Best TWAS P=9.676276e-08 · Best GWAS P=2.618798e-05 conditioned to 0.6059288
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Liver | NA | gene expression | ENSRNOG00000067835 | 0.47 | 0.03 | enet | 12 | 0.04 | 5e-05 | 4.1 | -5.3 | 9.7e-08 | -0.84 | 0.04 | 0.9 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.