Hub : Traits : BMI with tail : ← : →

chr1:179,074,573-180,882,886

Trait: BMI with tail

Best TWAS P = 4.09e-10 · Best GWAS P= 3.34e-10 conditioned to 1.10e-01

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Sox6	alternative TSS	XM_039106343.2	0.02	1	0.01	1.3e-02	6.02	1.76e-09	0.03	FALSE
Adipose	Plekha7	gene expression	Plekha7	0.34	1041	0.06	8.0e-07	5.68	1.38e-08	0.42	FALSE
Adipose	Sox6	gene expression	Sox6	0.04	1	0.03	6.0e-04	-6.01	1.86e-09	0.04	FALSE
Adipose	Sox6	isoform ratio	XM_039106343.2	0.02	881	0.01	1.2e-02	6.05	1.48e-09	0.29	FALSE
Adipose	C1h11orf58	mRNA stability	C1h11orf58	0.47	46	0.1	5.0e-11	6.02	1.75e-09	0.53	FALSE
Adipose	Pik3c2a	mRNA stability	Pik3c2a	0.08	1	0.05	1.4e-06	5.98	2.18e-09	0.4	FALSE
Adipose	Sox6	mRNA stability	Sox6	0.05	881	0.02	6.1e-03	-6.04	1.55e-09	0.46	FALSE
BLA	Plekha7	alternative polyA	XM_063279483.1	0.09	1041	0.06	6.2e-04	-6.04	1.55e-09	0.5	FALSE
BLA	Plekha7	alternative polyA	XM_063279498.1	0.06	1	0.04	6.0e-03	5.92	3.24e-09	0.04	FALSE
BLA	Plekha7	alternative polyA	XM_063279498.1	0.05	1	0.03	1.7e-02	5.92	3.24e-09	0.04	FALSE
BLA	Plekha7	alternative TSS	XM_063279498.1	0.06	1	0.01	5.0e-02	-5.8	6.55e-09	0.04	FALSE
BLA	Plekha7	gene expression	Plekha7	0.12	1041	0.08	3.9e-05	-6.04	1.54e-09	0.51	FALSE
BLA	Plekha7	isoform ratio	XM_039101147.2	0.07	1041	0.04	2.9e-03	6.03	1.69e-09	0.4	FALSE
Brain	Plekha7	alternative TSS	XM_063279498.1	0.03	1	0.01	3.5e-02	-5.93	3.01e-09	0.03	FALSE
Brain	Plekha7	alternative TSS	XM_039101147.2	0.03	1041	0.02	7.5e-03	6.04	1.57e-09	0.38	FALSE
Brain	Plekha7	alternative TSS	XM_063279498.1	0.03	1	0.01	1.6e-02	-5.99	2.13e-09	0.03	FALSE
Brain	C1h11orf58	gene expression	C1h11orf58	0.07	882	0.05	1.9e-05	6.05	1.47e-09	0.53	FALSE
Brain	LOC120099912	gene expression	LOC120099912	0.14	1	0.13	6.8e-12	-5.99	2.13e-09	0.47	FALSE
Brain	Plekha7	gene expression	Plekha7	0.18	1	0.15	1.2e-13	-6.04	1.51e-09	0.55	FALSE
Brain	Rps13	gene expression	Rps13	0.03	1055	0.03	1.6e-03	-6.04	1.55e-09	0.44	FALSE
Eye	Plekha7	isoform ratio	XM_039101152.2	0.43	1041	0.05	6.9e-02	6.04	1.51e-09	0.22	FALSE
IC	LOC120099912	gene expression	LOC120099912	0.08	1037	0.04	6.5e-03	-6.05	1.47e-09	0.34	FALSE
IC	Plekha7	gene expression	Plekha7	0.08	1041	0.02	4.0e-02	-6.05	1.43e-09	0.33	FALSE
IL	Rps13	gene expression	Rps13	0.16	1	0.07	7.7e-03	-5.37	7.72e-08	0.05	FALSE
LHb	Sox6	alternative TSS	XM_063285275.1	0.21	1	0.11	1.7e-03	-6.09	1.15e-09	0.06	FALSE
