Hub : Traits : Extensor digitorum longus weight : ← : →

chr2:89,673,058-95,023,945

Trait: Extensor digitorum longus weight

Best TWAS P=1.83e-13 · Best GWAS P=1.02e-13 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Tpd52	alternative polyA	ENSRNOT00000120271	0.05	1	0.02	3.4e-03	7.32	2.46e-13	0.04	FALSE
Adipose	Tpd52	alternative polyA	ENSRNOT00000099506	0.05	1	0.02	3.7e-03	-7.32	2.46e-13	0.04	FALSE
Adipose	Tpd52	alternative polyA	ENSRNOT00000120271	0.05	1	0.02	3.8e-03	7.32	2.46e-13	0.04	FALSE
Adipose	Tpd52	alternative TSS	ENSRNOT00000120271	0.04	1	0.01	1.0e-02	-6.96	3.34e-12	0.03	FALSE
Adipose	Zbtb10	alternative TSS	ENSRNOT00000081553	0.29	27	0.19	2.7e-20	-7.02	2.17e-12	0.54	FALSE
Adipose	Zbtb10	alternative TSS	ENSRNOT00000087598	0.28	16	0.19	2.6e-20	6.99	2.82e-12	0.54	FALSE
Adipose	Snx16	gene expression	ENSRNOG00000009953	0.11	157	0.06	1.2e-07	-5.74	9.25e-09	0	FALSE
Adipose	Fabp12	gene expression	ENSRNOG00000038825	0.14	1	0.08	3.2e-09	-7	2.58e-12	0.77	FALSE
Adipose	Hey1	gene expression	ENSRNOG00000062882	0.04	2629	0.02	5.5e-03	-6.73	1.72e-11	0.28	FALSE
Adipose	Snx16	isoform ratio	ENSRNOT00000083909	0.03	1	0.01	2.5e-02	6.89	5.41e-12	0.03	FALSE
Adipose	Tpd52	isoform ratio	ENSRNOT00000120271	0.05	1	0.02	1.5e-03	5.25	1.54e-07	0.03	FALSE
Adipose	Zbtb10	isoform ratio	ENSRNOT00000081553	0.25	5	0.16	4.9e-17	-7.03	2.14e-12	0.53	FALSE
Adipose	Zbtb10	isoform ratio	ENSRNOT00000087598	0.23	2314	0.15	1.4e-16	7.23	4.82e-13	0.54	FALSE
Adipose	Fabp4	mRNA stability	ENSRNOG00000010805	0.05	1	0.03	3.2e-04	6.89	5.41e-12	0.09	FALSE
BLA	Fabp4	gene expression	ENSRNOG00000010805	0.41	10	0.24	2.8e-13	6.4	1.51e-10	0.47	FALSE
BLA	Pmp2	gene expression	ENSRNOG00000022707	0.1	1	0.08	5.9e-05	6.44	1.18e-10	0.47	FALSE
BLA	ENSRNOG00000049075	gene expression	ENSRNOG00000049075	0.2	2083	0.08	3.5e-05	6.51	7.62e-11	0.33	FALSE
BLA	Zfp704	gene expression	ENSRNOG00000054426	0.08	2020	0.03	7.8e-03	-5.9	3.64e-09	0.14	FALSE
BLA	Pag1	gene expression	ENSRNOG00000061328	0.06	1	0.01	1.2e-01	-6.45	1.13e-10	0.04	FALSE
BLA	Hey1	gene expression	ENSRNOG00000062882	0.07	1	0.03	1.5e-02	7.32	2.55e-13	0.04	FALSE
BLA	ENSRNOG00000066286	gene expression	ENSRNOG00000066286	0.06	20	0.02	2.0e-02	-6.61	3.73e-11	0.12	FALSE
BLA	Slc10a5	gene expression	ENSRNOG00000067758	0.16	1	0.08	5.3e-05	-6.97	3.28e-12	0.14	FALSE
