Best TWAS P=5.80e-08 · Best GWAS P=3.37e-08 conditioned to 1e+00
Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
---|---|---|---|---|---|---|---|---|---|---|---|
Adipose | Spdef | gene expression | Spdef | 0.11 | 1 | 0.04 | 1.6e-05 | 5.42 | 5.8e-08 | 0.59 | TRUE |
LHb | Ilrun | gene expression | Ilrun | 0.81 | 1 | 0.27 | 3.3e-07 | 5.42 | 6.1e-08 | 0.74 | TRUE |
Liver | Snrpc | alternative TSS | XM_039098816.1 | 0.26 | 1 | 0.09 | 2.5e-10 | -5.42 | 5.8e-08 | 0.91 | FALSE |
Liver | Snrpc | isoform ratio | XM_039098816.1 | 0.31 | 1 | 0.12 | 6.8e-13 | -5.42 | 5.8e-08 | 0.91 | FALSE |