Hub : Traits : Bone: maximum force : ← : →

chr7:129,232,833-131,872,914

Trait: Bone: maximum force

Best TWAS P=3.03e-08 · Best GWAS P=1.34e-07 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Prpf40b	alternative polyA	XM_039079642.1	0.03	970	0.02	4.6e-03	-5.2	1.97e-07	0.4	FALSE
Adipose	Prpf40b	alternative polyA	XM_039079644.1	0.03	970	0.02	2.1e-03	5.21	1.91e-07	0.46	FALSE
Adipose	Spats2	alternative TSS	XM_039078933.1	0.03	1042	0.02	2.9e-03	-5.2	2.02e-07	0.42	FALSE
Adipose	Dnajc22	gene expression	Dnajc22	0.39	79	0.3	3.7e-34	-5.28	1.26e-07	0.49	FALSE
Adipose	Nckap5l	gene expression	Nckap5l	0.02	1	0.01	7.5e-02	5.22	1.79e-07	0.03	FALSE
Adipose	Prpf40b	gene expression	Prpf40b	0.19	970	0.17	6.1e-18	-5.28	1.31e-07	0.52	FALSE
Adipose	Prpf40b	isoform ratio	XM_039079644.1	0.02	970	0.02	6.0e-03	5.27	1.34e-07	0.36	FALSE
Adipose	Tmbim6	mRNA stability	Tmbim6	0.13	1026	0.11	8.7e-12	5.38	7.37e-08	0.5	FALSE
BLA	Faim2	gene expression	Faim2	0.15	988	0.15	1.6e-08	-5.37	7.84e-08	0.58	FALSE
BLA	Kcnh3	gene expression	Kcnh3	0.29	995	0.31	4.3e-17	-5.32	1.03e-07	0.52	FALSE
BLA	Mcrs1	gene expression	Mcrs1	0.05	1	0.04	3.7e-03	-5.42	5.85e-08	0.05	FALSE
BLA	Spats2	gene expression	Spats2	0.23	1043	0.22	3.3e-12	-5.27	1.38e-07	0.5	FALSE
BLA	Faim2	isoform ratio	XM_017594665.2	0.06	1	0.03	1.0e-02	-5.22	1.79e-07	0.05	FALSE
BLA	LOC102546778	mRNA stability	LOC102546778	0.09	1032	0.07	1.3e-04	5.36	8.15e-08	0.54	FALSE
Brain	Dnajc22	gene expression	Dnajc22	0.13	1045	0.18	1.8e-16	5.19	2.13e-07	0.49	FALSE
Brain	Faim2	gene expression	Faim2	0.51	68	0.57	9.2e-64	5.38	7.28e-08	0.59	FALSE
Brain	Kcnh3	gene expression	Kcnh3	0.56	995	0.69	1.3e-87	-5.21	1.89e-07	0.54	FALSE
Brain	LOC102546778	gene expression	LOC102546778	0.18	1032	0.23	2.1e-21	5.3	1.17e-07	0.56	FALSE
Brain	Nckap5l	gene expression	Nckap5l	0.07	1030	0.04	2.9e-04	5.35	8.56e-08	0.5	FALSE
Brain	Smarcd1	gene expression	Smarcd1	0.16	942	0.21	1.3e-19	5.27	1.34e-07	0.37	FALSE
Brain	Asic1	isoform ratio	XM_017595126.2	0.04	965	0.03	1.3e-03	5.23	1.70e-07	0.36	FALSE
Brain	Faim2	isoform ratio	NM_144756.2	0.08	988	0.08	1.0e-07	-5.26	1.47e-07	0.59	FALSE
Brain	LOC102546778	isoform ratio	XR_005487589.1	0.03	1032	0.03	1.9e-03	5.26	1.43e-07	0.5	FALSE
Brain	Kcnh3	intron excision ratio	chr7_130367391_130367495	0.03	995	0.03	3.9e-04	-5.28	1.29e-07	0.51	FALSE
Brain	LOC102546778	mRNA stability	LOC102546778	0.13	4	0.17	7.9e-16	5.54	3.03e-08	0.61	TRUE
Brain	Tmbim6	mRNA stability	Tmbim6	0.05	1027	0.06	2.3e-06	5.39	6.99e-08	0.54	FALSE
IL	LOC100362820	gene expression	LOC100362820	0.19	11	0.08	5.8e-03	-5.29	1.20e-07	0.34	FALSE
