Best TWAS P=1.355656e-07 · Best GWAS P=7.846133e-06 conditioned to 0.9234093
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | PL | Rpap3 | gene expression | ENSRNOG00000053405 | 0.42 | 0.31 | enet | 77 | 0.33 | 1.7e-25 | 4.5 | -5.3 | 1.4e-07 | -0.86 | 0.61 | 0.38 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.