Hub : Traits : Extensor digitorum longus weight : ← : →

chr7:29,535-2,057,232

Trait: Extensor digitorum longus weight

Best TWAS P=1.47e-07 · Best GWAS P=1.45e-07 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Cd63	alternative TSS	ENSRNOT00000114033	0.04	1	0.03	7.4e-04	5.11	3.21e-07	0.08	FALSE
Adipose	Ikzf4	gene expression	ENSRNOG00000005535	0.06	24	0.05	6.2e-06	-5.15	2.63e-07	0.72	TRUE
Adipose	Dnajc14	gene expression	ENSRNOG00000006844	0.43	27	0.29	3.8e-32	5.15	2.63e-07	0.26	FALSE
Adipose	Coq10a	gene expression	ENSRNOG00000029571	0.03	1	0.02	3.6e-03	-5.15	2.63e-07	0.04	FALSE
Adipose	Myl6	intron excision ratio	chr7:910945:911642	0.03	1046	0.02	1.9e-03	5.17	2.38e-07	0.63	FALSE
Adipose	Atp5f1b	mRNA stability	ENSRNOG00000002840	0.19	39	0.12	1.5e-13	-5.12	3.13e-07	0.78	FALSE
BLA	Gls2	alternative TSS	ENSRNOT00000099901	0.06	10	0.06	3.3e-04	5.23	1.73e-07	0.7	FALSE
BLA	Naca	gene expression	ENSRNOG00000002632	0.05	1	0.06	4.3e-04	5.16	2.51e-07	0.09	FALSE
BLA	Atp5f1b	gene expression	ENSRNOG00000002840	0.2	20	0.22	4.6e-12	-5.15	2.63e-07	0.79	FALSE
BLA	Erbb3	gene expression	ENSRNOG00000004964	0.09	1	0.12	7.2e-07	-5.15	2.63e-07	0.46	FALSE
BLA	Itga7	gene expression	ENSRNOG00000007905	0.12	13	0.11	1.4e-06	5.17	2.37e-07	0.67	FALSE
BLA	Stat2	gene expression	ENSRNOG00000031081	0.69	21	0.65	1.7e-45	-5.13	2.82e-07	0.73	FALSE
BLA	Smarcc2	gene expression	ENSRNOG00000031135	0.08	37	0.08	3.3e-05	-5.2	1.98e-07	0.68	FALSE
BLA	Esyt1	gene expression	ENSRNOG00000060753	0.18	85	0.17	1.8e-09	-5.24	1.62e-07	0.72	FALSE
BLA	ENSRNOG00000062455	gene expression	ENSRNOG00000062455	0.23	1023	0.27	1.3e-14	-5.2	2.05e-07	0.71	FALSE
BLA	Sarnp	isoform ratio	ENSRNOT00000009155	0.07	1	0.04	3.6e-03	-5.15	2.66e-07	0.06	FALSE
BLA	Rnf41	intron excision ratio	chr7:838301:841866	0.06	961	0.05	1.2e-03	5.17	2.33e-07	0.66	FALSE
BLA	Myl6	intron excision ratio	chr7:910945:911978	0.05	1	0.01	9.8e-02	-5.14	2.74e-07	0.04	FALSE
BLA	Tmem198b	mRNA stability	ENSRNOG00000006827	0.06	1	0.06	6.2e-04	-5.18	2.27e-07	0.06	FALSE
BLA	Ormdl2	mRNA stability	ENSRNOG00000030120	0.06	1388	0.05	1.5e-03	5.14	2.76e-07	0.58	FALSE
Brain	Rbms2	alternative polyA	ENSRNOT00000048848	0.05	2	0.03	3.8e-04	5.16	2.41e-07	0.7	FALSE
Brain	Rbms2	alternative polyA	ENSRNOT00000118787	0.05	1	0.04	3.3e-04	-5.15	2.64e-07	0.25	FALSE
Brain	Atp5f1b	gene expression	ENSRNOG00000002840	0.18	1	0.18	4.5e-16	-5.11	3.18e-07	0.77	FALSE
Brain	Tmem198b	gene expression	ENSRNOG00000006827	0.06	1	0.04	1.4e-04	5.15	2.66e-07	0.23	FALSE
Brain	Itga7	gene expression	ENSRNOG00000007905	0.16	16	0.13	4.1e-12	5.12	3.07e-07	0.69	FALSE
Brain	Sarnp	gene expression	ENSRNOG00000030520	0.03	1	0.02	2.3e-03	5.26	1.47e-07	0.05	TRUE
