chr20:1,304,706-4,179,420

Trait: Epididymis fat weight

Best TWAS P=1.98e-09 · Best GWAS P=1.27e-07 conditioned to 1.00e+00

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose Mdc1 alternative TSS XM_039098647.1 0.03 1269 0.01 2.4e-02 -5.36 8.49e-08 0.04 FALSE
Adipose Ppp1r10 gene expression Ppp1r10 0.02 1247 0.01 2.3e-02 -5.55 2.79e-08 0.07 FALSE
Adipose RT1-T24-1 gene expression RT1-T24-1 0.87 20 0.53 7.8e-69 -5.49 4.05e-08 0.05 FALSE
Adipose LOC108353253 isoform ratio XR_005497426.1 0.04 2434 0.01 2.2e-02 5.21 1.84e-07 0.36 FALSE
Adipose LOC108353253 isoform ratio XR_005497427.1 0.1 2434 0.07 1.3e-08 5.42 6.10e-08 0.18 FALSE
Adipose RT1-T24-1 isoform ratio NM_001410264.1 0.03 13 0 9.6e-02 5.62 1.87e-08 0.49 FALSE
Adipose RT1-CE13 intron excision ratio chr20_3317306_3317493 0.32 2566 0.05 6.9e-06 5.31 1.10e-07 0.56 FALSE
Adipose RT1-CE15 intron excision ratio chr20_3259966_3278514 0.26 2436 0.02 4.8e-03 5.42 6.02e-08 0.26 FALSE
Adipose RT1-CE15 intron excision ratio chr20_3317306_3317493 0.32 2436 0.05 7.0e-06 5.47 4.49e-08 0.62 FALSE
Adipose RT1-CE16 intron excision ratio chr20_3259966_3278514 0.27 2434 0.02 5.0e-03 5.45 4.93e-08 0.26 FALSE
Adipose RT1-CE16 intron excision ratio chr20_3317306_3317493 0.33 2434 0.05 7.1e-06 5.49 3.98e-08 0.62 FALSE
Adipose RT1-S3 intron excision ratio chr20_2597970_2672329 0.39 7 0.14 3.7e-15 5.83 5.51e-09 0.62 FALSE
Adipose RT1-S3 intron excision ratio chr20_2671794_2672329 0.36 5 0.17 5.4e-18 -5.62 1.91e-08 0.65 FALSE
Adipose RT1-T24-1 intron excision ratio chr20_2690616_2690922 0.23 1208 0.03 1.8e-04 -5.83 5.55e-09 0.65 FALSE
Adipose RT1-T24-1 intron excision ratio chr20_2723920_2724226 0.2 1208 0.02 2.7e-03 5.91 3.51e-09 0.28 FALSE
Adipose RT1-T24-1 intron excision ratio chr20_2741359_2741537 0.18 1208 0.01 1.2e-02 -5.72 1.04e-08 0.1 FALSE
Adipose RT1-T24-1 intron excision ratio chr20_2741359_2774720 0.32 1208 0.04 1.9e-05 -5.87 4.25e-09 0.5 FALSE
Adipose RT1-T24-1 intron excision ratio chr20_2773698_2774009 0.23 1208 0.03 1.2e-04 -5.82 6.04e-09 0.67 FALSE
Adipose RT1-T24-3 intron excision ratio chr20_2690616_2690922 0.23 1161 0.03 1.9e-04 -5.87 4.34e-09 0.66 FALSE
Adipose RT1-T24-3 intron excision ratio chr20_2694069_2724607 0.38 23 0.04 1.3e-05 -5.41 6.20e-08 0.06 FALSE
Adipose RT1-T24-3 intron excision ratio chr20_2694312_2694499 0.11 1161 -0 3.4e-01 5.68 1.32e-08 0.09 FALSE
Adipose RT1-T24-3 intron excision ratio chr20_2694312_2725194 0.22 10 0.03 6.9e-04 -5.69 1.30e-08 0.18 TRUE
