Hub : Traits : Bone: cortical porosity : ←

chr10:88,340,994-91,822,036

Trait: Bone: cortical porosity

Best TWAS P=8.97e-09 · Best GWAS P=8.33e-09 conditioned to 2.41e-02

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
BLA	Mrc2	gene expression	ENSRNOG00000006548	0.07	1	0.03	1.3e-02	5.74	9.45e-09	0.11	FALSE
BLA	Marchf10	intron excision ratio	chr10:90333190:90335149	0.13	1	0.08	5.1e-05	-5.74	9.45e-09	0.57	FALSE
BLA	Marchf10	intron excision ratio	chr10:90333190:90336385	0.22	1	0.1	4.6e-06	5.74	9.45e-09	0.86	FALSE
Brain	Marchf10	alternative polyA	ENSRNOT00000009316	0.06	2472	0.04	1.0e-04	-5.11	3.21e-07	0.9	FALSE
Brain	Crhr1	gene expression	ENSRNOG00000004900	0.14	2613	0.03	1.2e-03	-5.1	3.40e-07	0.24	FALSE
Brain	Kcnh6	gene expression	ENSRNOG00000008078	0.05	1981	0.03	2.2e-03	-5.22	1.74e-07	0.49	FALSE
Brain	Marchf10	intron excision ratio	chr10:90333190:90335149	0.1	9	0.08	4.2e-08	-5.39	7.15e-08	0.89	FALSE
Brain	Marchf10	intron excision ratio	chr10:90333190:90336385	0.17	11	0.12	1.5e-11	5.66	1.49e-08	0.94	FALSE
Brain	Strada	intron excision ratio	chr10:91104254:91111276	0.05	1	0.02	2.3e-03	5.7	1.21e-08	0.84	FALSE
Liver	Cyb561	intron excision ratio	chr10:90882199:90888604	0.16	15	0.08	6.2e-09	-5.73	1.03e-08	0.99	FALSE
NAcc	Mrc2	gene expression	ENSRNOG00000006548	0.15	126	0.09	6.3e-07	5.37	7.93e-08	0.43	FALSE
PL	Marchf10	gene expression	ENSRNOG00000007084	0.14	1	0.11	6.1e-09	-5.75	8.97e-09	0.96	TRUE
PL	Marchf10	intron excision ratio	chr10:90333190:90335149	0.06	13	0.04	8.1e-04	-5.58	2.35e-08	0.81	FALSE
PL	Marchf10	intron excision ratio	chr10:90333190:90336385	0.12	1	0.13	4.5e-10	5.75	8.97e-09	0.96	FALSE