Best TWAS P = 1.52e-08 · Best GWAS P= 8.33e-09 conditioned to 1.00e+00
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLA | Dnai7 | isoform ratio | NM_001106627.3 | 0.06 | 1 | 0.06 | 5.0e-04 | -5.24 | 1.63e-07 | 0.07 | FALSE |
| Brain | Irag2 | alternative TSS | NM_001427185.1 | 0.03 | 1 | 0.03 | 1.7e-03 | 5.43 | 5.60e-08 | 0.12 | FALSE |
| Brain | Sspn | alternative TSS | NM_001109255.2 | 0.09 | 368 | 0.11 | 1.2e-10 | 5.66 | 1.52e-08 | 0.5 | TRUE |
| Brain | Sspn | alternative TSS | XM_017592843.3 | 0.07 | 383 | 0.09 | 5.9e-09 | -5.58 | 2.38e-08 | 0.49 | FALSE |
| NAcc | Bcat1 | isoform ratio | NM_017253.3 | 0.13 | 1 | 0.13 | 1.4e-19 | -5.25 | 1.54e-07 | 0.46 | TRUE |
| OFC | Bcat1 | alternative TSS | NM_017253.3 | 0.23 | 1 | 0.13 | 5.2e-04 | 5.26 | 1.45e-07 | 0.06 | FALSE |
| OFC | Irag2 | gene expression | Irag2 | 0.53 | 12 | 0.31 | 3.8e-08 | 5.29 | 1.24e-07 | 0.49 | FALSE |
| PL | Bcat1 | alternative TSS | NM_017253.3 | 0.13 | 25 | 0.14 | 1.2e-14 | 5.26 | 1.44e-07 | 0.61 | TRUE |
| PL | Bcat1 | gene expression | Bcat1 | 0.02 | 1 | 0.01 | 1.2e-02 | 5.25 | 1.48e-07 | 0.05 | FALSE |
| PL | Bcat1 | isoform ratio | NM_017253.3 | 0.13 | 21 | 0.14 | 5.5e-15 | 5.29 | 1.23e-07 | 0.6 | FALSE |