Best TWAS P=1.046961e-16 · Best GWAS P=0.04031956 conditioned to 0.473566
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Vom2r35 | alternative polyA | ENSRNOT00000107882 | 0.27 | 0.05 | blup | 1024 | 0.07 | 5.4e-08 | -0.84 | 6.0 | 1.9e-09 | 0.06 | 0.06 | 0.03 | TRUE |
| 2 | Adipose | Zfp110 | gene expression | ENSRNOG00000031328 | 0.18 | 0.00 | blup | 738 | 0.03 | 1.4e-04 | -1.00 | -6.0 | 1.6e-09 | 0.22 | 0.01 | 0.01 | TRUE |
| 3 | BLA | Zfp110 | gene expression | ENSRNOG00000031328 | 0.47 | 0.01 | enet | 412 | 0.07 | 1.4e-04 | -0.88 | -6.9 | 7.1e-12 | 0.07 | 0.00 | 0.00 | FALSE |
| 4 | BLA | Zfp329 | isoform ratio | ENSRNOT00000118816 | 0.30 | -0.01 | enet | 401 | 0.02 | 2.7e-02 | -0.96 | -5.9 | 3.6e-09 | -0.06 | 0.01 | 0.00 | FALSE |
| 5 | Brain | Zscan18 | gene expression | ENSRNOG00000026861 | 0.42 | 0.01 | blup | 978 | 0.03 | 4.8e-04 | -0.88 | -7.6 | 4.1e-14 | 0.02 | 0.01 | 0.01 | TRUE |
| 6 | Brain | Zfp329 | isoform ratio | ENSRNOT00000026204 | 0.19 | 0.03 | enet | 176 | 0.04 | 1.0e-04 | 1.89 | 8.0 | 1.1e-15 | 0.17 | 0.04 | 0.06 | FALSE |
| 7 | Brain | Zfp329 | isoform ratio | ENSRNOT00000118816 | 0.20 | 0.03 | enet | 124 | 0.04 | 9.3e-05 | 1.89 | -8.3 | 1.0e-16 | -0.16 | 0.04 | 0.06 | TRUE |
| 8 | PL2 | Zfp329 | isoform ratio | ENSRNOT00000026204 | 0.46 | 0.00 | enet | 370 | 0.09 | 1.2e-05 | -0.88 | 7.5 | 4.4e-14 | 0.03 | 0.00 | 0.00 | FALSE |
| 9 | PL2 | Zfp329 | isoform ratio | ENSRNOT00000118816 | 0.47 | 0.00 | enet | 348 | 0.10 | 6.3e-06 | -0.88 | -7.1 | 1.0e-12 | -0.08 | 0.00 | 0.00 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.