Best TWAS P=8.412962e-08 · Best GWAS P=2.474872e-08 conditioned to 1
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Ythdf3 | alternative polyA | ENSRNOT00000095002 | 0.05 | 0.01 | top1 | 1 | 0.01 | 0.0082 | -5.3 | -5.3 | 1.3e-07 | 0.95 | 0.07 | 0.03 | FALSE |
| 2 | Adipose | Ythdf3 | alternative polyA | ENSRNOT00000095002 | 0.05 | 0.01 | top1 | 1 | 0.01 | 0.0085 | -5.3 | -5.3 | 1.3e-07 | 0.95 | 0.07 | 0.03 | FALSE |
| 3 | Liver | Hnf4g | intron excision ratio | chr2:97888353:97891069 | 0.04 | 0.01 | top1 | 1 | 0.01 | 0.0120 | -5.4 | -5.4 | 8.4e-08 | 0.94 | 0.05 | 0.03 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.