Adipose RT1-T24-3 intron excision ratio chr20_2723920_2724226 0.19 1161 0.02 2.7e-03 5.95 2.66e-09 0.28 FALSE
Adipose RT1-T24-3 intron excision ratio chr20_2724501_2724607 0.39 17 0.07 3.1e-08 5.32 1.04e-07 0.06 FALSE
Adipose RT1-T24-3 intron excision ratio chr20_2773698_2774009 0.23 1161 0.03 1.2e-04 -5.86 4.73e-09 0.68 FALSE
Adipose RT1-T24-4 intron excision ratio chr20_2690616_2690922 0.23 1129 0.03 1.9e-04 -5.87 4.43e-09 0.67 FALSE
Adipose RT1-T24-4 intron excision ratio chr20_2691672_2692062 0.28 1129 0.06 2.7e-07 5.89 3.87e-09 0.69 FALSE
Adipose RT1-T24-4 intron excision ratio chr20_2694069_2724607 0.38 23 0.04 1.3e-05 -5.41 6.18e-08 0.06 FALSE
Adipose RT1-T24-4 intron excision ratio chr20_2723920_2724226 0.19 1129 0.02 2.7e-03 5.95 2.69e-09 0.28 FALSE
Adipose RT1-T24-4 intron excision ratio chr20_2724501_2724607 0.39 17 0.07 3.1e-08 5.32 1.03e-07 0.07 FALSE
Adipose RT1-T24-4 intron excision ratio chr20_2741359_2741537 0.19 1129 0.01 1.2e-02 -5.76 8.55e-09 0.1 FALSE
Adipose RT1-T24-4 intron excision ratio chr20_2773698_2774009 0.23 1129 0.03 1.2e-04 -5.85 4.83e-09 0.69 FALSE
Adipose RT1-T24-1 mRNA stability RT1-T24-1 0.86 12 0.31 2.0e-35 5.73 1.00e-08 0.05 FALSE
Adipose Tubb5 mRNA stability Tubb5 0.12 1269 0.09 2.0e-10 5.23 1.72e-07 0.67 FALSE
BLA RT1-N3 alternative TSS NM_001008855.2 0.29 3 0.09 2.4e-05 -5.21 1.85e-07 0.75 TRUE
BLA LOC120098967 gene expression LOC120098967 0.6 1258 0.36 6.8e-20 -5.66 1.54e-08 0.71 FALSE
BLA Prr3 gene expression Prr3 0.19 7 0.06 2.9e-04 5.55 2.91e-08 0.18 FALSE
BLA RT1-N3 gene expression RT1-N3 0.69 26 0.38 3.0e-21 -5.92 3.13e-09 0.76 FALSE
BLA RT1-CE10 intron excision ratio chr20_3276101_3276342 0.13 15 0.01 1.4e-01 -5.2 2.03e-07 0.35 FALSE
BLA RT1-CE11 intron excision ratio chr20_3258719_3259691 0.8 2814 0.29 8.5e-16 -5.21 1.94e-07 0.03 FALSE
BLA RT1-CE11 intron excision ratio chr20_3276101_3276342 0.13 8 0.01 1.4e-01 -5.2 2.03e-07 0.33 FALSE
BLA RT1-CE12 intron excision ratio chr20_3258719_3259691 0.8 2774 0.29 9.2e-16 -5.22 1.76e-07 0.02 FALSE
BLA RT1-CE13 intron excision ratio chr20_3258719_3259691 0.82 2580 0.29 1.3e-15 -5.29 1.19e-07 0.03 FALSE
BLA RT1-CE14 intron excision ratio chr20_3258719_3259691 0.82 35 0.29 7.9e-16 -5.34 9.15e-08 0.03 TRUE
BLA RT1-CE14 intron excision ratio chr20_3276101_3276342 0.12 11 0.02 3.1e-02 -5.18 2.21e-07 0.33 FALSE
BLA RT1-CE15 intron excision ratio chr20_3258719_3259691 0.83 26 0.29 8.0e-16 -5.34 9.27e-08 0.03 FALSE
