Hub : Traits : EDL weight in grams :

chr1:171,727,837-174,685,359

Best TWAS P=1.754608e-07 · Best GWAS P=9.37038e-07 conditioned to 6.740244e-77

Associated models

# Tissue Gene Modality RNA phenotype h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 Liver Gde1 gene expression ENSRNOG00000050445 0.32 0.15 lasso 36 0.20 4.8e-22 -4.6 -5.2 1.8e-07 0.86 0.53 0.47 TRUE
2 Liver RGD1559600 intron excision ratio chr1:173974388:173987413 0.53 0.01 lasso 2 0.01 3.5e-02 -4.5 -5.2 2.0e-07 0.90 0.25 0.38 FALSE
3 PL2 Rps15a isoform ratio ENSRNOT00000092282 0.07 0.03 blup 2643 0.07 1.8e-04 -4.0 -5.2 2.1e-07 0.78 0.67 0.30 FALSE
4 PL2 Rps15a isoform ratio ENSRNOT00000092513 0.07 0.03 blup 2643 0.07 1.7e-04 -4.0 5.2 1.9e-07 -0.79 0.64 0.33 FALSE
5 PL2 Syt17 intron excision ratio chr1:172757188:172757416 0.06 0.03 blup 2590 0.04 2.5e-03 -4.5 -5.1 2.9e-07 0.78 0.52 0.37 FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.