Brain	Ptges3	isoform ratio	ENSRNOT00000101866	0.06	1	0.04	6.2e-05	-5.21	1.91e-07	0.58	FALSE
Brain	Bloc1s1	isoform ratio	ENSRNOT00000010380	0.11	1	0.08	4.4e-08	-5.15	2.66e-07	0.71	FALSE
Brain	Rnf41	intron excision ratio	chr7:838383:841866	0.52	35	0.08	7.3e-08	-5.16	2.45e-07	0.72	FALSE
Brain	Smarcc2	intron excision ratio	chr7:902231:902576	0.03	1	0.01	2.2e-02	5.14	2.78e-07	0.06	FALSE
Brain	Ikzf4	mRNA stability	ENSRNOG00000005535	0.03	1	0.02	5.5e-03	-5.14	2.70e-07	0.04	FALSE
Brain	Dnajc14	mRNA stability	ENSRNOG00000006844	0.37	1	0.29	2.2e-27	-5.15	2.66e-07	0.73	FALSE
Brain	Stat2	mRNA stability	ENSRNOG00000031081	0.33	1	0.34	1.2e-32	-5.19	2.05e-07	0.77	FALSE
IL	Dgka	gene expression	ENSRNOG00000022943	0.3	18	0.08	5.5e-03	-5.11	3.22e-07	0.51	FALSE
IL	Myl6	gene expression	ENSRNOG00000054140	0.38	1041	0.13	5.4e-04	-5.12	3.01e-07	0.54	FALSE
IL	Esyt1	gene expression	ENSRNOG00000060753	0.16	1	0.02	1.2e-01	-5.13	2.93e-07	0.06	FALSE
IL	Dnajc14	mRNA stability	ENSRNOG00000006844	0.66	4	0.25	1.2e-06	-5.19	2.12e-07	0.69	TRUE
LHb	Cd63	alternative TSS	ENSRNOT00000090381	0.18	1	0.2	2.0e-05	5.09	3.50e-07	0.07	FALSE
LHb	Itga7	gene expression	ENSRNOG00000007905	0.26	1443	0.11	1.2e-03	5.13	2.94e-07	0.57	FALSE
Liver	Rbms2	alternative polyA	ENSRNOT00000118787	0.02	1	0.01	9.2e-03	-5.11	3.18e-07	0.03	FALSE
Liver	Dgka	gene expression	ENSRNOG00000022943	0.34	1282	0.28	1.4e-31	5.14	2.75e-07	0.73	FALSE
Liver	AC128207.1	gene expression	ENSRNOG00000028837	0.05	1	0.04	3.9e-05	-5.21	1.91e-07	0.46	FALSE
Liver	Timeless	gene expression	ENSRNOG00000031916	0.24	934	0.23	8.1e-25	5.1	3.46e-07	0.71	FALSE
Liver	Rbms2	isoform ratio	ENSRNOT00000048848	0.02	1	0.02	2.5e-03	5.11	3.18e-07	0.04	FALSE
Liver	Sarnp	intron excision ratio	chr7:1251291:1261739	0.03	1	0.02	3.1e-03	5.12	3.02e-07	0.04	FALSE
Liver	Sarnp	intron excision ratio	chr7:1254119:1261739	0.04	1386	0.02	2.4e-03	-5.14	2.79e-07	0.67	FALSE
Liver	Pa2g4	mRNA stability	ENSRNOG00000004904	0.02	1	0.01	2.5e-02	5.14	2.78e-07	0.03	FALSE
Liver	Dgka	mRNA stability	ENSRNOG00000022943	0.14	1282	0.09	4.5e-10	5.14	2.71e-07	0.72	FALSE
NAcc	Rbms2	alternative polyA	ENSRNOT00000048848	0.08	1	0.07	4.0e-06	5.24	1.59e-07	0.79	FALSE
NAcc	Rbms2	alternative polyA	ENSRNOT00000118787	0.07	1	0.07	8.9e-06	-5.22	1.75e-07	0.74	FALSE
NAcc	Suox	alternative TSS	ENSRNOT00000008018	0.03	1	0.04	1.2e-03	5.24	1.59e-07	0.05	FALSE
NAcc	Suox	alternative TSS	ENSRNOT00000108072	0.04	1	0.04	6.1e-04	-5.2	1.95e-07	0.06	FALSE
NAcc	Myl6	alternative TSS	ENSRNOT00000082518	0.05	1	0.04	5.1e-04	-5.19	2.05e-07	0.15	FALSE
NAcc	Myl6	alternative TSS	ENSRNOT00000099810	0.04	1	0.03	1.8e-03	5.19	2.05e-07	0.09	FALSE
