Hub : Traits : Bone: maximum moment : ← →

chr9:87,238,851-88,946,694

Trait: Bone: maximum moment

Best TWAS P=5.398595e-08 · Best GWAS P=1.731198e-06 conditioned to 0.6542101

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Efhd1	mRNA stability	ENSRNOG00000015596	0.50	0.18	enet	190	0.20	2.7e-22	4.5	-5.3	1.5e-07	-0.55	0.06	0.94	FALSE
2	Brain	Neu2	gene expression	ENSRNOG00000016962	0.33	0.16	blup	1591	0.26	2.5e-24	4.7	5.2	2.3e-07	0.75	0.05	0.95	FALSE
3	LHb	Efhd1	mRNA stability	ENSRNOG00000015596	0.66	0.34	enet	11	0.39	3.0e-10	4.7	-5.1	2.7e-07	-0.83	0.06	0.94	FALSE
4	Liver	Efhd1	gene expression	ENSRNOG00000015596	0.37	0.14	blup	1594	0.20	8.5e-22	-3.7	-5.2	2.1e-07	-0.69	0.74	0.24	FALSE
5	OFC	Neu2	gene expression	ENSRNOG00000016962	0.61	0.20	blup	1585	0.21	1.0e-05	4.7	5.2	2.5e-07	0.89	0.07	0.92	FALSE
6	OFC	Efhd1	mRNA stability	ENSRNOG00000015596	0.64	0.18	blup	1586	0.20	1.6e-05	4.7	-5.4	5.4e-08	-0.91	0.07	0.90	TRUE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.