Hub : Traits : BMI with tail : ← →

chr9:65,337,960-67,262,437

Trait: BMI with tail

Best TWAS P=1.265967e-08 · Best GWAS P=3.333926e-08 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	BLA	Mettl21a	gene expression	ENSRNOG00000014212	0.07	0.04	enet	1295	0.04	2.1e-03	5.0	5.1	3.2e-07	0.99	0.50	0.39	FALSE
2	BLA	Plekhm3	gene expression	ENSRNOG00000023760	0.05	0.00	blup	1335	0.01	4.9e-02	5.0	5.4	5.7e-08	0.99	0.48	0.42	FALSE
3	BLA	Cryga	intron excision ratio	chr9:66486750:66490303	0.16	0.17	blup	1325	0.17	2.7e-09	4.9	-5.1	3.5e-07	-0.98	0.50	0.50	FALSE
4	Brain	Cryga	alternative TSS	ENSRNOT00000019963	0.04	0.04	lasso	27	0.05	1.2e-05	5.5	5.4	5.9e-08	1.00	0.45	0.54	FALSE
5	Brain	Cryga	alternative TSS	ENSRNOT00000072983	0.04	0.04	lasso	25	0.05	1.5e-05	5.5	-5.4	5.6e-08	-1.00	0.45	0.54	FALSE
6	Brain	Mettl21a	gene expression	ENSRNOG00000014212	0.05	0.04	enet	329	0.04	2.0e-04	5.5	5.6	2.7e-08	0.98	0.49	0.48	FALSE
7	Brain	Idh1	gene expression	ENSRNOG00000015020	0.02	0.02	top1	1	0.02	4.1e-03	5.3	5.3	1.1e-07	0.98	0.06	0.04	FALSE
8	Brain	Pikfyve	gene expression	ENSRNOG00000015158	0.05	0.06	enet	61	0.06	2.3e-06	5.5	-5.5	4.5e-08	-0.98	0.46	0.54	FALSE
9	Brain	Cryga	intron excision ratio	chr9:66486750:66490303	0.16	0.13	lasso	33	0.16	2.8e-14	5.3	-5.2	2.1e-07	-0.98	0.50	0.50	FALSE
10	IL	Fzd5	gene expression	ENSRNOG00000014678	0.17	0.07	top1	1	0.07	1.0e-02	5.5	-5.5	4.1e-08	-1.00	0.07	0.06	FALSE
11	LHb	Mettl21a	gene expression	ENSRNOG00000014212	0.16	0.11	lasso	3	0.13	5.5e-04	5.1	5.3	1.1e-07	0.99	0.57	0.26	FALSE
12	Liver	Mettl21a	gene expression	ENSRNOG00000014212	0.06	0.03	enet	135	0.04	4.5e-05	5.0	5.1	3.4e-07	0.99	0.56	0.44	FALSE
13	Liver	Fzd5	gene expression	ENSRNOG00000014678	0.05	0.02	blup	1271	0.03	1.1e-04	5.3	5.3	1.2e-07	1.00	0.55	0.44	FALSE
14	Liver	Idh1	isoform ratio	ENSRNOT00000020322	0.03	0.00	blup	1626	0.00	9.8e-02	4.9	-5.6	2.1e-08	-0.95	0.40	0.36	FALSE
15	Liver	Idh1	isoform ratio	ENSRNOT00000108404	0.03	0.00	blup	1626	0.01	6.4e-02	4.9	5.6	1.9e-08	0.96	0.41	0.39	FALSE
16	NAcc	Fzd5	gene expression	ENSRNOG00000014678	0.09	0.02	enet	557	0.04	1.1e-03	5.5	-5.7	1.3e-08	-0.94	0.40	0.52	TRUE
17	OFC	Mettl21a	gene expression	ENSRNOG00000014212	0.13	0.09	top1	1	0.09	4.1e-03	5.1	5.1	3.1e-07	0.99	0.07	0.05	FALSE
18	PL	Fzd5	gene expression	ENSRNOG00000014678	0.08	0.05	blup	1270	0.08	2.2e-06	5.5	-5.3	1.1e-07	-1.00	0.54	0.45	FALSE
19	PL	Cryga	gene expression	ENSRNOG00000046343	0.12	0.05	blup	1324	0.08	1.1e-06	4.9	-5.2	2.1e-07	-0.98	0.50	0.50	FALSE
20	PL	Cryga	intron excision ratio	chr9:66486750:66490303	0.09	0.10	blup	1324	0.12	2.6e-09	5.5	-5.4	7.4e-08	-0.99	0.48	0.52	FALSE
21	PL	Idh1	mRNA stability	ENSRNOG00000015020	0.03	0.01	top1	1	0.01	5.1e-02	5.3	-5.3	1.0e-07	-0.99	0.06	0.04	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.