IL	Spats2	gene expression	Spats2	0.16	1	0.13	4.3e-04	5.35	8.83e-08	0.07	FALSE
LHb	Asic1	gene expression	Asic1	0.16	19	0.11	1.5e-03	-5.25	1.48e-07	0.44	FALSE
LHb	Faim2	gene expression	Faim2	0.59	988	0.44	6.6e-12	-5.37	7.68e-08	0.58	FALSE
LHb	Prph	gene expression	Prph	0.39	1	0.32	1.7e-08	-5.34	9.50e-08	0.64	FALSE
LHb	Spats2	gene expression	Spats2	0.26	1	0.25	1.2e-06	5.35	8.83e-08	0.29	FALSE
LHb	Tuba1b	gene expression	Tuba1b	0.66	1182	0.51	5.9e-14	5.18	2.18e-07	0.55	FALSE
LHb	Faim2	mRNA stability	Faim2	0.12	988	0.09	4.7e-03	-5.37	7.74e-08	0.36	FALSE
Liver	Asic1	gene expression	Asic1	0.21	965	0.2	2.4e-21	-5.25	1.53e-07	0.46	FALSE
Liver	C1ql4	gene expression	C1ql4	0.03	1	0.01	1.4e-02	5.22	1.79e-07	0.03	FALSE
Liver	Tmbim6	isoform ratio	NM_019381.2	0.1	1026	0.08	1.5e-09	-5.38	7.29e-08	0.5	FALSE
Liver	Tmbim6	isoform ratio	XM_006257323.4	0.09	1026	0.08	2.5e-09	5.39	6.97e-08	0.5	FALSE
Liver	Bcdin3d	mRNA stability	Bcdin3d	0.04	1036	0.03	2.1e-04	-5.4	6.72e-08	0.49	FALSE
Liver	LOC102546778	mRNA stability	LOC102546778	0.02	1031	0.01	7.0e-03	5.4	6.64e-08	0.37	FALSE
NAcc	Faim2	gene expression	Faim2	0.2	988	0.21	4.0e-24	-5.39	6.99e-08	0.58	FALSE
NAcc	Fmnl3	gene expression	Fmnl3	0.03	1	0.01	6.2e-03	5.22	1.82e-07	0.04	FALSE
NAcc	Kcnh3	gene expression	Kcnh3	0.04	24	0.04	3.1e-05	5.37	8.08e-08	0.53	FALSE
NAcc	LOC102546778	gene expression	LOC102546778	0.28	1032	0.16	1.1e-17	5.38	7.25e-08	0.5	FALSE
NAcc	Spats2	gene expression	Spats2	0.12	1	0.18	2.1e-20	5.35	8.83e-08	0.77	FALSE
NAcc	Prpf40b	intron excision ratio	chr7_130452523_130452696	0.01	971	0.02	5.2e-03	5.31	1.11e-07	0.4	FALSE
NAcc	Tuba1c	intron excision ratio	chr7_130118788_130164148	0.05	1075	0.05	1.6e-06	-5.18	2.26e-07	0.52	FALSE
NAcc	LOC102546778	mRNA stability	LOC102546778	0.07	1032	0.1	9.3e-12	5.3	1.13e-07	0.56	FALSE
NAcc	LOC108351553	mRNA stability	LOC108351553	0.03	940	0.02	2.5e-03	5.26	1.43e-07	0.47	FALSE
NAcc	Tuba1b	mRNA stability	Tuba1b	0.21	51	0.16	1.1e-17	-5.24	1.59e-07	0.5	FALSE
OFC	LOC100362820	gene expression	LOC100362820	0.18	15	0.06	1.2e-02	5.5	3.72e-08	0.32	FALSE
OFC	Spats2	gene expression	Spats2	0.28	1043	0.16	1.4e-04	-5.24	1.63e-07	0.46	FALSE
OFC	LOC102546778	mRNA stability	LOC102546778	0.16	1	0.12	1.1e-03	-5.22	1.77e-07	0.06	FALSE
PL	Faim2	alternative polyA	XM_017594665.2	0.06	1	0.09	1.3e-09	-5.22	1.79e-07	0.68	FALSE
PL	Kcnh3	alternative TSS	NM_017108.1	0.05	995	0.05	2.2e-06	-5.27	1.37e-07	0.52	FALSE
PL	Kcnh3	alternative TSS	NM_017108.1	0.03	995	0.03	2.9e-04	-5.28	1.28e-07	0.5	FALSE
