Hub : Traits : EDL weight in grams : ← →

chr2:89,673,058-95,023,945

Best TWAS P=1.827976e-13 · Best GWAS P=1.024767e-13 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Tpd52	alternative polyA	ENSRNOT00000120271	0.05	0.02	top1	1	0.02	3.4e-03	7.3	7.3	2.5e-13	0.97	0.07	0.04	FALSE
2	Adipose	Tpd52	alternative polyA	ENSRNOT00000099506	0.05	0.02	top1	1	0.02	3.7e-03	7.3	-7.3	2.5e-13	-0.98	0.06	0.04	FALSE
3	Adipose	Tpd52	alternative polyA	ENSRNOT00000120271	0.05	0.02	top1	1	0.02	3.8e-03	7.3	7.3	2.5e-13	0.98	0.06	0.04	FALSE
4	Adipose	Tpd52	alternative TSS	ENSRNOT00000120271	0.04	0.01	top1	1	0.01	1.0e-02	7.0	-7.0	3.3e-12	-1.00	0.06	0.03	FALSE
5	Adipose	Zbtb10	alternative TSS	ENSRNOT00000081553	0.29	0.17	lasso	27	0.19	2.7e-20	7.1	-7.0	2.2e-12	-0.94	0.46	0.54	FALSE
6	Adipose	Zbtb10	alternative TSS	ENSRNOT00000087598	0.28	0.17	lasso	16	0.19	2.6e-20	7.1	7.0	2.8e-12	0.94	0.46	0.54	FALSE
7	Adipose	Snx16	gene expression	ENSRNOG00000009953	0.11	0.04	enet	157	0.06	1.2e-07	-4.4	-5.7	9.2e-09	-0.37	1.00	0.00	FALSE
8	Adipose	Fabp12	gene expression	ENSRNOG00000038825	0.14	0.08	top1	1	0.08	3.2e-09	7.0	-7.0	2.6e-12	-0.82	0.23	0.77	FALSE
9	Adipose	Hey1	gene expression	ENSRNOG00000062882	0.04	0.00	blup	2629	0.02	5.5e-03	-5.5	-6.7	1.7e-11	-0.90	0.50	0.28	FALSE
10	Adipose	Snx16	isoform ratio	ENSRNOT00000083909	0.03	0.01	top1	1	0.01	2.5e-02	6.9	6.9	5.4e-12	0.84	0.06	0.03	FALSE
11	Adipose	Tpd52	isoform ratio	ENSRNOT00000120271	0.05	0.02	top1	1	0.02	1.5e-03	-5.2	5.2	1.5e-07	0.85	0.06	0.03	FALSE
12	Adipose	Zbtb10	isoform ratio	ENSRNOT00000081553	0.25	0.15	lasso	5	0.16	4.9e-17	7.1	-7.0	2.1e-12	-0.93	0.47	0.53	FALSE
13	Adipose	Zbtb10	isoform ratio	ENSRNOT00000087598	0.23	0.14	blup	2314	0.15	1.4e-16	7.1	7.2	4.8e-13	0.97	0.46	0.54	FALSE
14	Adipose	Fabp4	mRNA stability	ENSRNOG00000010805	0.05	0.03	top1	1	0.03	3.2e-04	6.9	6.9	5.4e-12	0.84	0.09	0.09	FALSE
15	BLA	Fabp4	gene expression	ENSRNOG00000010805	0.41	0.21	lasso	10	0.24	2.8e-13	6.4	6.4	1.5e-10	0.84	0.53	0.47	FALSE
16	BLA	Pmp2	gene expression	ENSRNOG00000022707	0.10	0.08	lasso	1	0.08	5.9e-05	6.4	6.4	1.2e-10	0.81	0.46	0.47	FALSE
17	BLA	NA	gene expression	ENSRNOG00000049075	0.20	0.06	blup	2083	0.08	3.5e-05	6.5	6.5	7.6e-11	0.83	0.67	0.33	FALSE
18	BLA	Zfp704	gene expression	ENSRNOG00000054426	0.08	0.01	blup	2020	0.03	7.8e-03	6.4	-5.9	3.6e-09	-0.79	0.36	0.14	FALSE
