Best TWAS P=4.148018e-08 · Best GWAS P=1.006466e-06 conditioned to 0.08704844
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Eye | Tafa5 | gene expression | ENSRNOG00000049349 | 0.7 | 0.15 | lasso | 15 | 0.24 | 0.00014 | 3.5 | -5.5 | 4.1e-08 | 0.66 | 0.48 | 0.19 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.