Hub : Traits : Liver weight, right :

chr1:258,394,596-260,518,987

Trait: Liver weight, right

Best TWAS P=1.491312e-08 · Best GWAS P=9.715627e-09 conditioned to 1

Associated models

# Tissue Gene Modality RNA phenotype h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 BLA Sfxn4 gene expression ENSRNOG00000036572 0.07 0.02 top1 1 0.02 2.1e-02 -5.2 5.2 2.5e-07 -0.83 0.06 0.05 FALSE
2 Brain Cacul1 isoform ratio ENSRNOT00000050617 0.14 0.11 top1 1 0.11 3.3e-10 -5.6 5.6 1.7e-08 -0.95 0.09 0.91 FALSE
3 Brain Cacul1 intron excision ratio chr1:259677583:259686255 0.12 0.08 enet 36 0.10 1.6e-09 -5.2 5.2 2.1e-07 -0.25 0.16 0.84 TRUE
4 Liver Cacul1 isoform ratio ENSRNOT00000050617 0.03 0.02 top1 1 0.02 1.3e-03 -5.1 5.1 2.8e-07 -0.94 0.07 0.04 TRUE
5 Liver Cacul1 mRNA stability ENSRNOG00000009954 0.03 0.01 top1 1 0.01 1.4e-02 -5.7 5.7 1.5e-08 -0.94 0.05 0.06 TRUE
6 NAcc Prlhr gene expression ENSRNOG00000009922 0.14 0.09 blup 1904 0.11 2.3e-08 -5.7 5.1 2.6e-07 -0.94 0.18 0.82 FALSE
7 NAcc Cacul1 isoform ratio ENSRNOT00000050617 0.05 0.05 blup 1781 0.05 9.6e-05 -5.2 5.4 8.6e-08 -0.94 0.32 0.63 FALSE
8 NAcc Cacul1 isoform ratio ENSRNOT00000084760 0.05 0.05 blup 1781 0.05 1.6e-04 -5.1 -5.3 8.8e-08 0.94 0.33 0.62 FALSE
9 OFC Rab11fip2 gene expression ENSRNOG00000009523 0.30 0.23 lasso 17 0.27 5.1e-07 -5.4 -5.4 8.7e-08 0.98 0.33 0.66 FALSE
10 OFC Rab11fip2 mRNA stability ENSRNOG00000009523 0.16 0.19 top1 1 0.19 2.9e-05 -5.4 -5.4 6.7e-08 0.89 0.12 0.07 FALSE
11 PL Rab11fip2 gene expression ENSRNOG00000009523 0.06 0.04 enet 76 0.05 1.5e-04 -5.2 -5.3 1.1e-07 0.91 0.36 0.64 FALSE
12 PL Cacul1 isoform ratio ENSRNOT00000050617 0.03 0.02 top1 1 0.02 1.8e-02 -5.1 5.1 3.1e-07 -0.90 0.06 0.04 FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.