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chr1:71,854,301-74,100,561

Trait: Food seeking constrained by brief footshock

Best TWAS P=1.046961e-16 · Best GWAS P=0.0002129893 conditioned to 3.101017e-14

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Vom2r35	alternative polyA	ENSRNOT00000107882	0.27	0.05	blup	1024	0.07	5.4e-08	-0.84	6.0	1.9e-09	-0.59	0.06	0.03	TRUE
2	Adipose	Zfp110	gene expression	ENSRNOG00000031328	0.18	0.00	blup	738	0.03	1.4e-04	-1.00	-6.0	1.6e-09	0.38	0.01	0.01	TRUE
3	BLA	Zfp110	gene expression	ENSRNOG00000031328	0.47	0.01	enet	412	0.07	1.4e-04	-0.88	-6.9	7.1e-12	0.46	0.00	0.00	FALSE
4	BLA	Zfp329	isoform ratio	ENSRNOT00000118816	0.30	-0.01	enet	401	0.02	2.7e-02	-0.96	-5.9	3.6e-09	0.59	0.01	0.00	FALSE
5	Brain	Zscan18	gene expression	ENSRNOG00000026861	0.42	0.01	blup	978	0.03	4.8e-04	-0.88	-7.6	4.1e-14	0.67	0.01	0.01	TRUE
6	Brain	Zfp329	isoform ratio	ENSRNOT00000026204	0.19	0.03	enet	176	0.04	1.0e-04	1.89	8.0	1.1e-15	-0.30	0.04	0.06	FALSE
7	Brain	Zfp329	isoform ratio	ENSRNOT00000118816	0.20	0.03	enet	124	0.04	9.3e-05	1.89	-8.3	1.0e-16	0.36	0.04	0.06	TRUE
8	PL	Zfp329	isoform ratio	ENSRNOT00000026204	0.43	0.00	blup	752	0.04	2.8e-04	1.90	7.7	1.7e-14	-0.56	0.00	0.00	FALSE
9	PL	Zfp329	isoform ratio	ENSRNOT00000118816	0.43	0.00	blup	752	0.04	2.7e-04	1.90	-7.7	1.5e-14	0.56	0.00	0.00	FALSE
10	PL	Vom1r50	intron excision ratio	chr1:72483651:72525014	0.18	0.00	blup	1711	0.01	7.0e-02	1.65	5.2	2.1e-07	-0.80	0.23	0.17	FALSE
11	PL	NA	intron excision ratio	chr1:72483651:72525014	0.18	0.00	blup	1711	0.01	7.0e-02	1.65	5.2	2.1e-07	-0.80	0.23	0.17	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.