Best TWAS P=4.36e-08 · Best GWAS P=8.09e-08 conditioned to 1.00e+00
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Adipose | Mccc1 | gene expression | Mccc1 | 0.53 | 228 | 0.33 | 4.5e-38 | -5.48 | 4.36e-08 | 0.56 | TRUE |
| Brain | Mccc1 | isoform ratio | XM_039101989.1 | 0.04 | 2263 | 0.02 | 2.6e-03 | 5.21 | 1.92e-07 | 0.49 | TRUE |
| PL | Atp11b | alternative TSS | XM_039103613.1 | 0.04 | 1834 | 0.02 | 3.9e-03 | -5.21 | 1.84e-07 | 0.59 | FALSE |
| PL | Atp11b | alternative TSS | XM_039103616.1 | 0.04 | 1 | 0.02 | 6.6e-03 | -5.25 | 1.50e-07 | 0.05 | FALSE |
| PL | Atp11b | isoform ratio | XM_039103612.1 | 0.05 | 1 | 0.02 | 9.3e-04 | 5.35 | 8.75e-08 | 0.24 | FALSE |
| PL | Atp11b | isoform ratio | XM_039103616.1 | 0.05 | 1 | 0.03 | 1.7e-04 | -5.35 | 8.75e-08 | 0.32 | FALSE |
| PL | Mccc1 | isoform ratio | XR_005500259.1 | 0.1 | 25 | 0.08 | 5.2e-09 | -5.31 | 1.07e-07 | 0.6 | FALSE |
| pVTA | Zfp267 | mRNA stability | Zfp267 | 0.67 | 11 | 0.46 | 6.5e-22 | -5.22 | 1.81e-07 | 0 | TRUE |