Best TWAS P=3.006463e-07 · Best GWAS P=1.345688e-08 conditioned to 0.001687809
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | OFC | Rasgrp3 | mRNA stability | ENSRNOG00000032703 | 0.26 | 0.15 | top1 | 1 | 0.15 | 0.00017 | 5.1 | -5.1 | 3e-07 | -0.64 | 0.12 | 0.06 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.