Hub : Traits : EDL weight in grams : ← →

chr7:29,535-2,057,232

Best TWAS P=1.471503e-07 · Best GWAS P=1.453537e-07 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Cd63	alternative TSS	ENSRNOT00000114033	0.04	0.03	top1	1	0.03	7.4e-04	5.1	5.1	3.2e-07	0.95	0.06	0.08	FALSE
2	Adipose	Ikzf4	gene expression	ENSRNOG00000005535	0.06	0.05	lasso	24	0.05	6.2e-06	5.1	-5.1	2.6e-07	-0.78	0.28	0.72	TRUE
3	Adipose	Dnajc14	gene expression	ENSRNOG00000006844	0.43	0.27	lasso	27	0.29	3.8e-32	4.3	5.1	2.6e-07	-0.86	0.74	0.26	FALSE
4	Adipose	Coq10a	gene expression	ENSRNOG00000029571	0.03	0.02	top1	1	0.02	3.6e-03	5.1	-5.1	2.6e-07	-0.97	0.03	0.04	FALSE
5	Adipose	Myl6	intron excision ratio	chr7:910945:911642	0.03	0.01	blup	1046	0.02	1.9e-03	5.1	5.2	2.4e-07	0.97	0.33	0.63	FALSE
6	Adipose	Atp5f1b	mRNA stability	ENSRNOG00000002840	0.19	0.12	lasso	39	0.12	1.5e-13	5.2	-5.1	3.1e-07	-0.96	0.22	0.78	FALSE
7	BLA	Gls2	alternative TSS	ENSRNOT00000099901	0.06	0.05	enet	10	0.06	3.3e-04	5.2	5.2	1.7e-07	1.00	0.27	0.70	FALSE
8	BLA	Naca	gene expression	ENSRNOG00000002632	0.05	0.06	top1	1	0.06	4.3e-04	5.2	5.2	2.5e-07	0.96	0.04	0.09	FALSE
9	BLA	Atp5f1b	gene expression	ENSRNOG00000002840	0.20	0.20	lasso	20	0.22	4.6e-12	5.2	-5.1	2.6e-07	-0.95	0.21	0.79	FALSE
10	BLA	Erbb3	gene expression	ENSRNOG00000004964	0.09	0.12	top1	1	0.12	7.2e-07	5.1	-5.1	2.6e-07	-0.98	0.20	0.46	FALSE
11	BLA	Itga7	gene expression	ENSRNOG00000007905	0.12	0.10	lasso	13	0.11	1.4e-06	5.2	5.2	2.4e-07	1.00	0.33	0.67	FALSE
12	BLA	Stat2	gene expression	ENSRNOG00000031081	0.69	0.58	lasso	21	0.65	1.7e-45	5.1	-5.1	2.8e-07	-0.95	0.27	0.73	FALSE
13	BLA	Smarcc2	gene expression	ENSRNOG00000031135	0.08	0.08	enet	37	0.08	3.3e-05	5.2	-5.2	2.0e-07	-0.95	0.32	0.68	FALSE
14	BLA	Esyt1	gene expression	ENSRNOG00000060753	0.18	0.17	enet	85	0.17	1.8e-09	5.2	-5.2	1.6e-07	-0.96	0.28	0.72	FALSE
15	BLA	NA	gene expression	ENSRNOG00000062455	0.23	0.24	blup	1023	0.27	1.3e-14	5.3	-5.2	2.0e-07	-0.99	0.29	0.71	FALSE
16	BLA	Sarnp	isoform ratio	ENSRNOT00000009155	0.07	0.04	top1	1	0.04	3.6e-03	5.1	-5.1	2.7e-07	-0.99	0.06	0.06	FALSE
17	BLA	Rnf41	intron excision ratio	chr7:838301:841866	0.06	0.05	blup	961	0.05	1.2e-03	5.1	5.2	2.3e-07	0.98	0.28	0.66	FALSE
18	BLA	Myl6	intron excision ratio	chr7:910945:911978	0.05	0.01	top1	1	0.01	9.8e-02	5.1	-5.1	2.7e-07	-0.96	0.04	0.04	FALSE
19	BLA	Tmem198b	mRNA stability	ENSRNOG00000006827	0.06	0.06	top1	1	0.06	6.2e-04	5.2	-5.2	2.3e-07	-0.96	0.06	0.06	FALSE
