Best TWAS P=3.491353e-07 · Best GWAS P=1.538177e-07 conditioned to 1
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | OFC | Anapc10 | gene expression | ENSRNOG00000018296 | 0.23 | 0.1 | lasso | 3 | 0.11 | 0.0014 | -5.1 | -5.1 | 3.5e-07 | 0.94 | 0.38 | 0.52 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.