19	BLA	Pag1	gene expression	ENSRNOG00000061328	0.06	0.01	top1	1	0.01	1.2e-01	6.4	-6.4	1.1e-10	-0.88	0.08	0.04	FALSE
20	BLA	Hey1	gene expression	ENSRNOG00000062882	0.07	0.03	top1	1	0.03	1.5e-02	7.3	7.3	2.6e-13	0.98	0.10	0.04	FALSE
21	BLA	NA	gene expression	ENSRNOG00000066286	0.06	0.02	lasso	20	0.02	2.0e-02	6.7	-6.6	3.7e-11	-0.84	0.44	0.12	FALSE
22	BLA	Slc10a5	gene expression	ENSRNOG00000067758	0.16	0.08	top1	1	0.08	5.3e-05	7.0	-7.0	3.3e-12	-0.84	0.11	0.14	FALSE
23	BLA	Snx16	isoform ratio	ENSRNOT00000050987	0.09	0.03	blup	2053	0.04	2.6e-03	-4.6	-6.1	1.3e-09	-0.74	0.48	0.33	FALSE
24	BLA	Snx16	isoform ratio	ENSRNOT00000096600	0.10	0.04	top1	1	0.04	2.8e-03	6.6	6.6	4.3e-11	0.84	0.08	0.04	FALSE
25	BLA	Tpd52	isoform ratio	ENSRNOT00000099506	0.08	0.05	top1	1	0.05	1.8e-03	-5.5	-5.5	3.5e-08	-0.71	0.08	0.04	FALSE
26	BLA	Tpd52	isoform ratio	ENSRNOT00000117383	0.06	0.04	top1	1	0.04	4.3e-03	-5.5	5.5	3.5e-08	0.79	0.08	0.04	FALSE
27	BLA	Zfp704	mRNA stability	ENSRNOG00000054426	0.08	0.00	blup	2020	0.03	1.3e-02	6.5	-6.1	8.6e-10	-0.82	0.45	0.16	FALSE
28	Brain	Tpd52	alternative polyA	ENSRNOT00000099506	0.12	0.05	top1	1	0.05	2.0e-05	-5.5	-5.5	3.6e-08	-0.77	0.19	0.03	FALSE
29	Brain	Tpd52	alternative polyA	ENSRNOT00000117383	0.05	0.02	top1	1	0.02	6.6e-03	-5.5	5.5	3.6e-08	0.83	0.07	0.03	FALSE
30	Brain	Fabp4	gene expression	ENSRNOG00000010805	0.18	0.10	top1	1	0.10	6.0e-10	6.4	6.4	1.2e-10	0.83	0.91	0.09	FALSE
31	Brain	NA	gene expression	ENSRNOG00000049075	0.23	0.15	top1	1	0.15	6.3e-14	7.2	7.2	7.3e-13	0.88	0.12	0.88	FALSE
32	Brain	Zfp704	gene expression	ENSRNOG00000054426	0.03	0.01	top1	1	0.01	2.3e-02	7.4	-7.4	1.8e-13	-0.93	0.06	0.04	TRUE
33	Brain	NA	gene expression	ENSRNOG00000066793	0.04	0.01	top1	1	0.01	1.5e-02	6.3	-6.3	3.2e-10	-0.88	0.07	0.03	FALSE
34	Brain	Slc10a5	gene expression	ENSRNOG00000067758	0.24	0.11	blup	1993	0.18	2.7e-16	-2.6	-5.1	2.7e-07	-0.64	0.95	0.05	FALSE
35	Brain	Snx16	isoform ratio	ENSRNOT00000083909	0.09	0.05	top1	1	0.05	1.7e-05	6.3	6.3	3.2e-10	0.83	0.28	0.03	FALSE
36	Brain	Tpd52	isoform ratio	ENSRNOT00000099506	0.11	0.04	top1	1	0.04	1.8e-04	-5.5	-5.5	3.6e-08	-0.75	0.18	0.03	FALSE
37	Brain	Tpd52	isoform ratio	ENSRNOT00000117383	0.03	0.00	enet	45	0.00	1.6e-01	-5.3	6.7	2.3e-11	0.90	0.34	0.24	FALSE