20	BLA	Ormdl2	mRNA stability	ENSRNOG00000030120	0.06	0.04	blup	1388	0.05	1.5e-03	5.1	5.1	2.8e-07	0.99	0.30	0.58	FALSE
21	Brain	Rbms2	alternative polyA	ENSRNOT00000048848	0.05	0.03	lasso	2	0.03	3.8e-04	5.1	5.2	2.4e-07	0.93	0.28	0.70	FALSE
22	Brain	Rbms2	alternative polyA	ENSRNOT00000118787	0.05	0.03	top1	1	0.04	3.3e-04	5.1	-5.1	2.6e-07	-0.96	0.09	0.25	FALSE
23	Brain	Atp5f1b	gene expression	ENSRNOG00000002840	0.18	0.18	top1	1	0.18	4.5e-16	5.1	-5.1	3.2e-07	-0.96	0.23	0.77	FALSE
24	Brain	Tmem198b	gene expression	ENSRNOG00000006827	0.06	0.04	top1	1	0.04	1.4e-04	5.1	5.1	2.7e-07	0.97	0.11	0.23	FALSE
25	Brain	Itga7	gene expression	ENSRNOG00000007905	0.16	0.13	lasso	16	0.13	4.1e-12	5.1	5.1	3.1e-07	0.98	0.31	0.69	FALSE
26	Brain	Sarnp	gene expression	ENSRNOG00000030520	0.03	0.02	top1	1	0.02	2.3e-03	5.3	5.3	1.5e-07	0.98	0.05	0.05	TRUE
27	Brain	Ptges3	isoform ratio	ENSRNOT00000101866	0.06	0.04	top1	1	0.04	6.2e-05	5.2	-5.2	1.9e-07	-0.96	0.11	0.58	FALSE
28	Brain	Bloc1s1	isoform ratio	ENSRNOT00000010380	0.11	0.08	top1	1	0.08	4.4e-08	5.1	-5.1	2.7e-07	-0.99	0.28	0.71	FALSE
29	Brain	Rnf41	intron excision ratio	chr7:838383:841866	0.52	0.08	lasso	35	0.08	7.3e-08	5.1	-5.2	2.4e-07	-0.95	0.28	0.72	FALSE
30	Brain	Smarcc2	intron excision ratio	chr7:902231:902576	0.03	0.01	top1	1	0.01	2.2e-02	5.1	5.1	2.8e-07	0.98	0.04	0.06	FALSE
31	Brain	Ikzf4	mRNA stability	ENSRNOG00000005535	0.03	0.02	top1	1	0.02	5.5e-03	5.1	-5.1	2.7e-07	-0.99	0.04	0.04	FALSE
32	Brain	Dnajc14	mRNA stability	ENSRNOG00000006844	0.37	0.29	top1	1	0.29	2.2e-27	5.1	-5.1	2.7e-07	-0.99	0.27	0.73	FALSE
33	Brain	Stat2	mRNA stability	ENSRNOG00000031081	0.33	0.34	top1	1	0.34	1.2e-32	5.2	-5.2	2.0e-07	-0.97	0.23	0.77	FALSE
34	IL	Dgka	gene expression	ENSRNOG00000022943	0.30	0.07	enet	18	0.08	5.5e-03	5.1	-5.1	3.2e-07	-0.96	0.25	0.51	FALSE
35	IL	Myl6	gene expression	ENSRNOG00000054140	0.38	0.12	blup	1041	0.13	5.4e-04	4.4	-5.1	3.0e-07	-0.96	0.36	0.54	FALSE
36	IL	Esyt1	gene expression	ENSRNOG00000060753	0.16	0.02	top1	1	0.02	1.2e-01	5.1	-5.1	2.9e-07	-0.97	0.06	0.06	FALSE
37	IL	Dnajc14	mRNA stability	ENSRNOG00000006844	0.66	0.24	lasso	4	0.25	1.2e-06	5.1	-5.2	2.1e-07	0.87	0.30	0.69	TRUE
38	LHb	Itga7	gene expression	ENSRNOG00000007905	0.26	0.10	blup	1443	0.11	1.2e-03	5.0	5.1	2.9e-07	0.99	0.36	0.57	FALSE
39	Liver	Rbms2	alternative polyA	ENSRNOT00000118787	0.02	0.01	top1	1	0.01	9.2e-03	5.1	-5.1	3.2e-07	-0.96	0.03	0.03	FALSE
40	Liver	Dgka	gene expression	ENSRNOG00000022943	0.34	0.27	blup	1282	0.28	1.4e-31	5.1	5.1	2.7e-07	0.97	0.27	0.73	FALSE