BLA	Snx16	isoform ratio	ENSRNOT00000050987	0.09	2053	0.04	2.6e-03	-6.07	1.25e-09	0.33	FALSE
BLA	Snx16	isoform ratio	ENSRNOT00000096600	0.1	1	0.04	2.8e-03	6.59	4.35e-11	0.04	FALSE
BLA	Tpd52	isoform ratio	ENSRNOT00000099506	0.08	1	0.05	1.8e-03	-5.51	3.52e-08	0.04	FALSE
BLA	Tpd52	isoform ratio	ENSRNOT00000117383	0.06	1	0.04	4.3e-03	5.51	3.52e-08	0.04	FALSE
BLA	Zfp704	mRNA stability	ENSRNOG00000054426	0.08	2020	0.03	1.3e-02	-6.13	8.61e-10	0.16	FALSE
Brain	Tpd52	alternative polyA	ENSRNOT00000099506	0.12	1	0.05	2.0e-05	-5.51	3.63e-08	0.03	FALSE
Brain	Tpd52	alternative polyA	ENSRNOT00000117383	0.05	1	0.02	6.6e-03	5.51	3.63e-08	0.03	FALSE
Brain	Fabp4	gene expression	ENSRNOG00000010805	0.18	1	0.1	6.0e-10	6.44	1.16e-10	0.09	FALSE
Brain	ENSRNOG00000049075	gene expression	ENSRNOG00000049075	0.23	1	0.15	6.3e-14	7.17	7.32e-13	0.88	FALSE
Brain	Zfp704	gene expression	ENSRNOG00000054426	0.03	1	0.01	2.3e-02	-7.36	1.83e-13	0.04	TRUE
Brain	ENSRNOG00000066793	gene expression	ENSRNOG00000066793	0.04	1	0.01	1.5e-02	-6.29	3.19e-10	0.03	FALSE
Brain	Slc10a5	gene expression	ENSRNOG00000067758	0.24	1993	0.18	2.7e-16	-5.14	2.72e-07	0.05	FALSE
Brain	Snx16	isoform ratio	ENSRNOT00000083909	0.09	1	0.05	1.7e-05	6.29	3.19e-10	0.03	FALSE
Brain	Tpd52	isoform ratio	ENSRNOT00000099506	0.11	1	0.04	1.8e-04	-5.51	3.63e-08	0.03	FALSE
Brain	Tpd52	isoform ratio	ENSRNOT00000117383	0.03	45	0	1.6e-01	6.68	2.34e-11	0.24	FALSE
Brain	Snx16	intron excision ratio	chr2:91354845:91356529	0.14	1	0.08	1.3e-07	-6.63	3.40e-11	0.21	FALSE
Brain	Tpd52	intron excision ratio	chr2:92804650:92812941	0.04	2108	0.01	1.9e-02	5.48	4.19e-08	0.28	FALSE
Brain	Tpd52	intron excision ratio	chr2:92805700:92811676	0.04	1	0.01	1.5e-02	-7.35	1.92e-13	0.04	FALSE
Brain	Zbtb10	intron excision ratio	chr2:92498889:92508405	0.03	1	-0	4.5e-01	-7.09	1.31e-12	0.03	FALSE
Brain	Tpd52	mRNA stability	ENSRNOG00000011441	0.23	1	0.11	2.2e-10	-5.55	2.87e-08	0	FALSE
Brain	Mrps28	mRNA stability	ENSRNOG00000032630	0.08	2057	0.03	1.8e-03	6.8	1.03e-11	0.34	FALSE
Brain	Zfp704	mRNA stability	ENSRNOG00000054426	0.07	1	0.05	2.6e-05	-7.1	1.23e-12	0.17	FALSE
Eye	Fabp12	intron excision ratio	chr2:91551040:91553236	0.43	1926	0.26	6.9e-05	-5.76	8.32e-09	0.33	FALSE
Eye	Tpd52	mRNA stability	ENSRNOG00000011441	0.31	16	0.21	3.5e-04	-5.52	3.46e-08	0.19	FALSE
IL	Zc2hc1a	alternative polyA	ENSRNOT00000095126	0.29	2421	0.01	1.9e-01	-5.76	8.26e-09	0.25	FALSE