BLA RT1-CE15 intron excision ratio chr20_3259966_3317493 0.58 2450 0.21 1.4e-11 5.29 1.24e-07 0.01 FALSE
BLA RT1-CE15 intron excision ratio chr20_3276101_3276342 0.12 1 0 2.6e-01 5.21 1.84e-07 0.04 TRUE
BLA RT1-CE16 intron excision ratio chr20_3258719_3259691 0.83 28 0.29 7.9e-16 -5.34 9.40e-08 0.02 FALSE
BLA RT1-CE16 intron excision ratio chr20_3259966_3317493 0.58 2448 0.21 1.4e-11 5.3 1.19e-07 0.01 FALSE
BLA RT1-CE16 intron excision ratio chr20_3276101_3276342 0.13 9 0.02 4.4e-02 -5.21 1.84e-07 0.33 FALSE
Brain Flot1 gene expression Flot1 0.32 1315 0.2 1.2e-18 5.94 2.88e-09 0.01 FALSE
Brain Gnl1 gene expression Gnl1 0.25 1262 0.19 5.6e-17 5.47 4.49e-08 0.71 FALSE
Brain LOC108349027 gene expression LOC108349027 0.2 1222 0.14 4.3e-13 5.54 3.07e-08 0.71 FALSE
Brain RT1-N3 gene expression RT1-N3 0.45 1052 0.32 2.1e-30 -5.54 2.98e-08 0.78 FALSE
Brain RT1-N3 isoform ratio NM_001008855.2 0.21 8 0.15 2.1e-13 5.81 6.11e-09 0.73 TRUE
Brain RT1-N3 isoform ratio XM_006255908.4 0.33 3 0.26 6.3e-24 -5.21 1.94e-07 0.78 FALSE
Brain RT1-T24-4 isoform ratio XM_039099254.1 0.21 14 0.2 3.5e-18 5.33 9.77e-08 0.01 FALSE
Brain Atat1 intron excision ratio chr20_2851533_2854003 0.05 1296 0.02 1.1e-02 -5.86 4.58e-09 0.24 FALSE
Brain Ddr1 intron excision ratio chr20_3058925_3060490 0.07 1315 0.02 8.7e-03 5.56 2.67e-08 0.07 FALSE
Brain RT1-CE11 intron excision ratio chr20_3258719_3259691 0.77 9 0.34 9.1e-33 -5.3 1.17e-07 0.07 FALSE
Brain RT1-CE12 intron excision ratio chr20_3258719_3259691 0.76 9 0.34 8.4e-33 -5.29 1.19e-07 0.07 FALSE
Brain RT1-CE13 intron excision ratio chr20_3258719_3259691 0.71 9 0.34 6.7e-33 -5.29 1.24e-07 0.08 FALSE
Brain RT1-CE15 intron excision ratio chr20_3258719_3259691 0.69 9 0.34 6.1e-33 -5.28 1.29e-07 0.08 FALSE
Brain RT1-CE16 intron excision ratio chr20_3258719_3259691 0.67 9 0.34 5.9e-33 -5.28 1.32e-07 0.08 FALSE
Brain RT1-S3 intron excision ratio chr20_2597970_2672329 0.06 1120 0.03 1.4e-03 5.67 1.42e-08 0.69 FALSE
Brain RT1-S3 intron excision ratio chr20_2671794_2672329 0.04 8 0.01 3.1e-02 5.96 2.48e-09 0.46 FALSE
Brain RT1-T24-3 intron excision ratio chr20_2694069_2745591 0.19 1206 0.06 1.5e-06 5.22 1.80e-07 0.01 FALSE
Brain RT1-T24-3 intron excision ratio chr20_2694312_2725194 0.06 1206 0.02 9.8e-03 5.77 7.91e-09 0.11 FALSE
Brain RT1-T24-3 intron excision ratio chr20_2724501_2724607 0.4 2 0.17 6.6e-16 -5.58 2.36e-08 0.01 TRUE
Brain RT1-T24-4 intron excision ratio chr20_2691672_2692062 0.31 7 0.13 6.6e-12 5.71 1.12e-08 0.01 FALSE