38	Brain	Snx16	intron excision ratio	chr2:91354845:91356529	0.14	0.08	top1	1	0.08	1.3e-07	6.6	-6.6	3.4e-11	-0.83	0.79	0.21	FALSE
39	Brain	Tpd52	intron excision ratio	chr2:92804650:92812941	0.04	0.00	blup	2108	0.01	1.9e-02	-2.3	5.5	4.2e-08	0.80	0.38	0.28	FALSE
40	Brain	Tpd52	intron excision ratio	chr2:92805700:92811676	0.04	0.01	top1	1	0.01	1.5e-02	7.4	-7.4	1.9e-13	-0.98	0.07	0.04	FALSE
41	Brain	Zbtb10	intron excision ratio	chr2:92498889:92508405	0.03	0.00	top1	1	0.00	4.5e-01	7.1	-7.1	1.3e-12	-0.91	0.07	0.03	FALSE
42	Brain	Tpd52	mRNA stability	ENSRNOG00000011441	0.23	0.11	top1	1	0.11	2.2e-10	-5.5	-5.5	2.9e-08	-0.79	1.00	0.00	FALSE
43	Brain	Mrps28	mRNA stability	ENSRNOG00000032630	0.08	0.01	blup	2057	0.03	1.8e-03	7.2	6.8	1.0e-11	0.91	0.64	0.34	FALSE
44	Brain	Zfp704	mRNA stability	ENSRNOG00000054426	0.07	0.05	top1	1	0.05	2.6e-05	7.1	-7.1	1.2e-12	-0.92	0.20	0.17	FALSE
45	Eye	Fabp12	intron excision ratio	chr2:91551040:91553236	0.43	0.17	blup	1926	0.26	6.9e-05	-5.0	-5.8	8.3e-09	-0.74	0.57	0.33	FALSE
46	Eye	Tpd52	mRNA stability	ENSRNOG00000011441	0.31	0.20	lasso	16	0.21	3.5e-04	-5.5	-5.5	3.5e-08	-0.74	0.65	0.19	FALSE
47	IL	Zc2hc1a	alternative polyA	ENSRNOT00000095126	0.29	0.01	blup	2421	0.01	1.9e-01	6.5	-5.8	8.3e-09	-0.67	0.24	0.25	FALSE
48	IL	Zc2hc1a	alternative polyA	ENSRNOT00000095126	0.34	0.01	blup	2421	0.02	9.7e-02	6.5	-5.4	5.6e-08	-0.66	0.26	0.29	FALSE
49	IL	Zc2hc1a	alternative polyA	ENSRNOT00000109624	0.30	-0.01	blup	2421	0.01	1.9e-01	6.5	5.4	5.7e-08	0.66	0.25	0.25	FALSE
50	IL	Fabp4	gene expression	ENSRNOG00000010805	0.76	0.17	enet	6	0.17	5.7e-05	6.9	6.9	5.9e-12	0.82	0.33	0.62	FALSE
51	IL	NA	gene expression	ENSRNOG00000049075	0.27	0.09	top1	1	0.09	4.0e-03	6.4	6.4	1.4e-10	0.87	0.11	0.05	FALSE
52	IL	Tpd52	mRNA stability	ENSRNOG00000011441	0.30	0.12	top1	1	0.12	7.2e-04	7.3	-7.3	2.4e-13	-0.97	0.11	0.06	FALSE
53	LHb	Tpd52	mRNA stability	ENSRNOG00000011441	0.27	0.08	top1	1	0.08	6.7e-03	-5.4	-5.4	5.1e-08	-0.79	0.11	0.05	FALSE
54	Liver	Snx16	alternative TSS	ENSRNOT00000083909	0.02	0.00	top1	1	0.00	1.3e-01	-5.1	-5.1	2.8e-07	-0.81	0.06	0.03	FALSE
55	Liver	Snx16	alternative TSS	ENSRNOT00000083909	0.03	0.01	top1	1	0.01	1.4e-02	-5.1	-5.1	2.8e-07	-0.79	0.06	0.03	FALSE
56	Liver	Snx16	alternative TSS	ENSRNOT00000096600	0.03	0.01	blup	2050	0.01	3.7e-02	6.4	6.2	5.5e-10	0.76	0.42	0.30	FALSE