IL	Zc2hc1a	alternative polyA	ENSRNOT00000095126	0.34	2421	0.02	9.7e-02	-5.43	5.63e-08	0.29	FALSE
IL	Zc2hc1a	alternative polyA	ENSRNOT00000109624	0.3	2421	0.01	1.9e-01	5.43	5.75e-08	0.25	FALSE
IL	Fabp4	gene expression	ENSRNOG00000010805	0.76	6	0.17	5.7e-05	6.88	5.93e-12	0.62	FALSE
IL	ENSRNOG00000049075	gene expression	ENSRNOG00000049075	0.27	1	0.09	4.0e-03	6.41	1.45e-10	0.05	FALSE
IL	Tpd52	mRNA stability	ENSRNOG00000011441	0.3	1	0.12	7.2e-04	-7.32	2.42e-13	0.06	FALSE
LHb	Tpd52	mRNA stability	ENSRNOG00000011441	0.27	1	0.08	6.7e-03	-5.45	5.15e-08	0.05	FALSE
Liver	Snx16	alternative TSS	ENSRNOT00000083909	0.02	1	0	1.3e-01	-5.14	2.78e-07	0.03	FALSE
Liver	Snx16	alternative TSS	ENSRNOT00000083909	0.03	1	0.01	1.4e-02	-5.14	2.78e-07	0.03	FALSE
Liver	Snx16	alternative TSS	ENSRNOT00000096600	0.03	2050	0.01	3.7e-02	6.21	5.46e-10	0.3	FALSE
Liver	Zbtb10	alternative TSS	ENSRNOT00000081553	0.11	1	0.04	3.4e-05	-6.41	1.41e-10	0.03	FALSE
Liver	Zbtb10	alternative TSS	ENSRNOT00000087598	0.09	1	0.04	6.9e-05	6.41	1.41e-10	0.03	FALSE
Liver	Fabp12	gene expression	ENSRNOG00000038825	0.79	231	0.47	1.0e-57	-5.8	6.63e-09	0	FALSE
Liver	ENSRNOG00000049075	gene expression	ENSRNOG00000049075	0.04	8	0.02	1.4e-03	6.19	5.84e-10	0.34	FALSE
Liver	Zbtb10	isoform ratio	ENSRNOT00000081553	0.16	1	0.04	3.0e-05	-6.41	1.41e-10	0.02	FALSE
Liver	Zbtb10	isoform ratio	ENSRNOT00000087598	0.15	1	0.04	7.8e-05	6.41	1.41e-10	0.03	FALSE
Liver	Fabp12	intron excision ratio	chr2:91503212:91511657	0.68	21	0.5	8.3e-63	5.27	1.39e-07	0	FALSE
Liver	Fabp12	intron excision ratio	chr2:91551040:91553236	0.5	41	0.39	1.0e-45	-5.73	9.79e-09	0	FALSE
Liver	Tpd52	mRNA stability	ENSRNOG00000011441	0.07	1	0.04	7.4e-05	-7.32	2.46e-13	0.1	FALSE
NAcc	Tpd52	alternative polyA	ENSRNOT00000099506	0.04	1	0.01	2.8e-02	-5.16	2.48e-07	0.03	FALSE
NAcc	Tpd52	alternative polyA	ENSRNOT00000120271	0.04	1	0.01	2.9e-02	5.51	3.52e-08	0.03	FALSE
NAcc	Tpd52	alternative polyA	ENSRNOT00000099506	0.06	1	0.02	7.5e-03	-5.51	3.52e-08	0.03	FALSE
NAcc	Tpd52	alternative polyA	ENSRNOT00000120271	0.06	1	0.02	7.9e-03	5.51	3.52e-08	0.03	FALSE
NAcc	Fabp4	gene expression	ENSRNOG00000010805	0.1	19	0.03	4.4e-03	6.86	6.73e-12	0.57	FALSE
NAcc	Pmp2	gene expression	ENSRNOG00000022707	0.12	1916	0.06	1.5e-05	6.54	6.04e-11	0.57	FALSE
NAcc	ENSRNOG00000049075	gene expression	ENSRNOG00000049075	0.06	2081	0.02	1.6e-02	6.2	5.52e-10	0.41	FALSE
