	mRNA stability	Tpd52	0.36	2109	0.2	3.2e-18	-6.9	5.16e-12	0.38	FALSE
Eye	LOC108349981	gene expression	LOC108349981	0.76	1	0.38	5.8e-07	-5.25	1.54e-07	0.05	FALSE
Eye	Tpd52	intron excision ratio	chr2_92804650_92811676	0.38	4	0.2	6.1e-04	5.57	2.52e-08	0.2	FALSE
Eye	Tpd52	intron excision ratio	chr2_92804650_92812941	0.29	1	0.08	2.7e-02	7.32	2.49e-13	0.06	FALSE
Eye	Mrps28	mRNA stability	Mrps28	0.34	2	0.24	1.2e-04	5.21	1.89e-07	0.18	TRUE
Eye	Tpd52	mRNA stability	Tpd52	0.69	1	0.29	2.0e-05	5.38	7.37e-08	0.06	FALSE
IL	Impa1	alternative TSS	NM_032057.2	0.29	46	0.07	1.1e-02	-5.97	2.39e-09	0.35	FALSE
IL	Impa1	alternative TSS	XM_006232151.4	0.26	1	0.09	3.6e-03	6.47	9.52e-11	0.05	FALSE
IL	Fabp4	gene expression	Fabp4	0.75	4	0.12	7.0e-04	6.9	5.33e-12	0.6	FALSE
IL	Fabp5	gene expression	Fabp5	0.27	2075	0.09	4.0e-03	6.55	5.74e-11	0.28	FALSE
IL	Zfp704	gene expression	Zfp704	0.26	2018	0.07	9.3e-03	-5.93	2.98e-09	0.21	FALSE
IL	Tpd52	isoform ratio	NM_001106421.2	0.29	1	0.08	6.1e-03	5.19	2.14e-07	0.05	FALSE
IL	Tpd52	mRNA stability	Tpd52	0.59	1	0.27	3.5e-07	7.06	1.72e-12	0.08	FALSE
LHb	Fabp5	gene expression	Fabp5	0.4	97	0.1	2.8e-03	-5.32	1.02e-07	0.09	FALSE
LHb	Pag1	gene expression	Pag1	0.26	1	0.03	6.8e-02	6.46	1.04e-10	0.05	FALSE
LHb	Tpd52	gene expression	Tpd52	0.35	1	0.17	7.1e-05	7.32	2.55e-13	0.06	FALSE
LHb	Impa1	mRNA stability	Impa1	0.41	1	0.06	1.9e-02	-6.89	5.70e-12	0.05	FALSE
LHb	Tpd52	mRNA stability	Tpd52	0.47	5	0.2	1.6e-05	7.34	2.14e-13	0.5	FALSE
Liver	Fabp12	gene expression	Fabp12	0.97	13	0.46	1.6e-57	-5.84	5.29e-09	0	FALSE
Liver	Fabp5	gene expression	Fabp5	0.05	2074	0.02	2.0e-03	5.39	6.88e-08	0.33	TRUE
Liver	Zbtb10	gene expression	Zbtb10	0.04	2325	0.02	4.1e-03	6.72	1.80e-11	0.45	FALSE
Liver	Fabp12	intron excision ratio	chr2_91503212_91511657	0.66	25	0.46	1.5e-56	5.31	1.10e-07	0	FALSE
Liver	Fabp12	intron excision ratio	chr2_91551040_91553236	0.5	418	0.35	5.7e-40	5.92	3.25e-09	0	FALSE
Liver	LOC120093158	intron excision ratio	chr2_91503212_91511657	0.66	26	0.46	1.5e-56	5.3	1.18e-07	0	FALSE
Liver	LOC120093158	intron excision ratio	chr2_91551040_91553236	0.5	501	0.35	5.8e-40	5.92	3.16e-09	0	FALSE
Liver	Chmp4c	mRNA stability	Chmp4c	0.03	2003	0.01	7.5e-03	-5.47	4.41e-08	0.27	FALSE
Liver	Pag1	mRNA stability	Pag1	0.03	2134	0.01	1.1e-02	-5.88	4.18e-09	0.14	FALSE
Liver	Tpd52	mRNA stability	Tpd52	0.13	1	0.07	3.9e-08	7.13	1.02e-12	0.28	FALSE
NAcc	Fabp4	gene expression	Fabp4	0.12	1	0.1	3.6e-11	-6.92	4.62e-12	0.69	FALSE
NAcc	LOC120093158	gene expression	LOC120093158	0.02	1917	0.01	5.5e-02	-6.3	2.89e-10	0.26	FALSE
NAcc	Pag1	gene expression	Pag1	0.17	2135	0.11	9.7e-13	-6.82	8.86e-12	0.29	FALSE