PL	Kcnh3	alternative TSS	XM_039078511.1	0.03	995	0.02	1.8e-03	5.32	1.04e-07	0.44	FALSE
PL	Tmbim6	alternative TSS	XM_039078437.1	0.02	1027	0.02	5.4e-03	-5.24	1.62e-07	0.45	FALSE
PL	Faim2	gene expression	Faim2	0.06	988	0.08	4.9e-09	-5.36	8.54e-08	0.44	FALSE
PL	LOC102546778	gene expression	LOC102546778	0.08	1	0.11	8.6e-12	-5.22	1.82e-07	0.65	FALSE
PL	Mcrs1	gene expression	Mcrs1	0.05	971	0.05	4.8e-06	5.36	8.36e-08	0.53	FALSE
PL	Prkag1	gene expression	Prkag1	0.41	114	0.42	9.3e-50	5.18	2.20e-07	0.56	FALSE
PL	Tuba1b	gene expression	Tuba1b	0.47	393	0.28	2.2e-30	-5.2	1.97e-07	0.55	FALSE
PL	Wnt10b	gene expression	Wnt10b	0.03	58	0.03	4.6e-04	-5.19	2.07e-07	0.48	FALSE
PL	Faim2	isoform ratio	XM_017594665.2	0.04	988	0.03	1.5e-04	5.39	7.15e-08	0.54	FALSE
PL	Spats2	isoform ratio	NM_001395111.1	0.02	1043	0.01	1.7e-02	5.21	1.94e-07	0.36	FALSE
PL	Spats2	isoform ratio	XM_039078932.1	0.07	1043	0.04	1.3e-05	-5.32	1.02e-07	0.46	FALSE
PL	Tmbim6	intron excision ratio	chr7_130527706_130535190	0.02	1	0.02	6.3e-03	5.41	6.14e-08	0.13	FALSE
PL	Bcdin3d	mRNA stability	Bcdin3d	0.06	2	0.07	1.8e-08	-5.33	9.57e-08	0.56	FALSE
PL	Faim2	mRNA stability	Faim2	0.09	9	0.09	5.2e-10	-5.22	1.79e-07	0.59	FALSE
PL	LOC102546778	mRNA stability	LOC102546778	0.1	1032	0.09	1.6e-10	5.25	1.53e-07	0.56	FALSE
PL	Tuba1b	mRNA stability	Tuba1b	0.2	26	0.21	4.3e-23	-5.19	2.15e-07	0.48	TRUE
pVTA	Faim2	alternative polyA	NM_144756.2	0.1	988	0.03	1.5e-02	-5.39	7.10e-08	0.48	FALSE
pVTA	Faim2	alternative polyA	XM_017594665.2	0.19	988	0.12	1.0e-05	5.39	6.90e-08	0.56	FALSE
pVTA	Aqp5	gene expression	Aqp5	0.1	970	0.1	5.4e-05	-5.25	1.52e-07	0.38	FALSE
pVTA	Faim2	gene expression	Faim2	0.27	988	0.56	1.3e-28	-5.4	6.75e-08	0.59	FALSE
pVTA	LOC108351553	gene expression	LOC108351553	0.05	4	0.03	2.2e-02	-5.19	2.12e-07	0.35	FALSE
pVTA	Prph	gene expression	Prph	0.12	10	0.09	1.2e-04	5.22	1.81e-07	0.48	FALSE
pVTA	Spats2	gene expression	Spats2	0.18	1043	0.16	2.8e-07	-5.19	2.11e-07	0.48	FALSE
pVTA	Faim2	isoform ratio	XM_017594665.2	0.22	988	0.15	7.7e-07	5.39	6.99e-08	0.56	FALSE
pVTA	LOC102546778	mRNA stability	LOC102546778	0.09	1032	0.03	1.6e-02	5.21	1.88e-07	0.43	FALSE
RMTg	Faim2	gene expression	Faim2	0.29	988	0.18	1.6e-05	-5.33	9.58e-08	0.56	FALSE
RMTg	Spats2	gene expression	Spats2	0.16	1043	0.05	1.5e-02	-5.24	1.58e-07	0.35	FALSE
RMTg	Bcdin3d	mRNA stability	Bcdin3d	0.16	1037	0.06	1.2e-02	-5.3	1.16e-07	0.46	FALSE
RMTg	Dip2b	mRNA stability	Dip2b	0.13	1	0.11	7.4e-04	5.21	1.85e-07	0.07	FALSE
RMTg	Spats2	mRNA stability	Spats2	0.13	1043	0.09	2.5e-03	-5.24	1.61e-07	0.37	FALSE