Hub : Traits : Reaction time num false alarms : ← →

chr10:10,636,724-12,342,417

Trait: Reaction time num false alarms

Best TWAS P=2.461536e-08 · Best GWAS P=2.580669e-07 conditioned to 0.9380359

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Nlrc3	alternative TSS	ENSRNOT00000115404	0.06	0.02	blup	1768	0.02	1.5e-03	-4.7	-5.2	2.6e-07	0.88	0.33	0.66	FALSE
2	Adipose	Slx4	mRNA stability	ENSRNOG00000024445	0.36	0.36	blup	1649	0.37	2.3e-43	-4.6	5.3	9.7e-08	-0.89	0.47	0.53	FALSE
3	Brain	Crebbp	gene expression	ENSRNOG00000005330	0.28	0.25	lasso	14	0.28	2.8e-26	-5.2	5.1	2.7e-07	-0.98	0.18	0.82	FALSE
4	Liver	Cluap1	intron excision ratio	chr10:11612608:11613603	0.03	0.01	blup	2103	0.01	1.5e-02	-4.7	-5.2	2.5e-07	0.82	0.32	0.40	FALSE
5	Liver	Naa60	intron excision ratio	chr10:11612608:11613603	0.03	0.01	blup	2151	0.01	1.5e-02	-4.7	-5.2	2.5e-07	0.82	0.33	0.40	FALSE
6	NAcc	Nlrc3	alternative TSS	ENSRNOT00000115404	0.04	0.02	blup	1765	0.02	7.4e-03	-4.9	-5.1	3.0e-07	0.89	0.21	0.71	FALSE
7	PL	Slx4	mRNA stability	ENSRNOG00000024445	0.18	0.15	blup	1646	0.15	1.2e-11	-4.7	5.6	2.5e-08	-0.92	0.21	0.79	TRUE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.