Brain RT1-T24-4 intron excision ratio chr20_2694069_2745591 0.19 1174 0.06 1.5e-06 5.22 1.75e-07 0.01 FALSE
Brain RT1-T24-4 intron excision ratio chr20_2724501_2724607 0.4 2 0.17 6.4e-16 -5.58 2.37e-08 0.01 FALSE
Brain RT1-S3 mRNA stability RT1-S3 0.24 1120 0.23 5.1e-21 -5.47 4.39e-08 0.01 FALSE
Eye Tcf19 mRNA stability Tcf19 0.39 2253 0.06 4.4e-02 5.18 2.18e-07 0.09 FALSE
IL RT1-T24-3 alternative polyA XM_039098963.1 0.32 1206 0.16 1.3e-04 -5.45 5.07e-08 0.03 FALSE
IL LOC120098967 gene expression LOC120098967 0.49 1258 0.18 4.2e-05 -5.51 3.61e-08 0.63 FALSE
IL RT1-T24-3 intron excision ratio chr20_2694069_2745591 0.25 1206 0.04 3.2e-02 5.53 3.14e-08 0.09 FALSE
IL RT1-T24-4 intron excision ratio chr20_2694069_2745591 0.25 1174 0.04 3.3e-02 5.54 3.02e-08 0.09 FALSE
LHb RT1-T24-3 alternative polyA NM_001166403.1 0.39 20 0.21 1.2e-05 5.26 1.41e-07 0.02 FALSE
LHb RT1-T24-3 alternative polyA XM_039098963.1 0.39 6 0.2 1.3e-05 -5.25 1.51e-07 0.02 TRUE
LHb Flot1 gene expression Flot1 0.17 1315 0.1 2.8e-03 5.5 3.71e-08 0.07 FALSE
LHb LOC120098967 gene expression LOC120098967 0.46 22 0.15 2.0e-04 5.76 8.43e-09 0.58 FALSE
Liver RT1-T24-3 alternative polyA NM_001166403.1 0.27 12 0.1 1.5e-11 -5.49 4.13e-08 0.01 FALSE
Liver RT1-T24-3 alternative polyA XM_039098963.1 0.32 41 0.14 2.2e-15 5.51 3.54e-08 0.01 FALSE
Liver RT1-N3 alternative TSS XM_039098421.1 0.2 1006 0.16 6.7e-17 5.43 5.77e-08 0.02 FALSE
Liver Gnl1 gene expression Gnl1 0.12 1217 0.08 5.2e-09 -5.87 4.37e-09 0.01 FALSE
Liver LOC108349027 gene expression LOC108349027 0.07 1177 0.03 3.4e-04 5.69 1.30e-08 0.7 FALSE
Liver LOC120098967 gene expression LOC120098967 0.28 1213 0.17 7.8e-19 -5.58 2.36e-08 0.68 FALSE
Liver RT1-S3 gene expression RT1-S3 0.12 1075 0.07 3.2e-08 -5.93 3.10e-09 0.13 FALSE
Liver RT1-T24-4 gene expression RT1-T24-4 0.13 1129 0.08 7.4e-09 5.68 1.38e-08 0.72 FALSE
Liver RT1-CE11 intron excision ratio chr20_3276691_3298501 0.39 31 0.14 1.2e-15 -5.48 4.27e-08 0.62 FALSE
Liver RT1-CE13 intron excision ratio chr20_3317306_3317493 0.47 2566 0.11 3.3e-12 5.37 7.89e-08 0.61 FALSE
Liver RT1-CE14 intron excision ratio chr20_3276691_3298501 0.43 22 0.15 2.8e-16 -5.44 5.29e-08 0.66 FALSE
Liver RT1-CE14 intron excision ratio chr20_3317306_3317493 0.47 2476 0.11 3.0e-12 5.46 4.83e-08 0.65 FALSE
Liver RT1-CE15 intron excision ratio chr20_3276691_3298501 0.44 19 0.15 2.9e-16 -5.41 6.18e-08 0.67 FALSE
