chr1:181,162,118-184,410,771

Trait: Extensor digitorum longus weight

Best TWAS P = 3.75e-08 · Best GWAS P= 1.35e-07 conditioned to 1.34e-97

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose Iqck gene expression Iqck 0.38 11 0.27 9.2e-30 -5.47 4.59e-08 0.55 FALSE
BLA LOC120099916 gene expression LOC120099916 0.17 51 0.18 1.0e-09 5.29 1.23e-07 0.51 FALSE
BLA Syt17 isoform ratio XM_006230104.2 0.05 2706 0.02 3.2e-02 -5.43 5.76e-08 0.3 FALSE
BLA Rps15a intron excision ratio chr1_181860280_181861108 0.17 2737 0.15 3.3e-08 5.37 7.93e-08 0.19 FALSE
BLA Rps15a intron excision ratio chr1_181860280_181861215 0.11 2737 0.09 3.1e-05 -5.34 9.40e-08 0.29 FALSE
IC Eri2 intron excision ratio chr1_183578681_183579544 0.38 29 0.16 4.4e-07 5.25 1.49e-07 0.52 FALSE
IC Eri2 intron excision ratio chr1_183579177_183579544 0.38 30 0.16 4.1e-07 -5.27 1.35e-07 0.52 FALSE
IC Rps15a intron excision ratio chr1_181860280_181861108 0.09 2348 0.02 4.7e-02 5.45 5.14e-08 0.21 FALSE
Liver Gde1 gene expression Gde1 0.39 18 0.19 6.8e-21 -5.43 5.70e-08 0.53 FALSE
Liver RGD1559600 intron excision ratio chr1_183405725_183418750 0.33 41 0.01 4.9e-02 -5.31 1.09e-07 0.4 FALSE
NAcc Lyrm1 isoform ratio NM_001276487.1 0.03 22 0.02 1.6e-04 5.22 1.80e-07 0.01 FALSE
PL Rps15a intron excision ratio chr1_181860280_181861108 0.04 2737 0.04 1.4e-05 5.31 1.11e-07 0.52 FALSE
PL Rps15a intron excision ratio chr1_181860280_181861215 0.02 2737 0.02 3.0e-03 -5.38 7.33e-08 0.48 FALSE
PL Syt17 intron excision ratio chr1_182191400_182191628 0.03 2706 0.02 1.8e-03 -5.24 1.57e-07 0.52 FALSE
pVTA Gde1 gene expression Gde1 0.06 13 0.05 3.8e-05 5.5 3.75e-08 0.52 TRUE