Hub : Traits : Bone: cortical porosity : ←

chr10:90,276,309-92,218,338

Trait: Bone: cortical porosity

Best TWAS P = 9.11e-10 · Best GWAS P= 2.67e-08 conditioned to 1e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Map3k3	isoform ratio	NM_001107058.3	0.13	1959	0.03	6.9e-04	-5.28	1.32e-07	0.54	FALSE
Adipose	Map3k3	isoform ratio	XM_063269201.1	0.13	1959	0.02	1.4e-03	5.3	1.18e-07	0.56	FALSE
BLA	Marchf10	intron excision ratio	chr10_90833054_90835012	0.11	97	0.04	2.0e-03	-5.73	9.99e-09	0.88	FALSE
BLA	Marchf10	intron excision ratio	chr10_90833054_90836248	0.2	154	0.08	7.1e-05	6.12	9.11e-10	0.91	TRUE
Brain	Marchf10	alternative polyA	XM_039086143.2	0.07	1	0.07	6.1e-07	-5.56	2.69e-08	0.94	FALSE
Brain	Marchf10	alternative polyA	XM_063269194.1	0.07	1	0.06	1.5e-06	5.56	2.69e-08	0.93	FALSE
Brain	Marchf10	alternative polyA	XM_063269194.1	0.06	1	0.03	1.0e-03	5.56	2.69e-08	0.38	FALSE
Brain	LOC134480889	intron excision ratio	chr10_90974697_91027769	0.04	40	0.02	2.2e-03	5.55	2.79e-08	0.83	FALSE
Brain	Marchf10	intron excision ratio	chr10_90833054_90835012	0.1	48	0.07	1.5e-07	-5.21	1.86e-07	0.88	FALSE
Brain	Marchf10	intron excision ratio	chr10_90833054_90836248	0.15	48	0.14	1.3e-12	5.4	6.69e-08	0.89	FALSE
Brain	Marchf10	intron excision ratio	chr10_90974697_91027769	0.04	1	0.03	1.6e-03	5.56	2.69e-08	0.36	FALSE
IC	Marchf10	alternative polyA	XM_039086143.2	0.5	252	0.39	2.3e-17	-5.41	6.26e-08	0.95	TRUE
IC	Kcnh6	gene expression	Kcnh6	0.12	11	0.05	2.9e-03	-5.6	2.18e-08	0.8	FALSE
IC	Marchf10	gene expression	Marchf10	0.29	222	0.25	5.8e-11	-5.74	9.49e-09	0.95	FALSE
IC	Marchf10	intron excision ratio	chr10_90833054_90835012	0.22	1	0.14	1.3e-06	-5.56	2.69e-08	0.86	TRUE
IC	Marchf10	intron excision ratio	chr10_90833054_90836248	0.31	1	0.27	1.5e-11	5.56	2.67e-08	0.95	FALSE
IL	Marchf10	alternative polyA	XM_039086143.2	0.27	1	0.17	6.2e-05	-5.56	2.69e-08	0.38	FALSE
Liver	Cyb561	alternative TSS	XM_039086163.2	0.11	1	0.05	1.1e-06	-5.51	3.60e-08	0.99	FALSE
Liver	Cyb561	intron excision ratio	chr10_91382013_91388418	0.16	1	0.08	4.7e-09	-5.51	3.60e-08	0.99	FALSE
NAcc	Marchf10	alternative polyA	XM_039086143.2	0.02	1	0.02	1.7e-03	-5.56	2.67e-08	0.28	FALSE
NAcc	Marchf10	alternative polyA	XM_063269194.1	0.02	1	0.01	1.8e-03	5.56	2.67e-08	0.24	FALSE
NAcc	Marchf10	alternative polyA	XM_039086143.2	0.13	1	0.12	1.5e-17	-5.56	2.69e-08	0.95	FALSE
NAcc	Marchf10	intron excision ratio	chr10_90833054_90835012	0.07	2	0.06	3.9e-09	-5.45	4.92e-08	0.95	FALSE
NAcc	Marchf10	intron excision ratio	chr10_90833054_90836248	0.09	1	0.09	4.1e-13	5.56	2.69e-08	0.95	FALSE
OFC	Marchf10	alternative polyA	XM_039086143.2	0.44	1	0.22	6.7e-06	-5.56	2.69e-08	0.4	FALSE
PL	Marchf10	alternative polyA	XM_039086143.2	0.06	1	0.04	1.7e-05	-5.56	2.69e-08	0.93	FALSE
PL	Marchf10	alternative polyA	XM_063269194.1	0.06	1	0.05	8.8e-06	5.56	2.69e-08	0.94	FALSE
PL	Marchf10	alternative polyA	XM_039086143.2	0.31	1	0.27	2.3e-29	-5.56	2.69e-08	0.95	FALSE
PL	Marchf10	alternative polyA	XM_063269194.1	0.08	1	0.06	6.1e-07	5.56	2.69e-08	0.95	FALSE
PL	Marchf10	gene expression	Marchf10	0.19	1	0.15	1.5e-16	-5.54	2.97e-08	0.95	FALSE
PL	Marchf10	isoform ratio	XM_017597338.3	0.13	28	0.14	8.7e-15	-5.7	1.21e-08	0.93	TRUE
PL	Marchf10	intron excision ratio	chr10_90833054_90835012	0.07	1	0.07	5.5e-08	-5.56	2.67e-08	0.95	FALSE
PL	Marchf10	intron excision ratio	chr10_90833054_90836248	0.11	1	0.12	1.1e-12	5.56	2.67e-08	0.95	FALSE
pVTA	Marchf10	alternative polyA	XM_039086143.2	0.21	1	0.16	1.4e-12	-5.56	2.69e-08	0.95	FALSE
pVTA	Marchf10	gene expression	Marchf10	0.07	1	0.03	9.1e-04	-5.56	2.69e-08	0.85	FALSE