Best TWAS P=8.058128e-09 · Best GWAS P=9.105026e-11 conditioned to 0.00218373
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | PL | Trps1 | isoform ratio | ENSRNOT00000050774 | 0.04 | 0 | blup | 1997 | 0.02 | 0.01 | -5.6 | 5.8 | 8.1e-09 | -0.82 | 0.47 | 0.28 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.