Best TWAS P=3.24e-10 · Best GWAS P=1.59e-10 conditioned to 1.00e+00
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Brain | Ralyl | intron excision ratio | chr2:87631467:87663759 | 0.06 | 1 | 0.02 | 3.7e-03 | -5.64 | 1.69e-08 | 0.03 | FALSE |
| LHb | Ralyl | alternative TSS | ENSRNOT00000015195 | 0.6 | 18 | 0.22 | 5.1e-06 | 6.29 | 3.24e-10 | 0.8 | TRUE |
| LHb | Ralyl | alternative TSS | ENSRNOT00000100768 | 0.6 | 5 | 0.27 | 4.0e-07 | -6.11 | 1.01e-09 | 0.65 | FALSE |
| LHb | Ralyl | alternative TSS | ENSRNOT00000015195 | 0.58 | 17 | 0.2 | 1.7e-05 | 6.2 | 5.68e-10 | 0.77 | FALSE |
| LHb | Ralyl | alternative TSS | ENSRNOT00000100768 | 0.52 | 6 | 0.22 | 6.6e-06 | -6.18 | 6.26e-10 | 0.67 | FALSE |
| LHb | Ralyl | gene expression | ENSRNOG00000011400 | 0.73 | 1 | 0.13 | 6.6e-04 | 5.35 | 8.72e-08 | 0.05 | FALSE |
| LHb | Ralyl | mRNA stability | ENSRNOG00000011400 | 0.41 | 6 | 0.15 | 2.2e-04 | 5.9 | 3.67e-09 | 0.53 | FALSE |
| NAcc | Ralyl | alternative polyA | ENSRNOT00000015195 | 0.09 | 108 | 0.02 | 2.1e-02 | 5.23 | 1.68e-07 | 0.49 | FALSE |
| OFC | Ralyl | alternative TSS | ENSRNOT00000100768 | 0.33 | 5 | 0.11 | 1.2e-03 | -5.73 | 1.03e-08 | 0.27 | FALSE |
| OFC | Ralyl | intron excision ratio | chr2:87663834:87750876 | 0.24 | 1 | 0.06 | 1.3e-02 | 5.61 | 2.00e-08 | 0.05 | FALSE |
| PL | Lrrcc1 | intron excision ratio | chr2:87058023:87060061 | 0.07 | 1 | 0.03 | 2.0e-03 | -5.36 | 8.35e-08 | 0.04 | FALSE |