Best TWAS P=3.520346e-07 · Best GWAS P=0.01340892 conditioned to 0.02950831
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Brain | Plekho2 | mRNA stability | ENSRNOG00000029242 | 0.33 | 0.04 | blup | 596 | 0.06 | 1.5e-06 | 2 | 5.1 | 3.5e-07 | 0.76 | 0.06 | 0.21 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.