Hub : Traits : Liver weight, right :

chr20:5,086,090-7,380,732

Trait: Liver weight, right

Best TWAS P=5.799024e-08 · Best GWAS P=3.367881e-08 conditioned to 1

Associated models

# Tissue Gene Modality RNA phenotype h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 Adipose Spdef gene expression ENSRNOG00000000491 0.11 0.05 top1 1 0.05 7.4e-06 5.4 -5.4 5.8e-08 -0.61 0.07 0.77 TRUE
2 Liver Taf11 gene expression ENSRNOG00000024601 0.09 0.02 enet 58 0.03 5.0e-04 2.0 5.4 7.0e-08 0.38 0.62 0.29 TRUE
3 NAcc NA gene expression ENSRNOG00000058912 0.21 0.11 top1 1 0.11 2.2e-08 5.4 -5.4 7.0e-08 -0.60 0.08 0.91 TRUE
4 OFC Ilrun gene expression ENSRNOG00000038883 0.90 0.22 enet 209 0.52 1.5e-14 3.8 -5.2 1.9e-07 -0.98 0.11 0.89 TRUE
5 OFC Srpk1 intron excision ratio chr20:6668484:6669979 0.47 0.00 enet 171 0.07 8.9e-03 -2.6 5.1 2.9e-07 0.61 0.14 0.27 FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.