NAcc	Atp5f1b	gene expression	ENSRNOG00000002840	0.05	1	0.05	1.0e-04	-5.24	1.59e-07	0.38	FALSE
NAcc	Tmem198b	gene expression	ENSRNOG00000006827	0.05	1397	0.03	3.3e-03	5.12	2.99e-07	0.61	FALSE
NAcc	Stat2	gene expression	ENSRNOG00000031081	0.81	33	0.34	8.9e-26	-5.13	2.88e-07	0.72	FALSE
NAcc	Rbms2	isoform ratio	ENSRNOT00000048848	0.11	1	0.1	1.1e-07	5.24	1.59e-07	0.82	FALSE
NAcc	Rbms2	isoform ratio	ENSRNOT00000088619	0.07	1	0.05	8.0e-05	-5.24	1.59e-07	0.3	FALSE
NAcc	Cnpy2	isoform ratio	ENSRNOT00000004895	0.07	1	0.05	1.2e-04	5.16	2.51e-07	0.41	FALSE
NAcc	Rab5b	mRNA stability	ENSRNOG00000006130	0.03	1145	0.03	5.3e-03	5.11	3.16e-07	0.49	TRUE
NAcc	Dnajc14	mRNA stability	ENSRNOG00000006844	0.43	14	0.35	7.6e-27	-5.18	2.27e-07	0.72	FALSE
NAcc	Stat2	mRNA stability	ENSRNOG00000031081	0.16	29	0.16	6.0e-12	-5.13	2.93e-07	0.71	FALSE
OFC	Myl6	gene expression	ENSRNOG00000054140	0.31	1041	0.19	2.7e-05	-5.12	3.03e-07	0.6	FALSE
OFC	Esyt1	gene expression	ENSRNOG00000060753	0.26	1	0.15	2.2e-04	-5.13	2.93e-07	0.07	FALSE
OFC	ENSRNOG00000062455	gene expression	ENSRNOG00000062455	0.15	1019	0.07	8.9e-03	-5.11	3.26e-07	0.45	FALSE
OFC	Stat2	mRNA stability	ENSRNOG00000031081	0.37	1	0.27	3.7e-07	-5.24	1.59e-07	0.54	FALSE
PL	Sarnp	alternative TSS	ENSRNOT00000096123	0.04	9	0.01	4.0e-02	5.14	2.69e-07	0.59	FALSE
PL	Tmem198b	gene expression	ENSRNOG00000006827	0.05	1397	0.04	9.5e-04	5.14	2.73e-07	0.62	FALSE
PL	Stat2	gene expression	ENSRNOG00000031081	0.72	939	0.63	1.7e-60	-5.16	2.45e-07	0.73	FALSE
PL	Smarcc2	gene expression	ENSRNOG00000031135	0.03	1040	0.02	9.9e-03	-5.18	2.24e-07	0.5	FALSE
PL	Zc3h10	gene expression	ENSRNOG00000040281	0.04	1044	0.05	1.3e-04	5.18	2.24e-07	0.64	FALSE
PL	Baz2a	gene expression	ENSRNOG00000053881	0.06	1	0.06	2.7e-05	-5.22	1.75e-07	0.42	FALSE
PL	Esyt1	gene expression	ENSRNOG00000060753	0.18	9	0.17	4.7e-13	-5.14	2.69e-07	0.71	FALSE
PL	Rnf41	intron excision ratio	chr7:838301:840354	0.17	1	0.13	9.3e-10	5.2	1.95e-07	0.77	FALSE
PL	Rnf41	intron excision ratio	chr7:838301:841866	0.03	1	0.02	2.0e-02	5.12	3.07e-07	0.04	FALSE
PL	Prim1	intron excision ratio	chr7:446523:449427	0.22	6	0.19	1.6e-14	5.16	2.52e-07	0.81	FALSE
PL	Myl6	intron excision ratio	chr7:910945:911642	0.04	1	0.04	5.1e-04	5.21	1.91e-07	0.06	FALSE
PL	Myl6	intron excision ratio	chr7:910945:911978	0.08	1	0.07	4.8e-06	-5.21	1.91e-07	0.57	FALSE
PL	Myl6	intron excision ratio	chr7:911686:911978	0.06	2	0.06	5.2e-05	5.24	1.60e-07	0.67	FALSE
PL	Dnajc14	mRNA stability	ENSRNOG00000006844	0.43	1	0.33	2.2e-25	-5.18	2.27e-07	0.76	FALSE
PL	Dgka	mRNA stability	ENSRNOG00000022943	0.08	1283	0.07	7.0e-06	5.15	2.60e-07	0.69	FALSE