Best TWAS P=3.117044e-08 · Best GWAS P=3.698601e-07 conditioned to 0.01391791
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Brain | Tnrc6a | gene expression | ENSRNOG00000024737 | 0.23 | 0.11 | enet | 23 | 0.14 | 8.9e-13 | -5 | 5.5 | 3.1e-08 | -0.55 | 0.19 | 0.81 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.