Best TWAS P=2.580452e-07 · Best GWAS P=0.06850963 conditioned to 0.8912089
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Adprhl1 | gene expression | ENSRNOG00000019504 | 0.43 | 0 | blup | 1550 | 0.04 | 1.1e-05 | -1.3 | 5.2 | 2.6e-07 | -0.33 | 0.01 | 0 | TRUE |
| 2 | Liver | Adprhl1 | gene expression | ENSRNOG00000019504 | 0.46 | 0 | blup | 1550 | 0.05 | 1.5e-06 | -1.5 | 5.1 | 3.2e-07 | -0.51 | 0.01 | 0 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.