NAcc	Pmp2	gene expression	Pmp2	0.09	1914	0.06	5.6e-08	6.33	2.50e-10	0.5	FALSE
NAcc	Zbtb10	gene expression	Zbtb10	0.1	1	0.07	3.4e-08	-7.23	4.89e-13	0.46	FALSE
NAcc	Snx16	isoform ratio	XM_006232135.4	0.04	2050	0.02	2.6e-03	-6.27	3.54e-10	0.43	FALSE
NAcc	Snx16	intron excision ratio	chr2_91354845_91356529	0.06	1	0.02	1.6e-03	6.29	3.10e-10	0.03	FALSE
NAcc	Impa1	mRNA stability	Impa1	0.15	3	0.07	8.6e-09	5.26	1.46e-07	0.03	FALSE
NAcc	Tpd52	mRNA stability	Tpd52	0.25	2109	0.19	8.4e-22	-6.93	4.23e-12	0.57	FALSE
NAcc	Zc2hc1a	mRNA stability	Zc2hc1a	0.03	2443	0.01	3.2e-02	5.32	1.06e-07	0.47	FALSE
OFC	Fabp4	gene expression	Fabp4	0.36	1917	0.09	3.6e-03	6.78	1.22e-11	0.47	FALSE
OFC	Fabp5	gene expression	Fabp5	0.38	2075	0.13	5.4e-04	6.73	1.74e-11	0.55	FALSE
OFC	Mrps28	gene expression	Mrps28	0.37	53	0.17	6.5e-05	-7.48	7.20e-14	0.62	TRUE
OFC	Zbtb10	gene expression	Zbtb10	0.27	1	0.13	5.8e-04	-7.22	5.02e-13	0.06	FALSE
OFC	Tpd52	intron excision ratio	chr2_92804650_92805674	0.19	1	0.13	4.5e-04	7.36	1.86e-13	0.06	FALSE
OFC	Tpd52	mRNA stability	Tpd52	0.32	39	0.1	2.0e-03	7.37	1.71e-13	0.42	FALSE
PL	Tpd52	alternative TSS	NM_001401807.1	0.04	1	0.02	2.2e-03	7.13	1.03e-12	0.03	FALSE
PL	Fabp4	gene expression	Fabp4	0.43	1	0.33	9.4e-37	-6.96	3.40e-12	0.75	FALSE
PL	Fabp5	gene expression	Fabp5	0.35	2075	0.3	5.7e-33	6.57	5.03e-11	0.34	FALSE
PL	Hey1	gene expression	Hey1	0.22	17	0.09	2.1e-10	-7.37	1.66e-13	0.65	FALSE
PL	LOC102553210	gene expression	LOC102553210	0.05	2125	0.02	2.0e-03	-5.65	1.62e-08	0.2	FALSE
PL	Mrps28	gene expression	Mrps28	0.11	1	0.05	3.3e-06	-7	2.56e-12	0.11	FALSE
PL	Pmp2	gene expression	Pmp2	0.1	1	0.06	2.8e-07	-6.65	2.90e-11	0.26	FALSE
PL	Zbtb10	gene expression	Zbtb10	0.09	1	0.03	1.2e-04	-7.32	2.55e-13	0.36	FALSE
PL	Snx16	isoform ratio	XM_006232135.4	0.03	3	0.01	2.8e-02	6.39	1.67e-10	0.41	FALSE
PL	Snx16	intron excision ratio	chr2_91354845_91356529	0.13	1	0.08	3.1e-09	6.92	4.52e-12	0.65	FALSE
PL	Tpd52	mRNA stability	Tpd52	0.33	10	0.23	8.8e-25	-7.14	9.19e-13	0.39	FALSE
pVTA	Fabp4	gene expression	Fabp4	0.17	23	0.18	2.2e-08	7.03	2.04e-12	0.5	FALSE
pVTA	LOC102553210	gene expression	LOC102553210	0.06	2125	0.03	1.8e-02	-6.14	8.20e-10	0.27	FALSE
pVTA	LOC108349981	gene expression	LOC108349981	0.09	1	0.04	1.0e-02	-5.24	1.60e-07	0.04	FALSE
pVTA	LOC120093158	gene expression	LOC120093158	0.06	11	0.05	2.8e-03	-6.27	3.59e-10	0.3	FALSE
pVTA	Snx16	intron excision ratio	chr2_91354845_91356529	0.14	1	0.13	2.0e-06	7.07	1.59e-12	0.6	FALSE
pVTA	Tpd52	mRNA stability	Tpd52	0.09	2109	0.06	1.1e-03	-6.5	7.79e-11	0.24	FALSE
RMTg	Tpd52	gene expression	Tpd52	0.24	47	0.13	2.3e-04	-6.59	4.41e-11	0.48	FALSE