Hub : Traits : dissection: UMAP 3 of all traits : ← →

chr1:71,391,635-74,334,045

Best TWAS P=1.228668e-08 · Best GWAS P=1.297308e-09 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Zscan18	gene expression	ENSRNOG00000026861	0.66	0.22	enet	364	0.28	2.3e-31	-5.2	-5.5	4.9e-08	0.88	0.24	0.76	FALSE
2	Adipose	Vom2r35	gene expression	ENSRNOG00000050831	0.46	0.18	enet	165	0.19	1.4e-20	-5.3	-5.4	6.4e-08	0.93	0.27	0.73	FALSE
3	Adipose	Zfp606	intron excision ratio	chr1:72985017:72995089	0.02	0.01	top1	1	0.01	2.1e-02	-5.3	-5.3	1.3e-07	0.94	0.04	0.04	FALSE
4	Adipose	AABR07002065.2	intron excision ratio	chr1:73603888:73605801	0.06	0.03	blup	716	0.03	3.3e-04	-5.2	-5.1	2.8e-07	0.93	0.24	0.72	FALSE
5	BLA	Zfp329	isoform ratio	ENSRNOT00000026204	0.31	-0.01	lasso	14	0.00	2.9e-01	-5.2	5.2	2.2e-07	-0.95	0.10	0.28	FALSE
6	Brain	NA	gene expression	ENSRNOG00000070456	0.06	0.06	blup	1714	0.08	1.5e-07	-5.2	5.2	1.6e-07	-0.96	0.61	0.39	FALSE
7	LHb	AABR07002065.2	alternative TSS	ENSRNOT00000107167	0.81	0.10	lasso	3	0.18	6.0e-05	-5.3	-5.2	1.8e-07	0.02	0.30	0.54	TRUE
8	Liver	AABR07002065.2	alternative TSS	ENSRNOT00000094704	0.09	0.02	top1	1	0.02	3.9e-03	-5.3	5.3	1.5e-07	-0.94	0.03	0.05	FALSE
9	Liver	AABR07002065.2	alternative TSS	ENSRNOT00000094704	0.07	0.01	top1	1	0.01	2.5e-02	-5.3	5.3	1.5e-07	-0.94	0.02	0.04	FALSE
10	Liver	Zscan18	gene expression	ENSRNOG00000026861	0.63	0.17	enet	165	0.23	2.4e-25	-5.2	-5.3	1.4e-07	0.76	0.23	0.77	TRUE
11	Liver	AABR07002065.2	isoform ratio	ENSRNOT00000100681	0.09	0.03	top1	1	0.03	1.3e-04	-5.3	-5.3	1.5e-07	0.93	0.12	0.56	FALSE
12	Liver	Zfp324	intron excision ratio	chr1:73602291:73602860	0.19	0.09	enet	311	0.10	1.5e-11	-5.3	5.1	2.7e-07	-0.91	0.22	0.78	FALSE
13	Liver	AABR07002065.2	intron excision ratio	chr1:73603888:73605801	0.11	0.05	enet	132	0.07	1.1e-08	-4.8	-5.3	1.4e-07	0.75	0.25	0.75	TRUE
14	NAcc	Zbtb45	gene expression	ENSRNOG00000027459	0.17	0.23	top1	1	0.23	8.2e-06	-5.2	-5.2	1.9e-07	0.92	0.05	0.13	FALSE
15	NAcc2	AABR07002065.2	alternative polyA	ENSRNOT00000094704	0.22	0.05	lasso	26	0.05	1.5e-03	-4.7	-5.3	1.5e-07	0.86	0.24	0.31	FALSE
16	NAcc2	AABR07002065.2	alternative polyA	ENSRNOT00000026540	0.15	0.04	top1	1	0.04	5.1e-03	-5.2	5.2	1.6e-07	-0.93	0.03	0.05	FALSE
17	NAcc2	Zbtb45	gene expression	ENSRNOG00000027459	0.15	0.08	top1	1	0.09	2.5e-05	-5.2	-5.2	2.2e-07	0.92	0.14	0.52	FALSE
18	NAcc2	NA	gene expression	ENSRNOG00000031178	0.21	0.07	top1	1	0.07	1.9e-04	-5.7	5.7	1.3e-08	-0.96	0.10	0.42	FALSE
19	NAcc2	Zfp128	gene expression	ENSRNOG00000031459	0.05	0.03	top1	1	0.03	1.2e-02	-5.2	5.2	2.2e-07	-0.93	0.03	0.05	FALSE
20	NAcc2	NA	gene expression	ENSRNOG00000070456	0.08	0.00	enet	346	0.01	1.4e-01	-5.6	5.4	7.9e-08	-0.89	0.30	0.33	FALSE
21	PL	Zfp551	intron excision ratio	chr1:72548538:72553107	0.14	0.06	top1	1	0.06	1.8e-02	-5.7	5.7	1.2e-08	-0.96	0.09	0.06	TRUE
22	PL2	NA	gene expression	ENSRNOG00000070456	0.05	0.04	top1	1	0.04	5.0e-03	-5.3	5.3	1.3e-07	-0.96	0.07	0.04	FALSE
23	PL2	Zbtb45	intron excision ratio	chr1:73638091:73639378	0.05	0.02	enet	14	0.02	3.1e-02	-5.2	-5.1	2.6e-07	0.95	0.20	0.50	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.