Best TWAS P=2.698264e-11 · Best GWAS P=0.001636117 conditioned to 0.004667964
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | PL | Apeh | mRNA stability | ENSRNOG00000029572 | 0.18 | 0.03 | enet | 335 | 0.04 | 0.00042 | 2.1 | -6.7 | 2.7e-11 | -0.75 | 0.15 | 0.1 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.