Best TWAS P=2.207398e-07 · Best GWAS P=7.028301e-07 conditioned to 3.06553e-20
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | IL | Fam81a | gene expression | ENSRNOG00000057501 | 0.29 | 0.19 | enet | 6 | 0.26 | 5.5e-07 | 4.9 | -5.2 | 2.2e-07 | 0.54 | 0.48 | 0.5 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.