Best TWAS P=1.121138e-10 · Best GWAS P=2.089193e-11 conditioned to 1
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Adipose | Kit | mRNA stability | ENSRNOG00000002227 | 0.03 | 0.03 | enet | 416 | 0.05 | 4e-06 | -6.7 | -6.4 | 1.1e-10 | 0.96 | 0.06 | 0.92 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.