57	Liver	Zbtb10	alternative TSS	ENSRNOT00000081553	0.11	0.04	top1	1	0.04	3.4e-05	6.4	-6.4	1.4e-10	-0.97	0.20	0.03	FALSE
58	Liver	Zbtb10	alternative TSS	ENSRNOT00000087598	0.09	0.04	top1	1	0.04	6.9e-05	6.4	6.4	1.4e-10	0.97	0.14	0.03	FALSE
59	Liver	Fabp12	gene expression	ENSRNOG00000038825	0.79	0.45	enet	231	0.47	1.0e-57	-4.9	-5.8	6.6e-09	-0.75	1.00	0.00	FALSE
60	Liver	NA	gene expression	ENSRNOG00000049075	0.04	0.01	enet	8	0.02	1.4e-03	-2.7	6.2	5.8e-10	0.83	0.46	0.34	FALSE
61	Liver	Zbtb10	isoform ratio	ENSRNOT00000081553	0.16	0.04	top1	1	0.04	3.0e-05	6.4	-6.4	1.4e-10	-0.97	0.22	0.02	FALSE
62	Liver	Zbtb10	isoform ratio	ENSRNOT00000087598	0.15	0.04	top1	1	0.04	7.8e-05	6.4	6.4	1.4e-10	0.97	0.14	0.03	FALSE
63	Liver	Fabp12	intron excision ratio	chr2:91503212:91511657	0.68	0.48	lasso	21	0.50	8.3e-63	-4.9	5.3	1.4e-07	0.63	1.00	0.00	FALSE
64	Liver	Fabp12	intron excision ratio	chr2:91551040:91553236	0.50	0.38	lasso	41	0.39	1.0e-45	-5.0	-5.7	9.8e-09	-0.68	1.00	0.00	FALSE
65	Liver	Tpd52	mRNA stability	ENSRNOG00000011441	0.07	0.04	top1	1	0.04	7.4e-05	7.3	-7.3	2.5e-13	-0.99	0.10	0.10	FALSE
66	NAcc	Tpd52	mRNA stability	ENSRNOG00000011441	0.36	0.16	top1	1	0.16	1.9e-04	-5.2	-5.2	2.4e-07	-0.78	0.12	0.05	FALSE
67	NAcc2	Fabp4	gene expression	ENSRNOG00000010805	0.11	0.05	enet	20	0.05	1.3e-03	6.4	5.7	9.0e-09	0.79	0.53	0.42	FALSE
68	NAcc2	Pmp2	gene expression	ENSRNOG00000022707	0.17	0.08	top1	1	0.08	4.8e-05	6.4	6.4	1.2e-10	0.83	0.29	0.05	FALSE
69	NAcc2	Pag1	gene expression	ENSRNOG00000061328	0.07	0.02	top1	1	0.02	3.5e-02	7.3	-7.3	2.3e-13	-0.91	0.08	0.05	FALSE
70	NAcc2	NA	gene expression	ENSRNOG00000066793	0.16	0.04	blup	2041	0.04	2.9e-03	6.3	-6.1	1.2e-09	-0.81	0.62	0.34	FALSE
71	NAcc2	Tpd52	mRNA stability	ENSRNOG00000011441	0.07	0.02	top1	1	0.02	4.0e-02	-5.3	-5.3	1.3e-07	-0.71	0.08	0.04	FALSE
72	OFC	Fabp4	gene expression	ENSRNOG00000010805	0.43	0.08	top1	1	0.08	7.4e-03	6.8	6.8	8.4e-12	0.83	0.10	0.06	FALSE
73	OFC	Tpd52	gene expression	ENSRNOG00000011441	0.39	0.13	lasso	3	0.15	2.1e-04	-5.6	-5.6	2.7e-08	-0.71	0.75	0.14	FALSE
74	OFC	Pmp2	gene expression	ENSRNOG00000022707	0.31	0.02	enet	17	0.03	7.2e-02	-2.7	6.8	8.3e-12	0.83	0.23	0.14	FALSE
75	OFC	Mrps28	gene expression	ENSRNOG00000032630	0.44	0.11	top1	1	0.11	1.5e-03	7.3	7.3	2.4e-13	1.00	0.10	0.06	FALSE
