Best TWAS P=3.566386e-08 · Best GWAS P=3.20852e-08 conditioned to 0.1209208
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | RGD1359108 | gene expression | ENSRNOG00000009478 | 0.13 | 0.06 | top1 | 1 | 0.06 | 1.9e-07 | 5.5 | -5.5 | 3.6e-08 | -0.86 | 0.11 | 0.87 | TRUE |
| 2 | NAcc2 | RGD1359108 | mRNA stability | ENSRNOG00000009478 | 0.13 | 0.05 | top1 | 1 | 0.05 | 8.9e-04 | 5.5 | 5.5 | 4.7e-08 | 0.98 | 0.05 | 0.10 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.