chr5:59,359,307-62,635,773

Trait: Extensor digitorum longus weight

Best TWAS P = 3.84e-08 · Best GWAS P= 2.99e-08 conditioned to 2.37e-83

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Brain Dcaf12 gene expression Dcaf12 0.19 139 0.11 1.5e-10 -5.39 7.16e-08 0.73 FALSE
LHb Phf24 isoform ratio NM_001398835.1 0.47 118 0.35 4.3e-09 -5.35 8.88e-08 0.44 FALSE
Liver Ccl21 gene expression Ccl21 0.09 191 0.11 8.9e-12 -5.28 1.30e-07 0.75 FALSE
Liver Ndufb6 mRNA stability Ndufb6 0.03 2308 0.02 2.2e-03 -5.24 1.62e-07 0.42 FALSE
Liver Rig1 mRNA stability Rig1 0.05 4 0.01 7.9e-03 5.5 3.84e-08 0.42 TRUE
PL Aco1 gene expression Aco1 0.07 4 0.04 1.2e-05 5.29 1.22e-07 0.45 FALSE
PL Dcaf12 gene expression Dcaf12 0.05 48 0.03 2.0e-04 -5.41 6.26e-08 0.68 FALSE
pVTA Ccl27 intron excision ratio chr5_61738956_61741152 0.03 23 0.03 2.9e-03 -5.34 9.05e-08 0.37 FALSE