NAcc	ENSRNOG00000066793	gene expression	ENSRNOG00000066793	0.15	86	0.08	9.2e-07	-5.88	3.98e-09	0.22	FALSE
NAcc	Snx16	isoform ratio	ENSRNOT00000083909	0.07	39	0.01	3.4e-02	6.9	5.25e-12	0.41	FALSE
NAcc	Tpd52	mRNA stability	ENSRNOG00000011441	0.12	1	0.06	4.9e-05	-5.28	1.28e-07	0.03	FALSE
OFC	Fabp4	gene expression	ENSRNOG00000010805	0.43	1	0.08	7.4e-03	6.83	8.39e-12	0.06	FALSE
OFC	Tpd52	gene expression	ENSRNOG00000011441	0.39	3	0.15	2.1e-04	-5.56	2.75e-08	0.14	FALSE
OFC	Pmp2	gene expression	ENSRNOG00000022707	0.31	17	0.03	7.2e-02	6.83	8.25e-12	0.14	FALSE
OFC	Mrps28	gene expression	ENSRNOG00000032630	0.44	1	0.11	1.5e-03	7.32	2.42e-13	0.06	FALSE
OFC	ENSRNOG00000049075	gene expression	ENSRNOG00000049075	0.37	1	0.08	6.3e-03	6.4	1.53e-10	0.05	FALSE
OFC	Hey1	gene expression	ENSRNOG00000062882	0.19	1	0.13	6.0e-04	6.82	9.24e-12	0.05	FALSE
OFC	tGap1	isoform ratio	ENSRNOT00000033404	0.44	2380	0.09	4.7e-03	5.36	8.46e-08	0.2	FALSE
OFC	tGap1	isoform ratio	ENSRNOT00000082912	0.48	2380	0.11	1.5e-03	-5.55	2.82e-08	0.26	FALSE
PL	Tpd52	alternative TSS	ENSRNOT00000015327	0.06	2108	0.02	2.0e-02	6.26	3.85e-10	0.35	FALSE
PL	Fabp4	gene expression	ENSRNOG00000010805	0.57	207	0.27	6.5e-21	6.96	3.40e-12	0.71	FALSE
PL	Pmp2	gene expression	ENSRNOG00000022707	0.11	1	0.06	4.0e-05	7.07	1.59e-12	0.55	FALSE
PL	Mrps28	gene expression	ENSRNOG00000032630	0.18	1	0.06	1.2e-05	7.36	1.91e-13	0.4	FALSE
PL	ENSRNOG00000049075	gene expression	ENSRNOG00000049075	0.33	1	0.23	1.5e-17	6.53	6.46e-11	0.09	FALSE
PL	Zbtb10	gene expression	ENSRNOG00000061862	0.04	1	0	1.3e-01	7.35	1.94e-13	0.04	FALSE
PL	Hey1	gene expression	ENSRNOG00000062882	0.14	2629	0.06	2.3e-05	7.16	7.90e-13	0.57	FALSE
PL	ENSRNOG00000066286	gene expression	ENSRNOG00000066286	0.06	2033	0.02	1.2e-02	-6.3	2.90e-10	0.19	FALSE
PL	Slc10a5	gene expression	ENSRNOG00000067758	0.06	1989	0.01	3.1e-02	-5.84	5.26e-09	0.36	FALSE
PL	Tpd52	isoform ratio	ENSRNOT00000077270	0.08	1	0.03	4.0e-03	7.12	1.07e-12	0.04	FALSE
PL	tGap1	isoform ratio	ENSRNOT00000082912	0.06	1	0.02	2.1e-02	-6.87	6.40e-12	0.04	FALSE
PL	Snx16	intron excision ratio	chr2:91354845:91356529	0.08	1	0.02	9.1e-03	-7	2.58e-12	0.07	FALSE
PL	Tpd52	mRNA stability	ENSRNOG00000011441	0.19	56	0.09	2.7e-07	-6.4	1.53e-10	0.03	FALSE
PL	Mrps28	mRNA stability	ENSRNOG00000032630	0.07	1	0.03	5.0e-03	5.51	3.63e-08	0.03	FALSE