Best TWAS P=3.138241e-07 · Best GWAS P=2.434131e-07 conditioned to 1
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Brain | Srek1ip1 | alternative TSS | ENSRNOT00000095129 | 0.03 | 0.03 | top1 | 1 | 0.03 | 0.00049 | 5.1 | 5.1 | 3.1e-07 | 0.97 | 0.05 | 0.10 | TRUE |
| 2 | NAcc2 | Trappc13 | gene expression | ENSRNOG00000012124 | 0.05 | 0.02 | top1 | 1 | 0.02 | 0.02800 | 5.1 | -5.1 | 3.1e-07 | -0.96 | 0.04 | 0.07 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.