Best TWAS P=2.134678e-07 · Best GWAS P=3.454874e-06 conditioned to 0.8163016
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Efhd1 | mRNA stability | ENSRNOG00000015596 | 0.50 | 0.18 | enet | 190 | 0.2 | 2.7e-22 | 4.4 | -5.1 | 3.6e-07 | -0.55 | 0.05 | 0.95 | FALSE |
| 2 | OFC | Efhd1 | mRNA stability | ENSRNOG00000015596 | 0.64 | 0.18 | blup | 1586 | 0.2 | 1.6e-05 | 4.6 | -5.2 | 2.1e-07 | -0.91 | 0.06 | 0.90 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.