41	Liver	AC128207.1	gene expression	ENSRNOG00000028837	0.05	0.04	top1	1	0.04	3.9e-05	5.2	-5.2	1.9e-07	-0.98	0.16	0.46	FALSE
42	Liver	Rbms2	isoform ratio	ENSRNOT00000048848	0.02	0.02	top1	1	0.02	2.5e-03	5.1	5.1	3.2e-07	0.96	0.03	0.04	FALSE
43	Liver	Sarnp	intron excision ratio	chr7:1251291:1261739	0.03	0.02	top1	1	0.02	3.1e-03	5.1	5.1	3.0e-07	0.98	0.04	0.04	FALSE
44	Liver	Sarnp	intron excision ratio	chr7:1254119:1261739	0.04	0.02	blup	1386	0.02	2.4e-03	5.1	-5.1	2.8e-07	-0.99	0.29	0.67	FALSE
45	Liver	Pa2g4	mRNA stability	ENSRNOG00000004904	0.02	0.01	top1	1	0.01	2.5e-02	5.1	5.1	2.8e-07	0.99	0.03	0.03	FALSE
46	Liver	Dgka	mRNA stability	ENSRNOG00000022943	0.14	0.09	blup	1282	0.09	4.5e-10	5.1	5.1	2.7e-07	0.98	0.28	0.72	FALSE
47	NAcc	Atp5f1b	gene expression	ENSRNOG00000002840	0.16	0.09	top1	1	0.09	5.8e-03	5.1	-5.1	2.6e-07	-0.96	0.04	0.06	FALSE
48	NAcc	Stat2	gene expression	ENSRNOG00000031081	0.23	0.11	top1	1	0.11	1.9e-03	5.1	-5.1	3.1e-07	-0.97	0.06	0.07	FALSE
49	NAcc	Esyt1	gene expression	ENSRNOG00000060753	0.18	0.14	top1	1	0.14	5.0e-04	5.1	-5.1	2.9e-07	-0.98	0.06	0.06	FALSE
50	NAcc	Rab5b	intron excision ratio	chr7:1119062:1119825	0.17	0.06	top1	1	0.06	1.5e-02	5.2	-5.2	1.7e-07	-0.99	0.06	0.06	FALSE
51	NAcc	Dnajc14	mRNA stability	ENSRNOG00000006844	0.34	0.20	top1	1	0.20	2.8e-05	5.3	-5.3	1.5e-07	-0.97	0.09	0.17	FALSE
52	NAcc2	Cnpy2	alternative polyA	ENSRNOT00000105756	0.16	0.13	blup	939	0.15	1.2e-08	5.1	-5.1	3.2e-07	-0.95	0.30	0.70	FALSE
53	NAcc2	Pa2g4	alternative polyA	ENSRNOT00000006578	0.05	0.01	lasso	11	0.03	1.7e-02	5.2	-5.2	2.5e-07	-0.95	0.24	0.50	FALSE
54	NAcc2	Bloc1s1	alternative TSS	ENSRNOT00000105370	0.05	0.02	lasso	10	0.03	1.4e-02	5.2	5.2	1.6e-07	0.96	0.30	0.51	FALSE
55	NAcc2	Myl6	alternative TSS	ENSRNOT00000099810	0.06	0.03	enet	24	0.03	5.8e-03	4.6	5.1	3.3e-07	0.95	0.39	0.51	TRUE
56	NAcc2	Ptges3	gene expression	ENSRNOG00000002642	0.06	0.06	top1	1	0.06	2.1e-04	5.1	5.1	3.2e-07	0.96	0.04	0.07	FALSE
57	NAcc2	Erbb3	gene expression	ENSRNOG00000004964	0.06	0.06	top1	1	0.06	4.8e-04	5.1	-5.1	2.6e-07	-0.98	0.06	0.08	FALSE
58	NAcc2	Stat2	gene expression	ENSRNOG00000031081	0.50	0.28	enet	38	0.34	8.1e-19	5.2	-5.2	2.3e-07	-0.98	0.26	0.74	FALSE
59	NAcc2	Zc3h10	gene expression	ENSRNOG00000040281	0.07	0.04	top1	1	0.04	2.3e-03	5.2	5.2	1.8e-07	0.97	0.05	0.08	FALSE
60	NAcc2	Myl6	gene expression	ENSRNOG00000054140	0.05	0.04	top1	1	0.04	3.3e-03	5.1	-5.1	2.7e-07	-0.98	0.05	0.05	FALSE
61	NAcc2	Esyt1	gene expression	ENSRNOG00000060753	0.16	0.18	top1	1	0.18	5.2e-10	5.2	-5.2	2.0e-07	-0.98	0.26	0.74	FALSE