Liver RT1-CE15 intron excision ratio chr20_3317306_3317493 0.48 2436 0.11 2.8e-12 5.53 3.21e-08 0.67 FALSE
Liver RT1-CE16 intron excision ratio chr20_3317306_3317493 0.48 2434 0.11 2.7e-12 5.54 2.96e-08 0.67 FALSE
Liver RT1-S3 intron excision ratio chr20_2597970_2672329 0.48 6 0.17 7.7e-19 5.79 6.97e-09 0.71 FALSE
Liver RT1-S3 intron excision ratio chr20_2671794_2672329 0.43 10 0.17 3.9e-18 -5.79 6.90e-09 0.71 FALSE
Liver RT1-T24-3 intron excision ratio chr20_2694312_2725194 0.37 1161 0.07 1.5e-08 5.94 2.82e-09 0.03 FALSE
Liver RT1-T24-4 intron excision ratio chr20_2691465_2691643 0.23 1129 0.02 1.2e-03 5.92 3.26e-09 0.14 FALSE
Liver RT1-T24-4 intron excision ratio chr20_2691928_2692062 0.18 4 0.03 1.6e-04 -5.39 6.91e-08 0.35 FALSE
Liver RT1-T24-4 intron excision ratio chr20_2741359_2741537 0.1 1129 0.02 2.0e-03 -5.73 9.84e-09 0.66 FALSE
NAcc RT1-S3 alternative TSS NM_001008886.2 0.03 1120 0.02 2.5e-03 -5.87 4.39e-09 0.14 FALSE
NAcc RT1-S3 alternative TSS XM_006255917.4 0.03 1120 0.03 5.6e-04 5.82 6.05e-09 0.07 FALSE
NAcc LOC108349027 gene expression LOC108349027 0.21 4 0.2 9.4e-23 5.94 2.89e-09 0.72 FALSE
NAcc LOC120098827 gene expression LOC120098827 0.25 22 0.23 8.2e-27 -5.27 1.39e-07 0.74 FALSE
NAcc LOC120098967 gene expression LOC120098967 0.4 100 0.39 3.9e-48 5.83 5.46e-09 0.72 FALSE
NAcc RT1-N3 gene expression RT1-N3 0.7 37 0.33 2.3e-39 -5.9 3.59e-09 0.77 FALSE
OFC Prr3 gene expression Prr3 0.26 1262 0.11 1.7e-03 -5.83 5.59e-09 0.28 FALSE
OFC RT1-CE16 gene expression RT1-CE16 0.92 2448 0.51 3.6e-14 -5.21 1.89e-07 0.01 FALSE
OFC RT1-N3 gene expression RT1-N3 0.64 462 0.4 1.1e-10 6 2.00e-09 0.74 FALSE
OFC RT1-T24-3 gene expression RT1-T24-3 0.72 13 0.38 6.3e-10 5.89 3.93e-09 0.01 FALSE
OFC RT1-CE14 isoform ratio NR_172019.1 0.15 2490 0.06 1.7e-02 5.46 4.83e-08 0.18 FALSE
OFC RT1-CE11 intron excision ratio chr20_3258719_3259691 0.63 2814 0.19 3.3e-05 -5.32 1.03e-07 0.06 FALSE
OFC RT1-CE12 intron excision ratio chr20_3258719_3259691 0.63 2774 0.2 2.2e-05 -5.33 9.98e-08 0.06 FALSE
OFC RT1-CE13 intron excision ratio chr20_3258719_3259691 0.61 2580 0.21 1.2e-05 -5.33 9.66e-08 0.07 FALSE
OFC RT1-CE15 intron excision ratio chr20_3258719_3259691 0.61 2450 0.21 9.9e-06 -5.42 5.99e-08 0.07 FALSE
OFC RT1-CE16 intron excision ratio chr20_3258719_3259691 0.61 2448 0.21 9.4e-06 -5.43 5.78e-08 0.07 FALSE
OFC RT1-T24-1 intron excision ratio chr20_2723920_2724226 0.28 11 0.08 6.3e-03 -5.96 2.59e-09 0.28 FALSE
