Best TWAS P=6.306354e-08 · Best GWAS P=2.516756e-07 conditioned to 0.613248
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | PL | Ttc9 | alternative TSS | ENSRNOT00000009513 | 0.22 | 0.04 | enet | 25 | 0.14 | 0.00029 | -4.7 | 5.4 | 6.3e-08 | -0.92 | 0.23 | 0.6 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.