62	NAcc2	Rbms2	isoform ratio	ENSRNOT00000048848	0.14	0.11	top1	1	0.11	2.4e-06	5.2	5.2	2.5e-07	0.96	0.22	0.68	FALSE
63	NAcc2	Rbms2	isoform ratio	ENSRNOT00000088619	0.07	0.08	top1	1	0.08	2.7e-05	5.1	-5.1	3.2e-07	-0.96	0.07	0.13	FALSE
64	NAcc2	Rbms2	isoform ratio	ENSRNOT00000118787	0.06	0.02	top1	1	0.02	2.0e-02	5.1	-5.1	2.7e-07	-0.96	0.04	0.05	FALSE
65	NAcc2	Cnpy2	isoform ratio	ENSRNOT00000004895	0.09	0.08	top1	1	0.08	4.6e-05	5.2	5.2	1.8e-07	0.97	0.09	0.27	FALSE
66	NAcc2	Cnpy2	isoform ratio	ENSRNOT00000105756	0.08	0.06	blup	939	0.06	3.4e-04	5.1	-5.1	2.6e-07	-0.96	0.30	0.68	FALSE
67	NAcc2	Sarnp	intron excision ratio	chr7:1280052:1300213	0.10	0.09	top1	1	0.09	9.6e-06	5.1	-5.1	2.7e-07	-0.99	0.12	0.25	FALSE
68	NAcc2	Dnajc14	mRNA stability	ENSRNOG00000006844	0.45	0.36	lasso	3	0.37	4.0e-21	5.2	-5.2	2.3e-07	-1.00	0.30	0.70	FALSE
69	OFC	Myl6	gene expression	ENSRNOG00000054140	0.31	0.18	blup	1041	0.19	2.7e-05	5.1	-5.1	3.0e-07	-0.95	0.37	0.60	FALSE
70	OFC	Esyt1	gene expression	ENSRNOG00000060753	0.26	0.15	top1	1	0.15	2.2e-04	5.1	-5.1	2.9e-07	-0.97	0.06	0.07	FALSE
71	OFC	NA	gene expression	ENSRNOG00000062455	0.15	0.06	blup	1019	0.07	8.9e-03	5.1	-5.1	3.3e-07	-0.98	0.24	0.45	FALSE
72	OFC	Stat2	mRNA stability	ENSRNOG00000031081	0.37	0.27	top1	1	0.27	3.7e-07	5.2	-5.2	1.6e-07	-0.97	0.14	0.54	FALSE
73	PL	Ikzf4	gene expression	ENSRNOG00000005535	0.22	0.06	lasso	2	0.09	3.3e-03	5.1	-5.1	3.0e-07	-0.98	0.26	0.49	FALSE
74	PL2	Sarnp	alternative TSS	ENSRNOT00000096123	0.06	0.05	top1	1	0.05	1.2e-03	5.1	5.1	2.6e-07	0.97	0.06	0.05	FALSE
75	PL2	Stat2	gene expression	ENSRNOG00000031081	0.68	0.50	blup	939	0.56	1.5e-36	5.1	-5.2	2.2e-07	-0.97	0.26	0.74	FALSE
76	PL2	Smarcc2	gene expression	ENSRNOG00000031135	0.08	0.07	blup	1040	0.08	4.8e-05	5.1	-5.2	2.1e-07	-0.98	0.31	0.68	FALSE
77	PL2	Zc3h10	gene expression	ENSRNOG00000040281	0.08	0.07	enet	131	0.07	1.5e-04	5.2	5.2	1.9e-07	1.00	0.30	0.69	FALSE
78	PL2	Prim1	intron excision ratio	chr7:446523:449427	0.23	0.15	blup	619	0.17	9.4e-10	5.1	5.1	3.0e-07	0.94	0.19	0.81	FALSE
79	PL2	Myl6	intron excision ratio	chr7:910945:911978	0.06	0.03	top1	1	0.03	8.8e-03	5.1	-5.1	3.1e-07	-0.97	0.04	0.04	FALSE
80	PL2	Myl6	intron excision ratio	chr7:911686:911978	0.06	0.03	top1	1	0.03	8.0e-03	5.1	5.1	3.1e-07	0.97	0.04	0.04	FALSE
81	PL2	Dgka	mRNA stability	ENSRNOG00000022943	0.08	0.06	top1	1	0.06	4.7e-04	5.1	5.1	2.6e-07	0.99	0.06	0.06	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.