chr8:72,966,755-74,474,378

Trait: BMI with tail

Best TWAS P=1.92e-08 · Best GWAS P=2.29e-07 conditioned to 4.45e-01

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose Ccpg1 alternative polyA XM_006243332.4 0.02 1365 0.01 1.6e-02 5.46 4.81e-08 0.53 FALSE
Adipose Ccpg1 alternative polyA XM_008766318.3 0.02 1365 0.01 1.4e-02 -5.46 4.77e-08 0.54 FALSE
Adipose Pigb gene expression Pigb 0.07 47 0.06 5.0e-07 5.36 8.40e-08 0.58 FALSE
Adipose Pygo1 gene expression Pygo1 0.02 1311 0.02 3.1e-03 -5.62 1.92e-08 0.47 TRUE
Brain Dnaaf4 intron excision ratio chr8_73700709_73703207 0.02 1358 0.01 2.0e-02 -5.29 1.22e-07 0.38 FALSE
Brain Pygo1 intron excision ratio chr8_73700709_73703207 0.02 1352 0.01 2.0e-02 -5.3 1.18e-07 0.39 FALSE
Liver Ccpg1 mRNA stability Ccpg1 0.07 109 0.08 1.5e-09 5.34 9.39e-08 0.62 FALSE
NAcc Ccpg1 isoform ratio NM_001401188.1 0.11 1406 0.12 1.0e-13 -5.21 1.91e-07 0.38 FALSE
RMTg Dnaaf4 intron excision ratio chr8_73699187_73700484 0.11 1358 0.04 4.2e-02 5.49 3.99e-08 0.41 FALSE