76	OFC	NA	gene expression	ENSRNOG00000049075	0.37	0.08	top1	1	0.08	6.3e-03	6.4	6.4	1.5e-10	0.88	0.11	0.05	FALSE
77	OFC	Hey1	gene expression	ENSRNOG00000062882	0.19	0.13	top1	1	0.13	6.0e-04	6.8	6.8	9.2e-12	0.96	0.14	0.05	FALSE
78	OFC	tGap1	isoform ratio	ENSRNOT00000033404	0.44	-0.01	blup	2380	0.09	4.7e-03	-2.4	5.4	8.5e-08	0.62	0.34	0.20	FALSE
79	OFC	tGap1	isoform ratio	ENSRNOT00000082912	0.48	0.03	blup	2380	0.11	1.5e-03	6.9	-5.6	2.8e-08	-0.66	0.36	0.26	FALSE
80	PL	Fabp4	gene expression	ENSRNOG00000010805	0.59	0.14	top1	1	0.14	4.1e-04	7.1	7.1	1.6e-12	0.83	0.10	0.10	FALSE
81	PL	Mrps28	gene expression	ENSRNOG00000032630	0.30	0.03	top1	1	0.03	7.0e-02	7.3	7.3	2.2e-13	0.99	0.10	0.05	FALSE
82	PL	NA	gene expression	ENSRNOG00000049075	0.51	0.08	enet	9	0.24	2.5e-06	6.5	6.4	1.2e-10	0.81	0.71	0.23	FALSE
83	PL	Zfp704	gene expression	ENSRNOG00000054426	0.35	0.01	enet	7	0.03	5.4e-02	-2.4	5.3	9.3e-08	0.82	0.27	0.04	FALSE
84	PL	Tpd52	mRNA stability	ENSRNOG00000011441	0.33	0.05	top1	1	0.05	2.5e-02	-5.4	-5.4	5.1e-08	-0.87	0.11	0.05	FALSE
85	PL2	Fabp4	gene expression	ENSRNOG00000010805	0.43	0.24	top1	1	0.24	1.8e-13	6.4	6.4	1.7e-10	0.83	0.94	0.06	FALSE
86	PL2	Pmp2	gene expression	ENSRNOG00000022707	0.18	0.10	top1	1	0.10	4.2e-06	6.5	6.5	1.1e-10	0.83	0.25	0.05	FALSE
87	PL2	Mrps28	gene expression	ENSRNOG00000032630	0.08	0.02	top1	1	0.02	2.3e-02	6.9	6.9	4.3e-12	0.99	0.08	0.04	FALSE
88	PL2	NA	gene expression	ENSRNOG00000049075	0.42	0.23	top1	1	0.23	1.4e-12	6.5	6.5	8.0e-11	0.87	0.92	0.07	FALSE
89	PL2	Hey1	gene expression	ENSRNOG00000062882	0.11	0.05	top1	1	0.05	1.1e-03	7.4	7.4	1.9e-13	0.93	0.10	0.05	FALSE
90	PL2	NA	gene expression	ENSRNOG00000066286	0.08	0.01	blup	2033	0.02	3.9e-02	-4.7	-6.5	1.1e-10	-0.85	0.48	0.25	FALSE
91	PL2	Tpd52	isoform ratio	ENSRNOT00000077270	0.08	0.02	top1	1	0.02	2.4e-02	-5.3	5.3	1.0e-07	0.92	0.08	0.04	FALSE
92	PL2	tGap1	isoform ratio	ENSRNOT00000082912	0.09	0.02	enet	45	0.03	6.7e-03	6.9	-6.2	5.0e-10	-0.77	0.30	0.23	FALSE
93	PL2	Snx16	intron excision ratio	chr2:91354845:91356529	0.13	0.04	blup	2053	0.06	3.2e-04	6.9	-6.2	4.7e-10	-0.76	0.53	0.44	FALSE
94	PL2	Tpd52	mRNA stability	ENSRNOG00000011441	0.13	0.05	top1	1	0.05	1.3e-03	-5.5	-5.5	3.2e-08	-0.77	0.11	0.04	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.