Best TWAS P=1.49e-08 · Best GWAS P=9.72e-09 conditioned to 1e+00
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLA | Sfxn4 | gene expression | ENSRNOG00000036572 | 0.07 | 1 | 0.02 | 2.1e-02 | 5.16 | 2.47e-07 | 0.05 | FALSE |
| Brain | Cacul1 | isoform ratio | ENSRNOT00000050617 | 0.14 | 1 | 0.11 | 3.3e-10 | 5.64 | 1.66e-08 | 0.91 | FALSE |
| Brain | Cacul1 | intron excision ratio | chr1:259677583:259686255 | 0.12 | 36 | 0.1 | 1.6e-09 | 5.19 | 2.13e-07 | 0.84 | TRUE |
| Liver | Cacul1 | isoform ratio | ENSRNOT00000050617 | 0.03 | 1 | 0.02 | 1.3e-03 | 5.14 | 2.81e-07 | 0.04 | TRUE |
| Liver | Cacul1 | mRNA stability | ENSRNOG00000009954 | 0.03 | 1 | 0.01 | 1.4e-02 | 5.66 | 1.49e-08 | 0.06 | TRUE |
| NAcc | Prlhr | gene expression | ENSRNOG00000009922 | 0.14 | 1904 | 0.11 | 2.3e-08 | 5.15 | 2.65e-07 | 0.82 | FALSE |
| NAcc | Cacul1 | isoform ratio | ENSRNOT00000050617 | 0.05 | 1781 | 0.05 | 9.6e-05 | 5.35 | 8.65e-08 | 0.63 | FALSE |
| NAcc | Cacul1 | isoform ratio | ENSRNOT00000084760 | 0.05 | 1781 | 0.05 | 1.6e-04 | -5.35 | 8.84e-08 | 0.62 | FALSE |
| OFC | Rab11fip2 | gene expression | ENSRNOG00000009523 | 0.3 | 17 | 0.27 | 5.1e-07 | -5.35 | 8.73e-08 | 0.66 | FALSE |
| OFC | Rab11fip2 | mRNA stability | ENSRNOG00000009523 | 0.16 | 1 | 0.19 | 2.9e-05 | -5.4 | 6.65e-08 | 0.07 | FALSE |
| PL | Rab11fip2 | gene expression | ENSRNOG00000009523 | 0.06 | 76 | 0.05 | 1.5e-04 | -5.31 | 1.08e-07 | 0.64 | FALSE |
| PL | Cacul1 | isoform ratio | ENSRNOT00000050617 | 0.03 | 1 | 0.02 | 1.8e-02 | 5.12 | 3.11e-07 | 0.04 | FALSE |