OFC RT1-T24-3 intron excision ratio chr20_2723920_2724226 0.25 1206 0.04 4.2e-02 5.96 2.56e-09 0.28 FALSE
OFC RT1-T24-4 intron excision ratio chr20_2723920_2724226 0.25 1174 0.04 4.2e-02 5.96 2.57e-09 0.28 FALSE
PL Ddr1 alternative TSS XM_017601560.2 0.04 1315 0.03 1.5e-04 -5.26 1.45e-07 0.02 FALSE
PL LOC120098829 alternative TSS XR_005497433.1 0.07 2580 0.05 7.1e-06 5.38 7.32e-08 0.72 FALSE
PL LOC120098829 alternative TSS XR_005497434.1 0.05 2580 0.02 1.9e-03 -5.49 3.91e-08 0.69 FALSE
PL LOC120098829 alternative TSS XR_005497433.1 0.06 2580 0.03 8.2e-04 5.38 7.55e-08 0.65 FALSE
PL LOC120098829 alternative TSS XR_005497434.1 0.06 2580 0.03 3.5e-04 -5.51 3.59e-08 0.67 FALSE
PL LOC120098967 gene expression LOC120098967 0.74 79 0.43 3.5e-52 6 1.98e-09 0.72 TRUE
PL RT1-N3 gene expression RT1-N3 0.5 66 0.45 7.7e-55 -5.96 2.59e-09 0.77 FALSE
PL Mdc1 mRNA stability Mdc1 0.11 1315 0.09 5.5e-10 -5.82 5.71e-09 0.01 FALSE
pVTA RT1-CE5 alternative polyA XM_039098663.1 0.29 39 0.13 3.2e-06 -5.56 2.63e-08 0.57 FALSE
pVTA LOC120098850 alternative TSS XR_005497495.1 0.13 74 0.1 6.3e-05 5.19 2.15e-07 0.53 FALSE
pVTA LOC120098850 alternative TSS XR_005497496.1 0.1 1376 0.06 1.5e-03 5.41 6.47e-08 0.42 FALSE
pVTA LOC120098967 gene expression LOC120098967 0.45 33 0.33 8.1e-15 5.82 5.80e-09 0.69 FALSE
pVTA Prr3 gene expression Prr3 0.22 42 0.06 2.1e-03 5.34 9.24e-08 0.35 FALSE
pVTA RT1-N3 gene expression RT1-N3 0.38 1 0.24 1.3e-10 5.19 2.07e-07 0.8 FALSE
pVTA RT1-N3 isoform ratio XM_006255908.4 0.37 216 0.13 2.4e-06 5.2 1.96e-07 0.75 FALSE
pVTA RT1-CE14 intron excision ratio chr20_3297603_3297737 0.25 39 0.23 3.8e-10 -5.5 3.86e-08 0.04 FALSE
pVTA RT1-CE15 intron excision ratio chr20_3297603_3297737 0.24 35 0.23 3.8e-10 -5.5 3.80e-08 0.04 FALSE
pVTA RT1-CE16 intron excision ratio chr20_3257619_3257752 0.17 2448 0.09 7.1e-05 -5.25 1.50e-07 0.04 FALSE
pVTA RT1-S3 mRNA stability RT1-S3 0.21 7 0.1 6.8e-05 -5.67 1.40e-08 0.23 FALSE
RMTg LOC120098967 gene expression LOC120098967 0.18 1 0.09 1.9e-03 5.19 2.07e-07 0.06 FALSE
RMTg Ppp1r18 gene expression Ppp1r18 0.26 1315 0.07 6.0e-03 5.68 1.37e-08 0.46 FALSE
RMTg RT1-CE14 isoform ratio NR_172019.1 0.14 2490 0.06 9.4e-03 -5.23 1.73e-07 0.07 FALSE
RMTg RT1-CE14 isoform ratio XR_008934201.1 0.15 2490 0.07 5.8e-03 5.24 1.63e-07 0.07 FALSE
RMTg RT1-CE15 intron excision ratio chr20_3297603_3297737 0.26 2450 0.16 5.4e-05 5.2 2.00e-07 0.08 FALSE
RMTg RT1-CE16 intron excision ratio chr20_3297603_3297737 0.27 2448 0.16 5.3e-05 5.2 1.96e-07 0.08 FALSE