Liver	Pik3c2a	gene expression	Pik3c2a	0.02	1151	0.01	1.6e-02	6.01	1.91e-09	0.25	FALSE
Liver	Rps13	gene expression	Rps13	0.04	1055	0.02	4.3e-03	-6.03	1.60e-09	0.4	FALSE
Liver	Nucb2	isoform ratio	NM_021663.2	0.04	1148	0.01	8.0e-03	5.95	2.63e-09	0.33	FALSE
Liver	Nucb2	isoform ratio	XM_006230095.5	0.03	1148	0.01	2.5e-02	-5.96	2.51e-09	0.26	FALSE
Liver	Nucb2	intron excision ratio	chr1_180185261_180203629	0.03	12	0.01	2.4e-02	-6.03	1.62e-09	0.32	FALSE
Liver	Nucb2	intron excision ratio	chr1_180190391_180203629	0.06	1	0.01	9.7e-03	6.05	1.44e-09	0.03	FALSE
Liver	Sox6	intron excision ratio	chr1_179377361_179444989	0.18	1	0.02	5.7e-03	6.01	1.86e-09	0.03	FALSE
Liver	Nucb2	mRNA stability	Nucb2	0.16	26	0.08	4.5e-09	5.55	2.82e-08	0.44	FALSE
NAcc	Plekha7	alternative TSS	XM_039101147.2	0.01	2	0.01	3.2e-03	6.25	4.09e-10	0.37	TRUE
NAcc	Plekha7	alternative TSS	XM_063279498.1	0.02	1	0.02	8.3e-04	-5.37	7.72e-08	0.03	FALSE
NAcc	C1h11orf58	gene expression	C1h11orf58	0.05	882	0.04	3.8e-07	6.04	1.52e-09	0.53	FALSE
NAcc	LOC120099912	gene expression	LOC120099912	0.06	1037	0.06	1.0e-08	-6.06	1.36e-09	0.51	FALSE
NAcc	Nucb2	gene expression	Nucb2	0.02	1148	0.01	3.8e-02	5.97	2.40e-09	0.34	FALSE
NAcc	Pik3c2a	gene expression	Pik3c2a	0.02	1	0.02	6.4e-04	6.08	1.24e-09	0.04	FALSE
NAcc	Plekha7	gene expression	Plekha7	0.03	1041	0.03	5.8e-05	-6.06	1.37e-09	0.5	FALSE
NAcc	Nucb2	mRNA stability	Nucb2	0.03	1	0.02	5.8e-04	5.8	6.55e-09	0.03	FALSE
NAcc	Sox6	mRNA stability	Sox6	0.03	881	0.02	2.3e-04	-6.04	1.56e-09	0.52	FALSE
OFC	Plekha7	gene expression	Plekha7	0.38	136	0.13	6.1e-04	-6.2	5.58e-10	0.43	FALSE
PL	Plekha7	gene expression	Plekha7	0.03	1041	0.02	1.2e-03	-6.04	1.54e-09	0.47	FALSE
PL	Sox6	mRNA stability	Sox6	0.04	881	0.03	1.1e-04	-6.04	1.52e-09	0.52	FALSE
pVTA	C1h11orf58	gene expression	C1h11orf58	0.04	882	0.02	8.0e-03	6.04	1.50e-09	0.45	FALSE
pVTA	LOC120099912	gene expression	LOC120099912	0.11	1037	0.11	3.8e-09	-6.05	1.43e-09	0.52	FALSE
pVTA	Plekha7	gene expression	Plekha7	0.17	1041	0.18	1.2e-14	-6.04	1.53e-09	0.52	FALSE
pVTA	Rps13	gene expression	Rps13	0.03	1055	0.01	3.0e-02	-6.04	1.56e-09	0.36	FALSE
pVTA	Plekha7	isoform ratio	XM_063279492.1	0.04	1041	0.02	1.1e-02	-6.04	1.51e-09	0.42	FALSE
pVTA	Plekha7	intron excision ratio	chr1_179800164_179803798	0.05	1041	0.04	6.2e-04	-6.05	1.45e-09	0.48	FALSE
pVTA	Plekha7	intron excision ratio	chr1_179833716_179836198	0.05	1041	0.02	4.5e-03	-6.02	1.74e-09	0.42	FALSE