Best TWAS P = 7.13e-08 · Best GWAS P= 1.26e-09 conditioned to 2.15e-01
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Adipose | Wnt5a | gene expression | Wnt5a | 0.04 | 2489 | 0.02 | 1.4e-03 | 5.25 | 1.51e-07 | 0.65 | TRUE |
| Liver | Ccdc66 | mRNA stability | Ccdc66 | 0.07 | 1 | 0.01 | 1.0e-02 | -5.39 | 7.13e-08 | 0.08 | TRUE |
| NAcc | Erc2 | mRNA stability | Erc2 | 0.24 | 26 | 0.15 | 1.7e-22 | 5.27 | 1.38e-07 | 0.6 | FALSE |
| OFC | Erc2 | intron excision ratio | chr16_2825748_2855230 | 0.26 | 1 | 0.15 | 2.2e-04 | -5.35 | 8.80e-08 | 0.07 | FALSE |