Best TWAS P=1.787003e-07 · Best GWAS P=1.228653e-06 conditioned to 0.3005981
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Liver | Tank | intron excision ratio | chr3:46164939:46179789 | 0.04 | 0.02 | blup | 1439 | 0.02 | 0.0027 | 4.2 | -5.2 | 1.8e-07 | -0.81 | 0.34 | 0.56 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.