Hub : Traits : Liver rubidium concentration : →

chr8:29,620,582-31,650,241

Best TWAS P=2.535723e-08 · Best GWAS P=1.391024e-08 conditioned to 0.1291457

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Arhgap32	alternative TSS	ENSRNOT00000011589	0.06	0.02	top1	1	0.01	7.2e-03	5.2	-5.2	1.8e-07	-0.91	0.06	0.04	FALSE
2	Adipose	Arhgap32	gene expression	ENSRNOG00000008709	0.07	0.05	enet	9	0.06	5.1e-07	4.6	-5.2	2.1e-07	-0.85	0.41	0.59	FALSE
3	Adipose	Arhgap32	isoform ratio	ENSRNOT00000099034	0.05	0.01	top1	1	0.01	3.0e-02	5.2	5.2	1.8e-07	0.91	0.05	0.03	FALSE
4	Adipose	Arhgap32	intron excision ratio	chr8:30624734:30658098	0.02	0.01	blup	1559	0.01	3.9e-02	5.0	5.2	2.4e-07	0.92	0.30	0.22	FALSE
5	BLA	Barx2	gene expression	ENSRNOG00000008592	0.22	0.14	top1	1	0.14	6.2e-08	5.6	5.6	2.5e-08	0.90	0.26	0.73	TRUE
6	BLA	Kcnj5	gene expression	ENSRNOG00000033796	0.11	0.06	enet	35	0.07	1.4e-04	5.1	-5.2	2.2e-07	-0.88	0.42	0.55	FALSE
7	BLA	Arhgap32	isoform ratio	ENSRNOT00000099034	0.06	0.05	top1	1	0.05	7.9e-04	5.2	5.2	1.8e-07	0.96	0.07	0.04	FALSE
8	BLA	Arhgap32	isoform ratio	ENSRNOT00000100925	0.06	0.06	top1	1	0.06	3.9e-04	5.2	-5.2	1.8e-07	-0.96	0.07	0.04	FALSE
9	Brain	Arhgap32	gene expression	ENSRNOG00000008709	0.25	0.25	top1	1	0.25	1.9e-23	5.3	5.3	1.1e-07	0.94	0.60	0.40	FALSE
10	Brain	Kcnj5	gene expression	ENSRNOG00000033796	0.03	0.04	top1	1	0.04	1.1e-04	5.4	-5.4	7.5e-08	-0.98	0.13	0.14	FALSE
11	Brain	Arhgap32	intron excision ratio	chr8:30624734:30658098	0.04	0.03	enet	14	0.03	4.2e-04	5.1	-5.3	9.4e-08	-0.92	0.56	0.41	FALSE
12	LHb	Barx2	gene expression	ENSRNOG00000008592	0.13	0.03	lasso	5	0.04	3.9e-02	5.1	5.3	9.2e-08	0.86	0.36	0.34	FALSE
13	Liver	Arhgap32	gene expression	ENSRNOG00000008709	0.03	0.01	top1	1	0.01	1.8e-02	5.2	5.2	1.9e-07	0.91	0.05	0.03	FALSE
14	Liver	Fli1	gene expression	ENSRNOG00000008904	0.06	0.05	top1	1	0.05	5.8e-06	5.5	5.5	3.4e-08	0.97	0.20	0.54	FALSE
15	NAcc	Barx2	gene expression	ENSRNOG00000008592	0.13	0.09	top1	1	0.09	5.4e-03	5.2	5.2	1.6e-07	0.96	0.07	0.05	FALSE
16	NAcc2	Arhgap32	gene expression	ENSRNOG00000008709	0.08	0.04	top1	1	0.04	3.2e-03	5.2	5.2	1.9e-07	0.93	0.06	0.04	FALSE
17	NAcc2	Kcnj5	gene expression	ENSRNOG00000033796	0.22	0.19	enet	47	0.19	2.2e-10	5.2	-5.4	6.4e-08	-0.99	0.40	0.60	FALSE
18	NAcc2	Arhgap32	isoform ratio	ENSRNOT00000099034	0.06	0.06	top1	1	0.06	2.8e-04	5.2	5.2	1.6e-07	0.95	0.09	0.05	FALSE
19	NAcc2	Arhgap32	isoform ratio	ENSRNOT00000100925	0.05	0.04	top1	1	0.04	3.0e-03	5.2	-5.2	1.8e-07	-0.96	0.07	0.04	FALSE
20	NAcc2	Arhgap32	intron excision ratio	chr8:30674889:30676047	0.05	0.03	blup	1564	0.03	5.9e-03	5.1	5.5	3.9e-08	0.97	0.50	0.37	FALSE
21	NAcc2	Arhgap32	intron excision ratio	chr8:30674889:30676050	0.05	0.03	blup	1564	0.03	6.9e-03	5.1	-5.5	3.5e-08	-0.97	0.48	0.37	FALSE
22	NAcc2	Kcnj5	mRNA stability	ENSRNOG00000033796	0.05	0.05	top1	1	0.05	1.2e-03	5.4	-5.4	7.5e-08	-0.94	0.07	0.05	FALSE
23	PL2	Kcnj5	gene expression	ENSRNOG00000033796	0.06	0.07	top1	1	0.07	1.6e-04	5.2	-5.2	1.9e-07	-0.97	0.11	0.07	FALSE
24	PL2	Arhgap32	intron excision ratio	chr8:30642932:30658098	0.06	0.03	top1	1	0.03	8.6e-03	5.1	5.1	2.8e-07	0.93	0.06	0.04	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.